Effect of captopril on vasoconstriction and Ca2+ fluxes in aortic smooth muscle

Hypertension

Volumn 22, Issue 6, 1993, Pages 806-811

  Zhu, Zhiming ^a   Tepel, Martin ^a   Neusser, Marcus ^a   Mehring, Norbert ^a   Zidek, Walter ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Angiotensin converting enzyme inhibitors; Calcium channel; Captopril; Muscle, smooth, vascular

Indexed keywords

ALPHA ACTIN; ANGIOTENSIN; BRADYKININ; CALCIUM CHANNEL; CALCIUM ION; CAPTOPRIL; ENALAPRILAT; FURA 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; SPONTANEOUSLY HYPERTENSIVE RAT;

ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANIMAL; AORTA, THORACIC; BRADYKININ; CALCIUM; CALCIUM CHANNELS; CAPTOPRIL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EGTAZIC ACID; ENALAPRILAT; HYPERTENSION; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TIME FACTORS; TISSUE CULTURE; VASOCONSTRICTION;

EID: 0027440151     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.22.6.806     Document Type: Article

References (23)

1. Ondetti MA, Rubin B, Cushman DW. Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science. 1977;196:441-444.
2. Velletri P, Bean BL. The effects of captopril on rat aortic angiotensin-converting enzyme. J Cardiovasc Pharmacol. 1982;4: 315-325.
3. Unger T, Ganten D, Lange RE, Schölkens BA. Persistent tissue converting enzyme inhibition following chronic treatment with Hoe498 and MK421 in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1985;7:36-41.
4. Cohen ML, Kurz KD. Angiotensin converting enzyme inhibition in tissues from spontaneously hypertensive rats after treatment With captopril or MK-421. J Pharmacol Exp Ther. 1982;220:63-69.
5. Gavras I. Bradykinin-mediated effects of ACE inhibition. Kidney Int. 1992;42:1020-1029.
6. Kikta DC, Fregly MJ. Effect of in vitro administration of captopril on vascular reactivity of rat aorta. Hypertension. 1982;4:118-124.
7. Antonaccio MJ, Kerwin L. Pre- and postjunctional inhibition of vascular sympathetic function by captopril in SHR: implication of vascular angiotensin II in hypertension and antihypertensive actions of captopril. Hypertension. 1981;3(suppl I):I-54-I-62.
8. +-ATPase. Clin Physiol Biochem. 1989;7:101-108.
9. Sada T, Koike H, Ikeda M, Sato K, Ozaki H, Karaki H. Cytosolic free calcium in hypertensive rats. Hypertension. 1990;16:245-251.
10. Zidek W, Ottens E, Heckmann U. Transmission of hypertension in rats by cross-circulation. Hypertension. 1989;14:61-65.
11. Ross R. The smooth muscle cell, II: growth of smooth muscle in culture and formation of elastic fibers. Cell biol. 1971;50:172-186.
12. Franks DJ, Plamondon J, Hamet P. An increase in adenylate cyclase activity precedes DNA synthesis in cultured vascular smooth muscle cells. J Cell Physiol. 1984;119:41-45.
13. Bendhack LM, Sharma RV, Bhalla RC. Altered signal transduction in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension. 1992;19(suppl II):II-42-II-48.
14. 2+ metabolism of isolated resistance arteries and cultured vascular myocytes of spontaneously hypertensive and Wistar-Kyoto normotensive rats. J Hypertens. 1990;8: 35-43.
15. 2+ indicators with greatly improved fluorescence properties. J Biol Chem. 1985;260:3440-3450.
16. Williams DA, Fogarty KE, Tsien RY, Fay FS. Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using fura-2. Nature. 1985;318:558-561.
17. Capponi AM, Lew PD, Vallotton MB. Cytosolic free calcium levels in monolayers of cultured rat aortic smooth muscle cells: effects of angiotensin II and vasopressin. J Biol Chem. 1985;260:7836-7842.
18. +-adenosine triphosphatase on vascular action of vasopressin. J Clin Invest. 1990;86:1241-1248.
19. Cobbold PH, Rink TJ. Fluorescence and bioluminescence measurement of cytoplasmic free calcium. Biochem J. 1987;248: 313-328.
20. Simonson MS, Dunn MJ. Ca2+ signaling by distinct endothelin peptides in glomerular mesangial cells. Exp Cell Res. 1991;192: 148-156.
21. i. Am J Physiol. 1992;263:C635-C641.
22. Schiffers PM, Struyker-Boudier HA, De Mey JG. Effects of angiotensin II and angiotensin converting enzyme inhibitors on contractile and growth responses in isolated carotid arteries of the rat. Basic Res Cardiol. 1991;86(suppl 1):83-89.
23. Duchin KL, Singhvi SM, Willard DA. Captopril kinetics. Clin Pharmacol Ther. 1982;31:452-459.