Inhibition of Human Neurotropic Virus (JCV) DNA Replication in Glial Cells by Camptothecin

Virology

Volumn 196, Issue 2, 1993, Pages 612-618

  Kerr, Douglas A ^a   Chang, Chun Fan ^a   Gordon, Jennifer ^a   Bjornsti, Mary Ann ^a   Khalili, Kamel ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; POLYCLONAL ANTIBODY;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CONTROLLED STUDY; GLIA CELL; HUMAN; HUMAN TISSUE; JC VIRUS; NONHUMAN; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; VIRUS REPLICATION;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA REPLICATION; DNA TOPOISOMERASES, TYPE I; GENE EXPRESSION REGULATION, VIRAL; GLIOMA; HUMAN; JC VIRUS; NEUROGLIA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TOPOTECAN; TRANSFECTION;

EID: 0027430663     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1006/viro.1993.1517     Document Type: Article

References (29)

1. Astrom, K.-E., Mancall, E. L., and Richardson, E. P., (1958). Pro-gressive multifocal leukoencephalopathy: A hitherto unrecog-nized complication of chronic lymphatic leukemia and Hodgkin’s disease. Brain 81, 93-111.
2. Berger, J. R., Kaszovitz, B., Post, J. D., and Dickinson, G. (1987). Progressive multifocal leukoencephalopathy associated with hu-man immunodeficiency virus infection: a review of the literature with a report of sixteen cases. Ann. Int. Med. 107, 78-87.
3. Bjornsti, M.-A. (1991), DNAtopoisomerases. Curr. Opin, Struc. Biol. 1, 99-104.
4. Bjornsti, M.-A., Benedetti, P., Viglianti, G. A., and Wang, J. C. (1989). Expression of human DNA topoisomerase I in yeast cells lacking DNA topoisomerase I: Restriction of sensitivity of the cells to the antitumor drug camptothecin. Can. Res. 49, 6318-6323.
5. Brook, B. R., and Walker, D. L. (1984). Progressive multifocal leuko-encephalopathy. Neurol. Clin. 2, 299-313.
6. Champoux, J. J. (1992). Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are defi-cient in histones. Nucleic Acids Res. 20, 3347-3352.
7. Champoux, J. J. (1990). Mechanistic aspects of type-1 topoisomer- ases. In “DNA Topology and its Biological Effects” (N. Cozzarelli and J. C. Wang, Eds), pp. 217-242. Cold Spring Harbor Labora-tory Press, Cold Spring Harbor, NY.
8. Champoux, J. J. (1988). Topoisomerase I is preferentially associated with isolated replicating simian virus 40 molecules after treatment of infected cells with camptothecin. J. Virol. 62, 3675-3683.
9. D’Arpa, P., and Liu, L. (1989). Topoisomerase-targeting antitumor drugs. Biochim. Biophys. Acta 989, 163-177.
10. Feigenbaum, L., Khalili, K., Major, E. O., and Khoury, G. (1987). Regulation of the host range of human papovavirus JCV. Proc. Natl. Acad. Sci. USA 84, 3695-3698.
11. Frisque, R. J., Bream, G. L., and Cannella, M. T. (1984). Human polyomavirus JC virus genome. J. Virol. 51, 458-469.
12. Gorman, C. M., Moffat, L. F., and Howard, B. H. (1982). Recombi-nant genomes which express chloramphenicol acetyl transferase in mammalian cells. Mol. Cell. Biol. 2, 1044-1051.
13. Graham, F., and Van der Eb, A. (1973). A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52, 456-467.
14. Hirt, B. (1967). Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biot. 26, 365-369.
15. Jaxel, C., Kohn, K., and Pommier, Y. (1988). Topoisomerase I inter-action with SV40 DNA in the presence and absence of camptothe-cin. Nucleic Acids Res. 16, 11157-11162.
16. Khalili, K., Rappaport, J., and Khoury, G. (1988). Nuclear factors in human brain cells bind specifically to the JCV regulatory region. EMBOJ. 7, 1205-1210.
17. Kenney, S., Natarajan, V., Strika, V., Khoury, G., and Salzman, N. P. (1984). JC virus enhancer-promoter active in human brain cells. Science 226, 1337-1339.
18. Lashgari, M., Tada, H., Amini, S., and Khalili, K. (1989). Regulation of JCVL promoter function. Transactivation of JCVL promoter by JCV and SV40 early proteins. Virology 170, 292-295.
19. Liu, L. F. (1989). DNA topoisomerases as antitumor drugs. Anna. Rev. Biochem. 58, 351-375.
20. Luckow, B., and Schultz, G. (1987). CAT constructions with multi-ple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res. 15, 5490-5498.
21. Major, E. O., Amemiya, K., Tornatore, C., Houff, S. A., and Berger, J. R. (1992). Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinat-ing disease of the human brain. Clin. Microbiology Reviews 5, 49-73.
22. Maniatis, T., Fritsch, E. F., and Sambrook, T. (1982). “Molecular Cloning: A Laboratory Manual.” Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
23. Priel, E., Showalter, S. D., and Blair, D. G. (1991). Inhibition of human immunodeficiency virus (HIV-1) replication in vitro by non- cytotoxic doses of camptothecin, a topoisomerase I inhibitor. AIDS Res. Human Retroviruses 7, 65-72.
24. Queen, C., and Baltimore, D. (1983). Immunoglobulin gene tran-scription is activated by downstream sequence elements. Ceil 33, 741-748.
25. Richardson, E. P. (1961), Progressive multifocal leukoencephalopa-thy. N. Engl. J. Med. 265, 815-823.
26. Tada, H., and Khalili, K. (1992). A novel sequence-specific DNA- binding protein, LCP-1, interacts with single stranded DNA and differentially regulates early gene expression of the human neuro-tropic JC virus. J. Virol. 66, 6885-6892.
27. Tada, H., Ushgari, M., Rappaport, J., and Khalili, K. (1989). Cell type-specific expression of JC virus early promoter is determined by positive and negative regulation. J. Virol. 63, 463-466.
28. Walker, D. L. (1985). Progressive multifocal leukoencephalopathy. In “Handbook of Clinicai Neurology” (P. J. Vinken, etal., Eds), Vol. 47, pp. 503-524. Elsevier, New York.
29. Wang, J. C., and Liu, L. F. (1990). DNA replication: topological aspects and the roles of DNA topoisomerases. In “DNA Topology and its Biological Effects” (N. Cozzarelli andJ. C. Wang, Eds), pp. 321-340. Cold Spring Harbor Laboratory Press, Cold Spring Har-bor, NY.