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Volumn 168, Issue 5, 1993, Pages 1148-1156

Inhibition of the Protease of Human Immunodeficiency Virus Blocks Replication and Infectivity of the Virus in Chronically Infected Macrophages

Author keywords

[No Author keywords available]

Indexed keywords

1 (NAPHTHOXYACETYL)HISTIDYL(5 AMINO 6 CYCLOHEXYL 3,4 DIHYDROXY 2 ISOPROPYLHEXANOYL)ISOLEUCINE N (2 PYRIDYLMETHYL)AMIDE; ALPHA INTERFERON; ANTISENSE OLIGODEOXYNUCLEOTIDE; PROTEINASE INHIBITOR; ZIDOVUDINE;

EID: 0027430147     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/168.5.1148     Document Type: Article
Times cited : (38)

References (63)
  • 1
    • 0022640412 scopus 로고
    • Administration of 3'azido- 3'-deoxythymidine, an inhibitor ofHTLV-III/LAV replication, to patients with AIDS or AIDS-related complex
    • Yarchoan R, Klecker RW, Weinhold KJ, Administration of 3'azido- 3'-deoxythymidine, an inhibitor ofHTLV-III/LAV replication, to patients with AIDS or AIDS-related complex, Lancet 1986; 1: 575-82.
    • (1986) Lancet , vol.1 , pp. 575-582
    • Yarchoan, R.1    Klecker, R.W.2    Weinhold, K.J.3
  • 2
    • 0023268502 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Fischl MA, Richman DD, Grieco MH, The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex, N Engl 1 Med 1987; 317: 185-90.
    • (1987) N Engl 1 Med , vol.317 , pp. 185-190
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3
  • 3
    • 0024349612 scopus 로고
    • In vivo activity against HIV and favorable toxicity profile of 2', 3'-dideoxyinosine
    • Yarchoan R, Mitsuya H, Thomas RV, In vivo activity against HIV and favorable toxicity profile of 2', 3'-dideoxyinosine, Science 1989; 245: 412-7.
    • (1989) Science , vol.245 , pp. 412-417
    • Yarchoan, R.1    Mitsuya, H.2    Thomas, R.V.3
  • 4
    • 0001707601 scopus 로고
    • 3'-azido-3'-deoxythymidine (BW A509U): An antiviral agent that inhibits the infectivity and cytopathic effect of human T Iymphotropic virus type III-lymphadenopathy associated virus in vitro
    • Mitsuya H, Weinhold KJ, Furman PA, 3'-azido-3'-deoxythymidine (BW A509U): An antiviral agent that inhibits the infectivity and cytopathic effect of human T Iymphotropic virus type III-lymphadenopathy associated virus in vitro, Proc Natl Acad Sci USA 1985; 82: 7096-101.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7096-7101
    • Mitsuya, H.1    Weinhold, K.J.2    Furman, P.A.3
  • 5
    • 0022996630 scopus 로고
    • Phosphorylation of3'-azido-3'deoxythymidine and selective interaction ofthe 5'-triphosphate with human immunodeficiency virus reverse transcriptase
    • Furman PA, Fyfe JA, St Clair M, Phosphorylation of3'-azido-3'deoxythymidine and selective interaction ofthe 5'-triphosphate with human immunodeficiency virus reverse transcriptase, Proc Natl Acad Sci USA 1986; 83: 8333-7.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8333-8337
    • Furman, P.A.1    Fyfe, J.A.2    St Clair, M.3
  • 6
    • 0025987078 scopus 로고
    • Antiretroviral therapy of HIV infection: Current strategies and challenges for the future
    • Yarchoan R, Pluda JM, Perno CF, Mitsuya H, Broder S, Antiretroviral therapy of HIV infection: Current strategies and challenges for the future, Blood 1991; 78: 859-84.
    • (1991) Blood , vol.78 , pp. 859-884
    • Yarchoan, R.1    Pluda, J.M.2    Perno, C.F.3    Mitsuya, H.4    Broder, S.5
  • 7
    • 0025186450 scopus 로고
    • Molecular targets for AIDS therapy
    • Mitsuya H, Yarchoan R, Broder S, Molecular targets for AIDS therapy, Science 1990; 249: 1533-44.
    • (1990) Science , vol.249 , pp. 1533-1544
    • Mitsuya, H.1    Yarchoan, R.2    Broder, S.3
  • 9
    • 0022551277 scopus 로고
    • Infection ofmonocytes/macrophages by human T-Iymphotropic virus type III
    • Ho DD, Rota TR, Hirsch MS, Infection ofmonocytes/macrophages by human T-Iymphotropic virus type III, J C1in Invest 1986; 77: 1712-5.
    • (1986) J C1in Invest , vol.77 , pp. 1712-1715
    • Ho, D.D.1    Rota, T.R.2    Hirsch, M.S.3
  • 10
    • 0023785829 scopus 로고
    • Inhibition of human immunodeficiency virus (HIV-I /HTLV-IIIBa-d replication in fresh and cultured human peripheral blood monocytes/rnacrophages by azidothymidine and related 2', 3'-dideoxynucleosides
    • Perno CF, Yarchoan R, Cooney DA, Inhibition of human immunodeficiency virus (HIV-I /HTLV-IIIBa-d replication in fresh and cultured human peripheral blood monocytes/rnacrophages by azidothymidine and related 2', 3'-dideoxynucleosides, J Exp Med 1988; 168: 1111-25.
    • (1988) J Exp Med , vol.168 , pp. 1111-1125
    • Perno, C.F.1    Yarchoan, R.2    Cooney, D.A.3
  • 11
    • 0022522203 scopus 로고
    • Detection of AIDS virus in macro phages in brain tissues from AIDS patients with encephalopathy
    • Koenig S, Gendelman HE, Orenstein JM, Detection of AIDS virus in macro phages in brain tissues from AIDS patients with encephalopathy, Science 1986; 233: I089-92.
    • (1986) Science , vol.233 , pp. 1089-1192
    • Koenig, S.1    Gendelman, H.E.2    Orenstein, J.M.3
  • 12
    • 0023106840 scopus 로고
    • AIDS subacute encephalitis, Identification of HIV-infected cells
    • Vazeux R, Brousse N, Jarry A, AIDS subacute encephalitis, Identification of HIV-infected cells, Am J Pathol 1986; 126: 403-10.
    • (1986) Am J Pathol , vol.126 , pp. 403-410
    • Vazeux, R.1    Brousse, N.2    Jarry, A.3
  • 14
    • 0021220253 scopus 로고
    • Follicular dendritic cells and virus-like particles in AIDS-related lymphadenopathy
    • Armstrong lA, Horn P, Follicular dendritic cells and virus-like particles in AIDS-related lymphadenopathy, Lancet 1984; 2: 370-2.
    • (1984) Lancet , vol.2 , pp. 370-372
    • Armstrong, L.1    Horn, P.2
  • 15
    • 0023101667 scopus 로고
    • Epidermal Langerhans cells: A target for HTLV-III/LAV infection
    • Tschachler E, Groh V, Popovic M, Epidermal Langerhans cells: A target for HTLV-III/LAV infection, J Invest Dermatol 1987; 88: 233-41.
    • (1987) J Invest Dermatol , vol.88 , pp. 233-241
    • Tschachler, E.1    Groh, V.2    Popovic, M.3
  • 16
    • 0025003118 scopus 로고
    • Macrophages as susceptible targets for HIV infection, persistent viral reservoir in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease
    • Meltzer MS, Nakamura M, Hanse BD, Turpin JA, Kalter DC, Gendelman HE, Macrophages as susceptible targets for HIV infection, persistent viral reservoir in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease, AIDS Res Hum Retroviruses 1990; 6: 967-75.
