Human liver microsomal cytochrome P450 3A isozymes mediated vindesine biotransformation. Metabolic drug interactions

Biochemical Pharmacology

Volumn 45, Issue 4, 1993, Pages 853-861

  Zhou, Xiao Jian ^a,b   Zhou Pan, Xin Ru ^a,b   Gauthier, Thérése ^a   Placidi, Michel ^a   Maurel, Patrick ^a   Rahmani, Roger ^a  

^a INSERM   (France)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE; ANTINEOPLASTIC AGENT; BENZO[A]PYRENE; CISPLATIN; CYCLOSPORIN A; CYTARABINE; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE; DOPAMINE; DOXORUBICIN; ERYTHROMYCIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; HEXOBARBITAL; LOMUSTINE; METHOTREXATE; MITOXANTRONE; NAVELBINE; NIFEDIPINE; QUINIDINE; SPARTEINE; TENIPOSIDE; THEOPHYLLINE; TROLEANDOMYCIN; VINBLASTINE; VINCRISTINE; VINDESINE;

ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; DRUG INTERACTION; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; LIVER MICROSOME; MICHAELIS MENTEN KINETICS; ORGAN DONOR; PRIORITY JOURNAL;

ADULT; ANTIBODIES; BIOTRANSFORMATION; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DOXORUBICIN; DRUG DESIGN; DRUG INTERACTIONS; FEMALE; HUMAN; ISOENZYMES; KINETICS; LOMUSTINE; MALE; MICROSOMES, LIVER; MIDDLE AGE; MIXED FUNCTION OXYGENASES; SUPPORT, NON-U.S. GOV'T; TENIPOSIDE; VINDESINE;

EID: 0027415546     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(93)90169-W     Document Type: Article

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