Recombination activating genes-1 and -2 of the rabbit: Cloning and characterization of germline and expressed genes

Molecular Immunology

Volumn 30, Issue 11, 1993, Pages 1021-1032

  Fuschiotti, Patrizia ^a   Harindranath, Nagaradona ^b   Mage, Rose G ^a   McCormack, Wayne T ^c   Dhanarajan, Pushparani ^d   Roux, Kenneth H ^d  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d FLORIDA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; DNA SEQUENCE; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BLOTTING, NORTHERN; CLONING, MOLECULAR; DNA; GENES, RAG-1; MOLECULAR SEQUENCE DATA; PROTEINS; RABBITS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; GALLUS GALLUS; ORYCTOLAGUS CUNICULUS;

EID: 0027432463     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(93)90127-W     Document Type: Article

References (38)

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2. Ha allotype gene that is deleted in Alicia mutants; somatic hypermutation/conversion may play a major role in generating the heterogeneity of rabbit heavy chain variable region sequence
3. Regulation of genome rearrangement events during lymphocyte differentiation
4. Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits
5. Sequencing with Taq DNA polymerase
6. Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion
7. H chromosomal region
8. The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
9. A technique; for radiolabeling DNA restriction fragments to high specific activity
10. H pseudogenes that could serve as donor sequences for latent allotype expression
11. More is better: activators and repressors from the same gene
12. H genes
13. Identification of a DNA binding protein that recognizes the nonamer recombinational signal sequences of immunoglobulin genes
14. V(D)J recombination: a functional definition of the joining signals
15. Endonucleolitic activity that cleaves immunoglobulin recombination sequences
16. Diversity of the immunoglobulin gene superfamily
17. Sequence and chromosome assignment to 11p13-p12 of human RAG genes
18. Sequences of Proteins of Immunological Interest
19. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
20. In-situ hybridization to agarose gels
21. Developmental stage specificity of the V(D)J recombination activity
22. H gene structure and diversity in Heterodontus, a phylogenetically primitive shark
23. Ha allotypes of the rabbit
24. Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion
25. RAG-1 deficient mice have no mature B and T lymphocytes
26. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
27. The recombination activating genes RAG-1 and RAG-2 are on chromosome 11p in humans and chromosome 2p in mice
28. 2 rabbit. Evidence for gene conversion at both the germline and somatic levels
29. DNA sequencing with chain terminating inhibitors
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31. The V(D)J recombination activating gene, RAG-1
32. V(D)J recombination: molecular biology and regulation
33. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
34. RAG-2 expression is not essential for chicken immunoglobulin gene conversion
35. Somatic generation of antibody diversity
36. Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase