Role of the Cellular Stress Response in the Biogenesis of Cysteamine‐Induced Astrocytic Inclusions in Primary Culture

Journal of Neurochemistry

Volumn 61, Issue 5, 1993, Pages 1755-1765

  Mydlarski, Marc B ^a,b,c   Liang, Jin‐Jun ^b,c   Schipper, Hyman M ^a,b,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Astrocyt; eat shock protein; eme oxygenase; eroxidase activity; lucose regulated protei; ysteamin

Indexed keywords

GLUCOSE REGULATED PROTEIN; HEAT SHOCK PROTEIN; HEME OXYGENASE; HYDROGEN PEROXIDE; MERCAPTAMINE; PEROXIDASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BIOGENESIS; CELL GRANULE; CELL INCLUSION; CELL ORGANELLE; CONTROLLED STUDY; CYTOTOXICITY; GLIA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOCHEMISTRY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; NERVE DEGENERATION; NEWBORN; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; STRESS;

ANIMAL; ANIMALS, NEWBORN; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CYSTEAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEAT-SHOCK PROTEINS; HEME OXYGENASE (DECYCLIZING); HYDROGEN PEROXIDE; INCLUSION BODIES; KINETICS; MOLECULAR WEIGHT; NERVE TISSUE PROTEINS; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T;

EID: 0027424799     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1993.tb09813.x     Document Type: Article

References (59)

1. Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes
2. Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells
3. Purification and characterization of the small 28 kd mammalian stress protein
4. Ovary‐dependent degeneration in the hypothalamic arcuate nucleus
5. Effects of long‐term androgen and estradiol exposure on the hypothalamus
6. Oxidative stress and heat shock protein induction in human cells
7. Induction of HSP27 phosphorylation and thermoresistance in Chinese hamster cells by arsenite, cy‐cloheximide, A23187 and EGTA
8. Oxidative injury and the heat shock response
9. Heme oxygenase is a heat shock protein and PEST protein in rat astroglial cells
10. Thermolabil‐ity of ubiquitin‐activating enzyme from the mammalian cell cycle mutant ts85
11. Structural and microspectrofluorometric studies on glial cells from the peri‐ventricular and arcuate nuclei of the rat hypothalamus
12. Glucose regulated protein induction and cellular resistance to oxidative stress mediated by porphyrin photosensitization
13. The antioxidant activity of haptoglobin towards hemoglobin‐stimulated lipid peroxidation
14. Re‐examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
15. r 27,000 heat shock protein
16. Distribution of endogenous diaminobenzidine‐staining cells in the normal rat brain
17. Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32‐kDa stress protein in normal human skin fibroblasts
18. Heme oxygenase is the major 32‐kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite
19. Detection of neuroteratogens with an in vitro cytotoxicity assay using primary monolayers cultured from dissociated foetal rat brains
20. Mammalian heat shock proteins: an overview with a systems perspective
21. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
22. Ethanol induced tolerance to heat and to adriamycin
23. Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts
24. Expression of human hsp70 in rat fibroblasts enhances cell survival and facilitates recovery from translational and transcriptional inhibition following heat shock
25. Protein measurements with the Folin phenol reagent
26. Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P‐450 is not essential for this enzyme activity
27. Cobalt stimulation of heme degradation in the liver
28. An automated colorimetric microassay for neuronotrophic factors
29. Iron content correlates with peroxidase activity in cysteamine‐induced as‐troglial organelles
30. The generation of superoxide radical during the autoxidation of hemoglobin
31. The stress response, function of the proteins, and perspectives
32. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays
33. Nucleotide sequence and organization of the rat heme oxygenase gene
34. Transport of tetrapyr‐roles by proteins
35. Toxicity of thiols and disulphides: involvement of free‐radical species
36. Stress protein co‐localization to autofluorescent astrocytic inclusions in situ and in cysteamine‐treated glial cultures
37. Comparison of the heat shock response in cultured cortical neurons and astrocytes
38. Cytoplasmic heat shock granules are formed from precursor particles and are associated with a specific set of mRNAs
39. Cisplatin induces the small heat shock protein HSP25 and thermotolerance in Ehrlich ascites tumor cells
40. Activation of heat‐shock genes in eukary‐otes
41. Speculations on the functions of the major heat shock and glucose‐regulated proteins
42. The role of heme oxygenase and aryl hydrocarbon hydroxylase in the protection by cysteamine from acetaminophen hepatotoxicity
43. Gomori‐positive astrocytes: biological properties and implications for neurologic and neuroendocrine disorders
44. Identification of peroxidase‐positive astrocytes by combined histochemical and immunolabeling techniques in situ and in cell culture
45. Role of the gonads in the histologic aging of the hypothalamic arcuate nucleus
46. Glial peroxidase activity in the hypothalamic arcuate nucleus: effects of estradiol valerate‐induced persistent estrus
47. Gomori‐positive astrocytes in primary culture: effects of in vitro age and cysteamine exposure
48. Catechol oxidation by peroxidase‐positive astrocytes in primary culture: an electron spin resonance study
49. Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts
50. Periventricular Gomori‐positive glia in brains of X‐irradiated rats
51. A system of periventricular glia in brain characterized by large peroxisome‐like organelles
52. Induction of haem oxygenase as a defence against oxidative stress
53. Microsomal heme oxygenase: characterization of the enzyme
54. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
55. Nuclear and nucleolar location of the 72000‐dalton heat shock protein in heat‐shocked mammalian cells
56. Cellular and biochemical events in mammalian cells during and after recovery from physiological stress
57. +2 ionophore regulated proteins
58. Transient activation of a distinct serine protein kinase is responsible for 27‐kDa heat shock protein phosphorylation in nitrogen‐stimulated and heat‐shocked cells