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 967-975
    • Meltzer, M.S.1    Nakamura, M.2    Hanse, B.D.3    Turpin, J.A.4    Kalter, D.C.5    Gendelman, H.E.6
  • 17
    • 0005015528 scopus 로고
    • Mononuclear phagocytes of blood and bone marrow: Comparative roles as viral reservoirs in human immunodeficiency virus type I infection
    • McElrath MJ, Pruett JE, Cohn ZA, Mononuclear phagocytes of blood and bone marrow: Comparative roles as viral reservoirs in human immunodeficiency virus type I infection, Proc Natl Acad Sci USA 1989; 86: 675-9.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 675-679
    • McElrath, M.J.1    Pruett, J.E.2    Cohn, Z.A.3
  • 19
    • 0026522445 scopus 로고
    • HIV-I in monocytes: Frequency of detection of proviral DNA using PCR and comparison with the total CD4 count
    • Innocenti P, Ottman M, Morand P, Leclercq P, Seigneurin JM, HIV-I in monocytes: Frequency of detection of proviral DNA using PCR and comparison with the total CD4 count, AIDS Res Hum Retroviruses 1992; 8: 261-8.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , pp. 261-268
    • Innocenti, P.1    Ottman, M.2    Morand, P.3    Leclercq, P.4    Seigneurin, J.M.5
  • 20
    • 0025342066 scopus 로고
    • Infection ofmonocytes by human immunodeficiency virus type-I is blocked by inhibitors of CD4-gp 120 binding, even in the presence ofenhancing antibodies
    • Perno CF, Baseler MW, Broder S, Yarchoan R, Infection ofmonocytes by human immunodeficiency virus type-I is blocked by inhibitors of CD4-gp 120 binding, even in the presence ofenhancing antibodies, J Exp Med 1990; 171: 1043-56.
    • (1990) J Exp Med , vol.171 , pp. 1043-1056
    • Perno, C.F.1    Baseler, M.W.2    Broder, S.3    Yarchoan, R.4
  • 21
    • 0025040517 scopus 로고
    • Ability of anti-HIV agents to inhibit HIV replication in rnonocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HlV antibodies
    • Perno CF, Cooney DA, Currens MJ, Ability of anti-HIV agents to inhibit HIV replication in rnonocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HlV antibodies, AIDS Res Hum Retroviruses 1990; 6: 1051-8.
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 1051-1058
    • Perno, C.F.1    Cooney, D.A.2    Currens, M.J.3
  • 22
    • 0025090578 scopus 로고
    • Full-length recombinant CD4 and recombinant gp 120 inhibit fusion between HIV-infected macrophages and uninfected CD4-expressing T-Iymphoblastoid cells
    • Crowe S, Mills J, Kirihara J, Boothman J, Marshall JA, McGrath MS, Full-length recombinant CD4 and recombinant gp 120 inhibit fusion between HIV-infected macrophages and uninfected CD4-expressing T-Iymphoblastoid cells, AIDS Res Hum Retroviruses 1990; 6: 1031-7.
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 1031-1037
    • Crowe, S.1    Mills, J.2    Kirihara, J.3    Boothman, J.4    Marshall, J.A.5    McGrath, M.S.6
  • 23
    • 0026587543 scopus 로고
    • Cell-to-cell spread ofHIVI occurs within minutes and may not involve the participation of virus particles
    • Sato H, Orenstein J, Dimitrov D, Martin M, Cell-to-cell spread ofHIVI occurs within minutes and may not involve the participation of virus particles, Virology 1992; 186: 712-24.
    • (1992) Virology , vol.186 , pp. 712-724
    • Sato, H.1    Orenstein, J.2    Dimitrov, D.3    Martin, M.4
  • 24
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type I clones at different stages of infection: Progression ofdisease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker H, Koot M, Kootstra NA, Biological phenotype of human immunodeficiency virus type I clones at different stages of infection: Progression ofdisease is associated with a shift from monocytotropic to T-cell-tropic virus population, J Virol 1992; 66: 135-460.
    • (1992) J Virol , vol.66 , pp. 135-460
    • Schuitemaker, H.1    Koot, M.2    Kootstra, N.A.3
  • 25
    • 0025783669 scopus 로고
    • Identification of the envelope V3 loop as the primary determinant ofT-cell tropism in HIV-I
    • Hwang SS, Bojle TJ, Lyerly HK, Cullen BR, Identification of the envelope V3 loop as the primary determinant ofT-cell tropism in HIV-I, Science 1991; 253: 71-4.
    • (1991) Science , vol.253 , pp. 71-74
    • Hwang, S.S.1    Bojle, T.J.2    Lyerly, H.K.3    Cullen, B.R.4
  • 27
    • 0026748688 scopus 로고
    • Human immunodeficiency virus infection in microglia: Correlation between cells infected in the brain and cells cultured from infectious brain tissue
    • Brinkmann R, Schwinn A, Narayan O, Zink C, Kreth HW, Human immunodeficiency virus infection in microglia: Correlation between cells infected in the brain and cells cultured from infectious brain tissue, Ann Neurol 1992; 31: 361-5.
    • (1992) Ann Neurol , vol.31 , pp. 361-365
    • Brinkmann, R.1    Schwinn, A.2    Narayan, O.3    Zink, C.4    Kreth, H.W.5
  • 28
    • 0023898273 scopus 로고
    • Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor I-treated monocytes
    • Gendelman HE, Orenstein JM, Martin MA, Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor I-treated monocytes, J Exp Med 1988; 167: 1428-40.
    • (1988) J Exp Med , vol.167 , pp. 1428-1440
    • Gendelman, H.E.1    Orenstein, J.M.2    Martin, M.A.3
  • 29
    • 0024537623 scopus 로고
    • Replication ofhuman immunodeficiency virus in monocytes: Granulocyte-macrophage colony stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2', 3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine
    • Perno CF, Yarchoan R, Cooney DA, Replication ofhuman immunodeficiency virus in monocytes: Granulocyte-macrophage colony stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2', 3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine, J Exp Med 1989; 169: 933-51.
    • (1989) J Exp Med , vol.169 , pp. 933-951
    • Perno, C.F.1    Yarchoan, R.2    Cooney, D.A.3
  • 30
    • 0026648436 scopus 로고
    • Effects ofbone marrow stimulatory cytokines on HIV replication and the antiviral activity of dideoxynucleosides in cultures of rnonocyte/macrophages
    • Perno CF, Cooney DA, Gao WY, Effects ofbone marrow stimulatory cytokines on HIV replication and the antiviral activity of dideoxynucleosides in cultures of rnonocyte/macrophages, Blood 1992; 80: 995-1003.
    • (1992) Blood , vol.80 , pp. 995-1003
    • Perno, C.F.1    Cooney, D.A.2    Gao, W.Y.3
  • 31
    • 0025012838 scopus 로고
    • Tumor necrosis factor alfa functions in an autocrine manner in the induction ofhuman immunodeficiency virus expression
    • Poli G, Kinter A, Justement JS, Tumor necrosis factor alfa functions in an autocrine manner in the induction ofhuman immunodeficiency virus expression, Proc Natl Acad Sci USA 1990; 87: 782-5.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 782-785
    • Poli, G.1    Kinter, A.2    Justement, J.S.3
  • 32
    • 0026517811 scopus 로고
    • Recombinant interleukin-4 (IL-4) stimulates human immunodeficiency virus production by infected monocytes and macrophages
    • Kazazi F, Mathjis JM, Chang J, Recombinant interleukin-4 (IL-4) stimulates human immunodeficiency virus production by infected monocytes and macrophages, J Gen Virol 1992; 73: 941-9.
    • (1992) J Gen Virol , vol.73 , pp. 941-949
    • Kazazi, F.1    Mathjis, J.M.2    Chang, J.3
  • 33
    • 0026515054 scopus 로고
    • Different pattern ofactivity of inhibitors ofthe human immunodeficiency virus in lymphocytes and monocyte/rnacrophages
    • Perno CF, Yarchoan R, Balzarini J, Different pattern ofactivity of inhibitors ofthe human immunodeficiency virus in lymphocytes and monocyte/rnacrophages, Antiviral Res 1992; 17: 289-304.
    • (1992) Antiviral Res , vol.17 , pp. 289-304
    • Perno, C.F.1    Yarchoan, R.2    Balzarini, J.3
  • 34
    • 0026579208 scopus 로고
    • The HIV-I protease as a therapeutic target for AIDS
    • Debouck C, The HIV-I protease as a therapeutic target for AIDS, AIDS Res Hum Retroviruses 1992; 8: 153-64.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , pp. 153-164
    • Debouck, C.1
  • 35
    • 0025169561 scopus 로고
    • An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection
    • Ashorn P, McQuade TJ, Thaisrivongs S, Tomasselli AG, Tarpley WG, Moss B, An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection, Proc Natl Acad Sci USA 1990; 87: 7472-6.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7472-7476
    • Ashorn, P.1    McQuade, T.J.2    Thaisrivongs, S.3    Tomasselli, A.G.4    Tarpley, W.G.5    Moss, B.6
  • 36
    • 0026561407 scopus 로고
    • Recent advances in the design of HIV proteinase inhibitors
    • Martin JA, Recent advances in the design of HIV proteinase inhibitors, Antiviral Res 1992; 17: 265-78.
