Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential actions on firing pattern related to anatomical localization

Journal of Neural Transmission

Volumn 91, Issue 1, 1993, Pages 13-25

  Murase, S ^a   Mathe J M ^a   Grenhoff, J ^a   Svensson, T H ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Burst firing; MK 801; N methyl D aspartate; nucleus parabrachialis pigmentosus; nucleus paranigralis; phencyclidine; substantia nigra; ventral tegmental area

Indexed keywords

CHLORAL HYDRATE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; DOPAMINERGIC NERVE CELL; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MESENCEPHALON; NERVE ENDING; NONHUMAN; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

ACTION POTENTIALS; ANIMAL; APOMORPHINE; DIZOCILPINE MALEATE; DOPAMINE; MALE; NEURONS; PHENCYCLIDINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; STIMULATION, CHEMICAL; SUBSTANTIA NIGRA; SUPPORT, NON-U.S. GOV'T; TEGMENTUM MESENCEPHALI;

EID: 0027406714     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/BF01244915     Document Type: Article

References (50)

1. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study
2. Ultrastructural localization of tyrosine hydroxylase in the rat ventral tegmental area: relationship between immunolabelling density and neuronal associations
3. Ultrastructural localization of neurotensin-like immunoreactivity within dense core vesicles in perikarya, but not terminals, colocalizing tyrosine hydroxylase in the rat ventral tegmental area
4. Extracellular dopamine and neurotensin in rat prefrontal cortex in vivo: effects of medial forebrain bundle stimulation frequency, stimulation pattern, and dopamine autoreceptors
5. Dopamine-containing systems in the CNS
6. Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate
7. Dopamine-containing neurons in the mammalian central nervous system: electrophysiology and pharmacology
8. Central sympathomimetric activity of (+)-5-methyl-10, 11-dihydro-5H-dibenzo[a, d]cyclohepten-5, 10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
9. Electrophysiological identification of mesencephalic ventromedial tegmental (VMT) neurons projecting to the frontal cortex, septum and nucleus accumbens
10. Glutamate receptors in the substantia nigra of Parkinson's disease brains
11. Collateralization of monoamine neurons: mesotelencephalic dopamine projections to caudate, septum, and frontal cortex
12. The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity
13. Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons
14. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry
15. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. I. Identification and characterization
16. The control of firing pattern in nigral dopamine neurons: burst firing
17. Nicotinic effects on the firing pattern of midbrain dopamine neurons
18. The excitatory amino acid antagonist kynurenate induces pacemaker-like firing of dopamine neurons in rat ventral tegmental area in vivo
19. Firing patterns of midbrain dopamine neurons: differences between A9 and A10 cells
20. NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus
21. Recent advances in the phencyclidine model of schizophrenia
22. Cholecystokinin and neurotensin mRNAs are differentially expressed in subnuclei of the ventral tegmental area
23. Neuropharmacology of phencyclidine: basic mechanisms and therapeutic potential
24. Two types of neurone in the rat ventral tegmental area and their synaptic inputs
25. Effect of MK-801 on endogenous dopamine release in vivo
26. Mesocorticolimbic dopaminergic network: functional and regulatory roles
27. Organization of catecholamine neurons projecting to the frontal cortex in the rat
28. The location of neurones with pontamine sky blue
29. Study of a new schizophrenomimetic drug-Sernyl
30. Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices
31. Central catecholamine neuron systems: anatomy and physiology of the dopamine systems
32. