Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 90, Issue 5, 1993, Pages 1977-1981

  Strittmatter, Warren J ^a   Saunders, Ann M ^a   Schmechel, Donald ^a   Pericak Vance, Margaret ^a   Enghild, Jan ^a   Salvesen, Guy S ^a   Roses, Allen D ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E;

ALLELE; ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISEASE ASSOCIATION; FAMILIAL DISEASE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LUMBAR PUNCTURE; NEUROPATHOLOGY; ONSET AGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN IMMOBILIZATION; PROTEIN LOCALIZATION;

ALLELES; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMAL; APOLIPOPROTEINS E; BRAIN; GENE FREQUENCY; HUMAN; LEMUR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; SOLUBILITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027407565     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.90.5.1977     Document Type: Article

References (26)

1. Mahley, R. W. (1988) Science 240, 622-628.
2. Ignatius, M. J., Gebicke-Harter, P. J., Skene, J. H. P., Schilling, J. W., Weisgraber, K. H., Mahley, R. W. & Shooter, E. M. (1986) Proc. Natl. Acad. Sci. USA 83, 1125-1129.
3. Boyles, J., Pitas, R. E., Wilson, E., Mahley, R. W. & Taylor, J. M. (1985) J. Clin. Invest. 76, 1501-1513.
4. Pitas, R. E., Boyles, J. K., Lee, S. H., Foss, D. & Mahley, R. W. (1987) Biochim. Biophys. Acta 917, 148-161.
5. Elshourbagy, N. A., Liao, W. S., Mahley, R. W. & Taylor, J. M. (1985) Proc. Natl. Acad. Sci. USA 82, 203-207.
6. Boyles, J. K., Zoellner, C. D., Anderson, L. J., Kosik, L. M., Pitas, R. E., Weisgraber, K. H., Hui, D. Y., Mahley, R. W., Gebicke-Haerter, P. J., Ignatius, M. J. & Shooter, E. M. (1989) J. Clin. Invest. 83, 1015-1031.
7. Snipes, G. J., McGuire, C. B., Norden, J. J. & Freeman, J. A. (1986) Proc. Natl. Acad. Sci. USA 83, 1130-1134.
8. Namba, Y., Tomonaga, M., Kawasaki, H., Otomo, E. & Ikeda, K. (1991) Brain Res. 541, 163-166.
9. Prusiner, S. B., Hsiao, K. K., Bredesen, D. E. & DeArmond, S. J. (1989) in Handbook of Clinical Neurology, ed. McKendall, R. R. (Elsevier, Amsterdam), Vol. 12, pp. 543-580.
10. Diedrich, J. F., Minnigan, H., Carp, R. I., Whitaker, J. N., Race, R., Frey, W., II, & Haase, A. T. (1991) J. Virol. 65, 4759-4768.
11. Selkoe, D. J. (1991) Neuron 6, 487-498.
12. Beyreuther, K. & Masters, C. L. (1991) Brain Pathol. 1, 241-251.
13. Wenham, P. R., Price, W. H. & Blundell, G. (1991) Lancet 337, 1158-1159.
14. Hixson, J. E. & Vernier, D. T. (1990) J. Lipid Res. 31, 545-548.
15. Pericak-Vance, M. A., Bebout, J. L., Gaskell, P. C., Jr., Yamaoka, L. H., Hung, W. Y., Alberts, M. J., Walker, A. P., Bartlett, R. J., Haynes, C. A., Welsh, K. A., Earl, N. L., Heyman, A., Clark, C. M. & Roses, A. D. (1991) Am. J. Hum. Genet. 48, 1034-1050.
16. Dausset, J., Cann, H., Cohen, D., Lathrop, M., Lalouel, J. M. & White, R. (1990) Genomics 6, 575-577.
17. Schellenberg, G. D., Deeb, S. S., Boehnke, M., Bryant, E. M., Martin, G. M., Lampe, T. H. & Bird, T. D. (1987) J. Neurogenet. 4, 97-108.
18. Potter, H., Abraham, C. R. & Dressler, D. (1991) in Alzheimer's Disease: Basic Mechanisms, Diagnosis and Therapeutic Strategies, eds. Iqbal, K., McLachlan, D. R. C., Winblad, B. & Wisniewski, H. M. (Wiley, New York), pp. 275-279.
19. Pitas, R. E., Boyles, J. K., Lee, S. H., Hui, D. & Weisgraber, K. H. (1987) J. Biol. Chem. 262, 14352-14360.
20. Menzel, J., Kladetzky, K. G. & Assmann, G. (1983) Arteriosclerosis 4, 310-315.
21. Wisniewski, T. & Frangione, B. (1992) Neurosci. Lett. 135, 235-238.
22. Roses, A. D., Pericak-Vance, M. A., Saunders, A. M., Schmechel, D., Goldgaber, D. & Strittmatter, W. (1993) Epilepsia, in press.
23. Medori, R., Tritschler, H. J., LeBlanc, A., Villare, F., Manetto, V., Chen, H. Y., Xue, R., Leal, S., Montagna, P., Cortelli, P., Tinuper, P., Avoni, P., Mochi, M., Baruzzi, A., Hauw, J. J., Ott, J., Lugaresi, E., Autilio-Gambetti, L. & Gambetti, P. (1992) N. Engl. J. Med. 326, 444-449.
24. Fink, J. K., Warren, J. T., Jr., Drury, I., Murman, D. & Peacock, M. L. (1991) Neurology 41, 1647-1650.
25. Goldfarb, L. G., Petersen, R. B., Tabaton, M., Brown, P., LeBlanc, A. C., Montagna, P., Cortelli, P., Julien, J., Vital, C., Pendelbury, W. W., Haltia, M., Wills, P. R., Hauw, J. J., McKeever, P. E., Monari, L., Schrank, B., Swergold, G. D., Autilio-Gambetti, L., Gajdusek, D. C., Lugaresi, E. & Gambetti, P. (1992) Science 258, 806-808.
26. Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B. & Selkoe, D. J. (1992) Science 359, 322-325.