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Volumn 34, Issue 6, 1993, Pages 931-934

N-Bromosuccinimide/Dibromodimethylhydantoin in aqueous base: A practical method for the bromination of activated benzoic acids

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID DERIVATIVE; ORGANOBROMINE DERIVATIVE; REMOXIPRIDE;

EID: 0027414966     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)77457-0     Document Type: Article
Times cited : (96)

References (30)
  • 13
    • 84984194235 scopus 로고
    • Liquid Chromatography on Triacetycellulose, 14 Chromatographic Separation of Enantiomers and Barriers to Enantiomerization of Axially Chiral Aromatic Carboxamides
    • (1987) Chemische Berichte , vol.120 , pp. 803
    • Cuyegkeng1    Mannschreck2
  • 15
    • 33747857518 scopus 로고
    • Brominations withN-Bromosuccinimide and Related Compounds. The Wohl-Ziegler Reaction.
    • (1948) Chemical Reviews , vol.43 , pp. 271
    • Djerassi1
  • 18
    • 84918750994 scopus 로고    scopus 로고
    • During the pilot plant run of this reaction, we observed that <1 mole % of the 2,6-DMBA is converted into 2-bromo-1,3-dimethoxybenzene, the result of a decarboxylative bromination.
  • 25
    • 84918748483 scopus 로고    scopus 로고
    • 6): δ 173.75, 173.55, 173.09, 153.09, 34.79, 33.93, 30.45, 27.92. mp 190–1 °C.
  • 26
    • 84918762505 scopus 로고    scopus 로고
    • 2) was minimized with [[Truncated]]
  • 30
    • 84918751688 scopus 로고    scopus 로고
    • An probe experiment was performed using N-chlorosuccinimide (NCS) in place of NBS under identical conditions, except that the reaction was aged at 23–25°C for 19 h instead of 5 h, employing the direct precipitation method. The isolated product showed 59.4 A% 3-chloro-2,6-dimethoxybenzoic acid and 38.6 A% unreacted DMBA.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.