Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir

Neurosurgery

Volumn 32, Issue 4, 1993, Pages 597-603

  Markert, James M ^a,b,c,d   Malick, Amy ^a,b,c,d   Coen, Donald M ^a,b,c,d   Martuza, Robert L ^a,b,c,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Brain neoplasm; Encephalitis; Genetic engineering; Glioma; Herpes simplex

Indexed keywords

ACICLOVIR; GANCICLOVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG SENSITIVITY; GLIOBLASTOMA; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SURVIVAL TIME; VIRUS MUTANT;

ACYCLOVIR; ANIMAL; BRAIN NEOPLASMS; ENCEPHALITIS; FEMALE; GLIOMA; HERPES SIMPLEX; HUMAN; MICE; MICE, NUDE; MUTATION; NEOPLASM TRANSPLANTATION; SIMPLEXVIRUS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0027419624     PISSN: 0148396X     EISSN: 15244040     Source Type: Journal    
DOI: 10.1227/00006123-199304000-00016     Document Type: Article

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