Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf

Biochemical Pharmacology

Volumn 45, Issue 7, 1993, Pages 1373-1386

  Borlakoglu, J T ^a   Scott, A ^b   Henderson, C J ^b   Jenke, H J ^c   Wolf, C R ^b  

^a UNIVERSITY OF READING   (United Kingdom)

^b Iimperial Cancer Research Fund Molecular Pharmacology Group University Department of Biochemistry ^*  (United Kingdom)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROANISOLE; ALDRIN; AMINOPHENAZONE; ANILINE; BENZO[A]PYRENE; CYTOCHROME B5; CYTOCHROME P450 ISOENZYME; DIMETHYLNITROSAMINE; EPOXIDE HYDROLASE; ETHOXYRESORUFIN; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; POLYCHLORINATED BIPHENYL; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; GENE EXPRESSION; IMMUNOBLOTTING; LIVER MICROSOME; MOTHER; NONHUMAN; NORTHERN BLOTTING; PLACENTAL TRANSFER; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; XENOBIOTIC METABOLISM;

ANIMAL; ANIMALS, NEWBORN; AROCLOR 1254; AROCLORS; BODY WEIGHT; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; FETUS; ISOENZYMES; LIVER; MATERNAL-FETAL EXCHANGE; ORGAN WEIGHT; PREGNANCY; PROTO-ONCOGENE PROTEIN P21(RAS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T;

EID: 0027418742     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(93)90035-U     Document Type: Article

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