Modulation of liver-specific transcription by interactions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close apposition

Molecular and Cellular Biology

Volumn 13, Issue 4, 1993, Pages 2401-2410

  Jackson, David A ^a   Rowader, Kathleen E ^a   Stevens, Kimberly ^a   Jiang, Chengyu ^a   Milos, Patrice ^a   Zaret, Kenneth S ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR I; SERUM ALBUMIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; DNA BINDING; DNA SEQUENCE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; LIVER CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; TATA BOX; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

BASE SEQUENCE; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; IN VITRO; LIVER; MACROMOLECULAR SYSTEMS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OLIGODEOXYRIBONUCLEOTIDES; SERUM ALBUMIN; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0027408752     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.13.4.2401     Document Type: Article

References (60)

1. Bender, A., and G. F. Sprague, Jr. 1987. MATαt1 protein, a yeast transcription activator, binds synergistically to a set of cell-type-specific genes. Cell 50:681-691.
2. Ben-Levy, R., O. Faktor, I. Berger, and Y. Shaul. 1989. Cellular factors that interact with the hepatitis B virus enhancer Mol. Cell. Biol. 9:180-1809.
3. Bissell, D. M., J. M. Caron, L. E. Babiss, and J. M. Friedman. 1990. Transcriptional regulation of the albumin gene in cultured rat hepatocytes: role of basement membrane matrix. Mol. Biol Med. 7:187-197.
4. Boissier, F., C. Auge-Gouillou, E. Schaeffer, and M. Zakin. 1991. The enhancer of the human transferrin gene is organized in two structural and functional domains. J. Biol. Chem. 266:9822-9828.
5. Borgmeyer, U., J. Nowock, and A. E. Sippel. 1984. The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded DNA. Nucleic Acids Res. 12:4295-4311.
6. Cao, Z., R. M. Umek, and S. L. McKnight. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538-1552.
7. Caron, J. M. 1990. Induction of albumin gene transcription in hepatocytes by extracellular matrix proteins. Mol. Cell. Biol. 10:1239-1243.
8. Cascio, S., and K. S. Zaret. 1991. Hepatocyte differentiation initiates during endodermal-mesenchymal interactions prior to liver formation. Development 113:217-225.
9. Clayton, D. F., and J. E. Darnell, Jr. 1983. Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol. Cell. Biol. 3:1552-1561.
10. Costa, R. H., D. R. Grayson, and J. E. Darnell, Jr. 1989. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antitrypsin genes. Mol. Cell. Biol. 9:1415-1425.
11. Descombes, P., M. Chojkier, M. Lichtsteiner, E. Falvey, and U. Schibler. 1990. LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev. 4:1541-1551.
12. Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
13. Dipersio, C. M., D. A. Jackson, and K. S. Zaret. 1991. The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Mol. Cell. Biol. 11:4405-4414.
14. Drewes, T., L. Klein-Hitpass, and G. U. Ryffel. 1991. Liver specific transcription factors of the HNF3, C/EBP, and LFB1 families interact with the A-activator binding site. Nucleic Acids Res. 23:6383-6389.
15. Enat, R., D. M. Jefferson, N. Ruiz-Opazo, Z. Gatmaitan, L. A. Leinwand, and L. M. Reid. 1984. Hepatocyte proliferation in vitro: its dependence on the use of serum-free, hormonally defined medium and substrata of extracellular matrix. Proc. Natl. Acad. Sci. USA 81:1411-1415.
16. Fritton, H. P., A. E. Sippel, and T. Igo-Kemenes. 1983. Nuclease-hypersensitive sites in the chromatin domain of the chick lysozyme gene. Nucleic Acids Res. 11:3467-3485.
17. Georgoff, I., T. Scott, and H. C. Isom. 1984. Effect of simian virus 40 infection on albumin production by hepatocytes cultured in chemically defined medium and plated on collagen and non-collagen attachment surfaces. J. Biol. Chem. 259:9595-9602.