    • (1992) Antiviral Res , vol.17 , pp. 265-278
    • Martin, J.A.1
  • 37
    • 0026763251 scopus 로고
    • In vitro inhibition of human immunodeficiency virus (HIV) type I replication by C2 symmetry- based HlV protease inhibitors as single agents or in combinations
    • Kageyama S, Weinstein IN, Shirasaka T, In vitro inhibition of human immunodeficiency virus (HIV) type I replication by C2 symmetry- based HlV protease inhibitors as single agents or in combinations, Antimicrob Agents Chemother 1992; 36: 926-33.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 926-933
    • Kageyama, S.1    Weinstein, I.N.2    Shirasaka, T.3
  • 38
    • 0005241362 scopus 로고
    • Active human immunodeficiency virus protease is required for viral infectivity
    • Kohl H, Emini E, Schleif W, Active human immunodeficiency virus protease is required for viral infectivity, Proc Natl Acad Sci USA 1988; 85: 4686-90.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4686-4690
    • Kohl, H.1    Emini, E.2    Schleif, W.3
  • 39
    • 0023189868 scopus 로고
    • A structural model of the retroviral proteases
    • Pearl L, Taylor W, A structural model of the retroviral proteases, Nature 1987; 329: 351-4.
    • (1987) Nature , vol.329 , pp. 351-354
    • Pearl, L.1    Taylor, W.2
  • 40
    • 0021237243 scopus 로고
    • Detection, isolation, and continuous production of cytopathic retroviruses (HTLVlll) from patients with AIDS and pre-AIDS
    • Popovic M, Sangaradharan MG, Read E, Gallo RC, Detection, isolation, and continuous production of cytopathic retroviruses (HTLVlll) from patients with AIDS and pre-AIDS, Science 1984; 224: 497-501.
    • (1984) Science , vol.224 , pp. 497-501
    • Popovic, M.1    Sangaradharan, M.G.2    Read, E.3    Gallo, R.C.4
  • 41
    • 0024212313 scopus 로고
    • Synthesis of phosphorothioate analogues of oligodeoxynucleosides and its antiviral activity against human immunodeficiency virus (HIV)
    • Matsukura M, Zon G, Shinozuka K, Synthesis of phosphorothioate analogues of oligodeoxynucleosides and its antiviral activity against human immunodeficiency virus (HIV), Gene 1988; 72: 343-7.
    • (1988) Gene , vol.72 , pp. 343-347
    • Matsukura, M.1    Zon, G.2    Shinozuka, K.3
  • 42
    • 0000600241 scopus 로고
    • Regulation of viral expression of HIV (Human immunodeficiency virus) in vitro by antisense phosphorothioate oligodeoxynucleosides against rev (art/trs) in chronically infected cells
    • Matsukura M, Zon G, Shinozuka K, Regulation of viral expression of HIV (human immunodeficiency virus) in vitro by antisense phosphorothioate oligodeoxynucleosides against rev (art/trs) in chronically infected cells, Proc Natl Acad Sci USA 1989; 86: 4244-8.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4244-4248
    • Matsukura, M.1    Zon, G.2    Shinozuka, K.3
  • 43
    • 0026351522 scopus 로고
    • Phosphorothioate oligonucleotides: Chemistry, purification, analysis, scale-up and future directions
    • Zon G, Geiser TG, Phosphorothioate oligonucleotides: Chemistry, purification, analysis, scale-up and future directions, Anticancer Drug Des 1991; 6: 539-68.
    • (1991) Anticancer Drug Des , vol.6 , pp. 539-568
    • Zon, G.1    Geiser, T.G.2
  • 44
    • 0025811531 scopus 로고
    • Duplex stabilities of phosphorothioate, methylphosphonate, and RNA analogs of two DNA 14-mers
    • Kibler-Herzog L, Zon G, Uznanski B, Whittier G, Wilson WD, Duplex stabilities of phosphorothioate, methylphosphonate, and RNA analogs of two DNA 14-mers, Nucleic Acids Res 1991; 19: 2979-86.
