A second pathway for regeneration of adult exocrine and endocrine pancreas: A possible recapitulation of embryonic development

Diabetes

Volumn 42, Issue 12, 1993, Pages 1715-1720

  Bonner Weir, Susan ^a,b   Baxter, Leslie A ^a   Schuppin, George T ^a   Smith, Fannie E ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b JOSLIN DIABETES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; GLUCAGON; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EPITHELIUM CELL; MALE; NONHUMAN; PANCREAS; PANCREAS ISLET; PANCREAS RESECTION; PRIORITY JOURNAL; RAT; REGENERATION; STEM CELL;

ANIMAL; CELL DIFFERENTIATION; CELL DIVISION; DNA; EMBRYO AND FETAL DEVELOPMENT; EPITHELIAL CELLS; EPITHELIUM; ISLETS OF LANGERHANS; MALE; PANCREAS; PANCREATECTOMY; PANCREATIC DUCTS; RATS; RATS, SPRAGUE-DAWLEY; REGENERATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0027449197     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.42.12.1715     Document Type: Article

References (28)

1. Pictet RL, Clark WR, Williams RH, Rutter, WJ: An ultrastructural analysis of the developing embryonic pancreas. Develop Biol 29: 436-67, 1972
2. Pictet RL, Rutter WJ: Development of the embryonic endocrine pancreas. In Handbook of Physiology: The Endocrine Pancreas. Section 8, Vol. 1. Steiner D, Freinkel N, Eds. Baltimore, MD, Williams and Wilkins, 1972, p. 25-66
3. Hellerstrom C, Swenne I, Andersson A: Islet cell replication and diabetes. In The Pathology of the Endocrine Pancreas. Lefebvre PJ, Pipeleers DG, Eds. Heidelberg, Germany, Springer-Verlag, 1988, p. 141-70
4. Elsasser HP, Lutcke H, Kern HF: Acinar and duct cell replication and regeneration. In The Exocrine Pancreas: Biology, Pathobiology and Diseases. Go VLW, Dimagno EP, Gardner JD, Lebenthal E, Ceber HA, Scheele GA, Eds. New York, Raven, 1986, p. 45-53
5. Bonner-Weir S, Trent DF, Weir GC: Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 71:1544-53, 1983
6. Brockenbrough JS, Weir GC, Bonner-Weir S: Discordance of exocrine and endocrine growth following 90% partial pancreatectomy in the rat. Diabetes 37:232-36, 1988
7. Smith FE, Rosen KM, Villa-Komaroff L, Weir GC, Bonner-Weir S: Enhanced insulin-like growth factor I gene expression in the regenerating rat pancreas. Proc Natl Acad Sci USA 8:6152-56, 1991
8. DeFazio A, Leary JA, Medley DW, Tattersall MHN: Immunohistochemical detection of proliferating cells in vivo. J Histo Cytochem 35:571-77, 1987
9. Githens S, Holmquist DRG, Whelan JF, Ruby, JR: Characterization of ducts isolated from the pancreas of the rat. J Cell Biol 85:122-35, 1980
10. Weaver CV, Sorenson RL, Kaung HC: Immunocytochemical localization of insulin-immunoreactive cells in the ducts of rats treated with trypsin inhibitor. Diabetologia 28:781-85, 1985
11. Gu D, Sarvetnick N: Epithelial cell proliferation and islet neogenesis in IFN-γ transgenic mice. Development 118:33-46, 1993
12. Wang TC, Bonner-Weir S, Oates P, Chulak MB, Simon B, Merlino GT, Schmidt EV, Brand SJ: Pancreatic gastrin stimulates differentiation of TGF-α induced ductular precursor cells. J Clin Invest 92:1349-56, 1993
13. Rosenberg L, Vinik AI: Trophic stimulation of the ductular islet cell axis: a new approach to the treatment of diabetes. Adv Exp Med Biol 321:95-104, 1992
14. Gepts W: Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 14:619-33, 1965
15. Bockman DE, Black O Jr, Mills JR, Webster PD: Origin of tubular complexes developing during induction of pancreatic adenocarcinoma by 7,12-dimethylbenz(a)anthracene. Am J Pathol 90:645-51, 1978
16. Bockman DE, Boydston WR, Anderson WC: Origin of tubular complexes in human chronic pancreatitis. Am J Surg 144:243-49, 1982
17. Cubilla AL, Fitzgerald PJ: Morphological patterns of primary nonendocrine human pancreas carcinoma. Cancer Res 35:2234-48, 1975
18. Parsa I, Longnecker DS, Scarpelli DG, Pour P, Reddy JK, Lefkowitz M: Ductal metaplasia of human exocrine pancreas and its association with carcinoma. Cancer Res 45:1285-90, 1985
19. Porta EA, Stein AA, Patterson P: Ultrastructural changes of the pancreas and liver in cystic fibrosis. Am J Clin Pathol 42:451-65, 1964
20. Elsasser HP, Adler G, Kern HF: Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat Pancreas 1:421-29, 1986
21. Willemer S, Elsasser HP, Kern HF, Adler G: Tubular complexes in cerulein- and oleic acid-induced pancreatitis in rats: glycoconjugate pattern, immunocytochemical, and ultrastructural findings. Pancreas 2:669-75, 1987
22. DeLisle RC, Grendell JH, Williams JA: Growing pancreatic acinar cells (postpancreatitis and fetal) express a ductal antigen. Pancreas 5:381-88, 1990
23. Dreiling DA, Bordalo OR, Noronha M, Greenstein R: Update: big duct, little duct or toxic metabolic pathogenesis of pancreatitis. Am J Gastroenterol 71:424-26, 1979
24. Dudek RW, Lawrence IE Jr, Hill RS, Johnson RC: Induction of islet cytodifferentiation by fetal mesenchyme in adult pancreatic ductal epithelium. Diabetes 40:1041-48, 1991
25. Rao MS, Yeldandi AV, Reddy JK: Stem cell potential of ductular and periductular cells in the adult rat pancreas. Cell Diff Dev 29:155-63, 1990
26. Nelson C, Shen L-P, Meister A, Fodor E, Rutter WJ: Pan; a transcriptional regulator that binds chymotrypsin, insulin and AP-4 enhancer motifs. Genes Dev 4:1035-43, 1990
27. Knepel W, Vallejo M, Chafitz JA, Habener JF: The pancreatic islet-specific glucagon G3 transcription factors recognize control elements in the rat somatostatin and insulin-I genes. Mol Endocrinol 5:1457-66, 1991
28. Wheeler MB, Nishitani J, Buchan AMJ, Kopin AS, Chey WY, Cnang T-M, Leiter AB: Identification of a transcriptional enhancer important for enteroendocrine and pancreatic islet cell-specific expression of the secretin gene. Mol Cell Biol 12:3531-39, 1992