18. Gil, G., J. R. Smith, J. L. Goldstein, C. A. Slaughter, K. Orth, M. S. Brown, and T. F. Osborne. 1988. Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase. Proc. Natl. Acad. Sci. USA 85:8963-8967.
19. Gloss, B., G. M. Yeo, M. Meisterernst, L. Rogge, E.-L. Winnacker, and H. U. Bernard. 1989. Clusters of nuclear factor I binding sites identify enhancers of several papilloma viruses but alone are not sufficient for enhancer function. Nucleic Acids Res. 17:3519-3533.
20. Godbout, R., R. S. Ingram, and S. M. Tilghman. 1988. Fine structure mapping of the three mouse α-fetoprotein gene enhancers. Mol. Cell. Biol. 8:1169-1178.
21. Gorski, K., M. Carneiro, and U. Schibler. 1986. Tissue specific in vitro transcription from the mouse albumin promoter. Cell 47:767-776.
22. Grange, T., J. Roux, G. Rigaud, and R. Pictet. 1991. Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor. Nucleic Acids Res. 19:131-139.
23. Graves, R. A., P. Tontonoz, S. R. Ross, and B. M. Spiegelman. 1991. Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor. Genes Dev. 5:428-437.
24. Herbst, R. S., N. Friedman, J. E. Darnell, Jr., and L. E. Babiss. 1989. Positive and negative regulatory elements in the mouse albumin enhancer. Proc. Natl. Acad. Sci. USA 86:1553-1557.
25. Hu, J.-M., S. A. Camper, S. M. Tilghman, T. Miller, I. Georgoff, R. Serra, and H. C. Isom. 1992. Functional analyses of albumin expression in a series of hepatocyte cell lines and in primary hepatocytes. Cell Growth Differ. 3:577-588.
26. Jackson, D. A., K. E. Rowader, and K. S. Zaret. Unpublished data.
27. Jackson, P. D., T. Evans, J. M. Nickol, and G. Felsenfeld. 1989. Developmental modulation of protein binding to beta-globin regulatory sites within chicken regulatory loci. Genes Dev. 3:1860-1873.
28. Jantzen, H. M., U. Strahle, B. Gloss, F. Stewart, W. Schmid, M. Boshart, R. Miksicek, and G. Schutz. 1987. Cooperativity of glucocorticoid response elements located far upstream of the tyrosine amino transferase gene. Cell 49:29-38.
29. Kelleher, C. A., C. Goutte, and A. D. Johnson. 1988. The yeast cell-type-specific repressor a2 acts cooperatively with a non-cell-type-specific protein. Cell 53:927-936.
30. Lai, E., V. R. Prezioso, E. Smith, O. Litvin, R. H. Costa, and J. E. Darnell, Jr. 1990. HNF3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev. 4:1427-1436.
31. Lai, E., V. R. Prezioso, W. Tao, W. S. Chen, and J. E. Darnell, Jr. 1991. Hepatocyte nuclear factor 3α belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev. 5:416-427.
32. Lichtsteiner, S., J. Wuarin, and U. Schibler. 1987. The interplay of DNA-binding proteins on the promoter of the mouse albumin gene. Cell 51:963-973.
33. Liu, J.-K., Y. Bergman, and K. S. Zaret. 1988. The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver abundant factors in vitro. Genes Dev. 2:528-541.
34. Liu, J.-K., C. M. DiPersio, and K. S. Zaret. 1991. Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro. Mol. Cell. Biol. 11:773-784.
35. Magnuson, M. A., T. L. Andreone, R. L. Printz, S. Koch, and D. K. Granner. 1989. Rat glucokinase gene: structure and regulation by insulin. Proc. Natl. Acad. Sci. USA 86:4838-4842.
36. Meisterernst, M., L. Rogge, R. Foeckler, M. Karaghiosoff, and E.-L. Winnacker. 1989. Structural and functional organization of a porcine gene coding for nuclear factor I. Biochemistry 28:8191-8200.
37. Mermod, N., E. A. O'Neill, T. J. Kelly, and T. Tjian. 1989. The proline-rich transcriptional activator of CTF/NF-1 is distinct from the replication and DNA binding domain. Cell 48:741-753.
38. Milos, P. M., and K. S. Zaret. 1992. A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro. Genes Dev. 6:991-1004.