    • (1991) Nucleic Acids Res , vol.19 , pp. 2979-2986
    • Kibler-Herzog, L.1    Zon, G.2    Uznanski, B.3    Whittier, G.4    Wilson, W.D.5
  • 45
  • 46
    • 0023687234 scopus 로고
    • Rapid and automated tetrazoliurn- based colorimetric assay for the detection of anti-HlV compounds
    • Pauwels R, Balzarini J, Baba M, Rapid and automated tetrazoliurn- based colorimetric assay for the detection of anti-HlV compounds, J Virol Methods 1988; 20: 309-21.
    • (1988) J Virol Methods , vol.20 , pp. 309-321
    • Pauwels, R.1    Balzarini, J.2    Baba, M.3
  • 47
    • 0026476725 scopus 로고
    • A tetrazolium-based colorimetric assay for quantification of HIV-induced cytopathogenicity in monocyte-macrophages exposed to macrophage-colony stimulating factor
    • Bergamini A, Perno CF, Capozzi M, A tetrazolium-based colorimetric assay for quantification of HIV-induced cytopathogenicity in monocyte-macrophages exposed to macrophage-colony stimulating factor, J Virol Methods 1992; 40: 275-86.
    • (1992) J Virol Methods , vol.40 , pp. 275-286
    • Bergamini, A.1    Perno, C.F.2    Capozzi, M.3
  • 49
    • 0001865121 scopus 로고
    • Detection ofhuman immunodeficiency virus
    • Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds, San Diego: Academic Press
    • Kellogg DE, Kwok S, Detection ofhuman immunodeficiency virus, In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds, PCR protocols: A guide to methods and applications, San Diego: Academic Press, 1990: 337-47.
    • (1990) PCR Protocols: A Guide to Methods and Applications , pp. 337-347
    • Kellogg, D.E.1    Kwok, S.2
  • 50
    • 0026708188 scopus 로고
    • Progression of early steps of human immunodeficiency virus type I replication in the presence of an inhibitor of viral protease
    • Jacobsen H, Ahlborn-Laake L, Gugel R, Mous J, Progression of early steps of human immunodeficiency virus type I replication in the presence of an inhibitor of viral protease, J Virol 1992; 66: 5087-91.
    • (1992) J Virol , vol.66 , pp. 5087-5091
    • Jacobsen, H.1    Ahlborn-Laake, L.2    Gugel, R.3    Mous, J.4
  • 51
    • 0023447274 scopus 로고
    • Phosphorothioate analogs of oligodeoxynucleotides: Inhibitors ofreplication and cytopathic effectof human immunodeficiency virus
    • Matsukura M, Shinozuka K, Zon G, Phosphorothioate analogs of oligodeoxynucleotides: Inhibitors ofreplication and cytopathic effectof human immunodeficiency virus, Proc Natl Acad Sci USA 1987; 84: 7706-10.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7706-7710
    • Matsukura, M.1    Shinozuka, K.2    Zon, G.3
  • 52
    • 0026516575 scopus 로고
    • Cohen JS, A comparison ofgag, pol, and rev antisense oligodeoxynuc1eotides as inhibitors of HIV-1
    • Kinchington D, Galpin S, Jaroszewski JW, Ghosh K, Subasinghe C, Cohen JS, A comparison ofgag, pol, and rev antisense oligodeoxynuc1eotides as inhibitors of HIV-1, Antiviral Res 1992; 17: 53-62.
    • (1992) Antiviral Res , vol.17 , pp. 53-62
    • Kinchington, D.1    Galpin, S.2    Jaroszewski, J.W.3    Ghosh, K.4    Subasinghe, C.5
  • 53
    • 0026485009 scopus 로고
    • Specific inhibition of human immunodeficiency virus type I replication by antisense oligonucleotides: An in vitro model for treatment
    • Lisziewicz J, Sun D, Klotman M, Agrawal S, Zamecnik P, Gallo R, Specific inhibition of human immunodeficiency virus type I replication by antisense oligonucleotides: An in vitro model for treatment, Proc Natl Acad Sci USA 1992; 89: 11209-13.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11209-11213
    • Lisziewicz, J.1    Sun, D.2    Klotman, M.3    Agrawal, S.4    Zamecnik, P.5    Gallo, R.6
  • 54
    • 0026726455 scopus 로고
    • Interactions between HIVinfected monocytesand the extracellular matrix: HIV-infected monocytes secrete neutral metalloproteases that degrade basement membrane protein matrices
    • Dhawan S, Toro LA, Jones BE, Meltzer MS, Interactions between HIVinfected monocytesand the extracellular matrix: HIV-infected monocytes secrete neutral metalloproteases that degrade basement membrane protein matrices, J Leukoc Bioi 1992; 52: 244-8.
