Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of α-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 90, Issue 5, 1993, Pages 1711-1715

  Pauwels, Rudi ^a   Andries, Koen ^b   Debyser, Zeger ^a   Van Daele, Paul ^b   Schols, Dominique ^a   Stoffels, Paul ^b   De Vreese, Karen ^a   Woestenborghs, Robert ^b   Vandamme, Anne Mieke ^a   Janssen, Cornelus G M ^b   Anne, Jef ^a   Cauwenbergh, Geert ^b   Desmyter, Jan ^a   Heykants, Jozef ^b   Janssen, Marcel A C ^b   De Clercq, Erik ^a   Janssen, Paul A J ^b  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

ALPHA ANILINOPHENYLACETAMIDE DERIVATIVE; ANTIVIRUS AGENT; IMIDAZO[4,5,1 JK][1,4]BENZODIAZEPINE DERIVATIVE; LOVIRIDE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATION; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRION; VIRUS INHIBITION; VIRUS REPLICATION;

ACETAMIDES; ACETOPHENONES; ANILINE COMPOUNDS; HIV CORE PROTEIN P24; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HIV-2; HUMAN; MALE; REVERSE TRANSCRIPTASE INHIBITORS; SIV; SUPPORT, NON-U.S. GOV'T; VIRUS INHIBITORS; VIRUS REPLICATION;

EID: 0027407551     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.90.5.1711     Document Type: Article

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