39. Nagpal, S., M. Saunders, P. Kastern, B. Durand, H. Nakshatri, and P. Chambon. 1992. Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell 70:1007-1019.
40. Pani, L., D. G. Overdier, A. Porcella, X. Qian, E. Lai, and R. Costa. 1992. Hepatocyte nuclear factor 3β contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein. Mol. Cell. Biol. 12:3723-3732.
41. Pani, L., X. Qian, D. Clevidence, and R. Costa. 1992. The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor 3β involves a cell-specific factor and positive autoactivation. Mol. Cell. Biol. 12:552-562.
42. Paonessa, G., F. Gounari, R. Frank, and R. Cortese. 1988. Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J. 7:3115-3123.
43. Petropoulos, I., C. Auge-Gouillou, and M. M. Zakin. 1991. Characterization of the active part of the human transferrin gene enhancer and purification of two liver nuclear factors interacting with the TGTTTGC motif present in this region. J. Biol. Chem. 266:24220-24231.
44. Pinkert, C. A., D. M. Ornitz, R. L. Brinster, and R. D. Palmiter. 1987. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient liver-specific expression in transgenic mice. Genes Dev. 1:268-276.
45. Powell, D. J., J. M. Friedman, A. J. Oulette, K. S. Krauter, and J. E. Darnell, Jr. 1984. Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver. Mol. Biol. 170:21-35.
46. Rigaud, G., J. Roux, R. Pictet, and T. Grange. 1991. In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Cell 67:977-986.
47. Rupp, R. A. W., U. Kruse, G. Multhaup, U. Gobel, K. Beyreuther, and A. E. Sippel. 1990. Chicken FN1/TGGCA proteins are encoded by at least three independent genes: NF1/A, NF1-B and NF1-C with homologies in mammalian genomes. Nucleic Acids Res. 18:2607-2616.
48. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
49. Santoro, C., N. Mermod, P. C. Andrews, and R. Tjian. 1988. A family of human CAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature (London) 334:218-224.
50. Schmid, P., and W. A. Schulz. 1990. Coexpression of the C-MYC protooncogene with α-fetoprotein and albumin in fetal mouse liver. Differentiation 45:96-102.
51. Shaul, Y., and R. Ben-Levy. 1987. Multiple nuclear proteins in liver cells are bound to hepatitis B virus enhancer element and its upstream sequences. EMBO J. 6:1913-1920.
52. Shiojiri, N., J. M. Lemire, and N. Fausto. 1990. Cell lineages and oval cell progenitors in rat liver development. Cancer Res. 51:2611-2620.
53. 51a.Tanaka, M., J-S. Lai, and W. Herr. 1992. Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter. Cell 68:755-767.
54. Theisen, M., A. Steif, and A. E. Sippel. 1986. The lysozyme enhancer: cell-specific activation of the chicken lysozyme gene by a far-upstream DNA element. EMBO J. 5:719-724.
55. Tilghman, S. M., and A. Belayew. 1982. Transcriptional control of the murine albumin/α-fetoprotein locus during development. Proc. Natl. Acad. Sci. USA 79:5254-5257.
56. Weigel, D., and H. Jackle. 1990. The fork head domain: a novel DNA binding motif of eukaryotic transcription factors. Cell 63:455-456.
57. Widom, R. L., J. A. A. Ladias, S. Kouidou, and S. Karathanasias. 1991. Synergistic interactions between transcription factors control expression of the apolipoprotein Al gene in liver cells. Mol. Cell. Biol. 11:677-687.
58. Williams, S. C., C. A. Cantwell, and P. F. Johnson. 1991. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev. 5:1553-1567.
59. Zaret, K. S., C. M. DiPersio, D. A. Jackson, W. J. Montigny, and D.L. Weinstat. 1988. Conditional enhancement of liver-specific gene transcription. Proc. Natl. Acad. Sci USA 85-9076-9080.
60. Zaret, K. S., J.-k. Liu, and C. M. DiPersio. 1990. Site-directed mutagenesis of the albumin transcriptional enhancer with the polymerase chain reaction. Proc. Natl. Acad. Sci. USA 87: 5469-5473.