    • (1992) J Leukoc Bioi , vol.52 , pp. 244-248
    • Dhawan, S.1    Toro, L.A.2    Jones, B.E.3    Meltzer, M.S.4
  • 55
    • 0026667575 scopus 로고
    • Interactions between HIV-infected monocytes and the extracellular matrix, Increased capacity of HIVinfected monocytes to adhere to and spread on extracellular matrix associated with changes in extent of virus replication and cytopathic effect in infected cells
    • Dhawan S, Vargo M, Meltzer MS, Interactions between HIV-infected monocytes and the extracellular matrix, Increased capacity of HIVinfected monocytes to adhere to and spread on extracellular matrix associated with changes in extent of virus replication and cytopathic effect in infected cells, J Leukoc Biol 1992; 51: 62-9.
    • (1992) J Leukoc Biol , vol.51 , pp. 62-69
    • Dhawan, S.1    Vargo, M.2    Meltzer, M.S.3
  • 57
    • 0025858972 scopus 로고
    • Calcium-free calmodulin is a substrate of proteases from human immunodeficiency viruses I and 2
    • Tomasselli AG, Howe WJ, Hui JO, et al, Calcium-free calmodulin is a substrate of proteases from human immunodeficiency viruses I and 2, Proteins Struct Funct Genet 1991; 10: 1-9.
    • (1991) Proteins Struct Funct Genet , vol.10 , pp. 1-9
    • Tomasselli, A.G.1    Howe, W.J.2    Hui, J.O.3
  • 58
    • 0026327505 scopus 로고
    • Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin-I tl as substrates of the protease from human immunodeficiency virus
    • Tomasselli AG, Hui JO, Adams LD, et al, Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin-I tl as substrates of the protease from human immunodeficiency virus, J Bioi Chern 1991; 266: 14548-53.
    • (1991) J Bioi Chern , vol.266 , pp. 14548-14553
    • Tomasselli, A.G.1    Hui, J.O.2    Adams, L.D.3
  • 59
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian D, Vaca K, Noonan CA, Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1, Science 1990; 250: 1593-6.
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 60
    • 0026772902 scopus 로고
    • Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells
    • Lambert OM, Petteway SR Jr, McDanal CE. et al, Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells, Antimicrob Agents Chemother 1992; 36: 982-8.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 982-988
    • Lambert, O.M.1    Petteway, S.R.2    McDanal, C.E.3
  • 61
    • 0023784225 scopus 로고
    • Selective killing ofHIVinfected cells by recombinant human CD4-Pseudol1lonas exotoxin hybrid protein
    • Chaudhary VK, Mizukami T, Fuerst TR, et al, Selective killing ofHIVinfected cells by recombinant human CD4-Pseudol1lonas exotoxin hybrid protein, Nature 1988; 335: 369-72.
    • (1988) Nature , vol.335 , pp. 369-372
    • Chaudhary, V.K.1    Mizukami, T.2    Fuerst, T.R.3
  • 62
    • 0024226884 scopus 로고
    • HIV-infected cells are killed by CD4-ricin A chain
    • Till MA, Ghetie V, Gregory T, et al, HIV-infected cells are killed by CD4-ricin A chain, Science 1988; 242: 1166-8.
    • (1988) Science , vol.242 , pp. 1166-1168
    • Till, M.A.1    Ghetie, V.2    Gregory, T.3
  • 63
    • 0025852258 scopus 로고
    • Anti-HIV activity of CD4-Pseudolllonas exotoxin on infected primary human lymphocytes and monocyte/rnacrophages
    • Ashorn P, Englund G, Martin MA, Moss B, Berger EA, Anti-HIV activity of CD4-Pseudolllonas exotoxin on infected primary human lymphocytes and monocyte/rnacrophages, J Infect Dis 1991; 163: 703-9.
    • (1991) J Infect Dis , vol.163 , pp. 703-709
    • Ashorn, P.1    Englund, G.2    Martin, M.A.3    Moss, B.4    Berger, E.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.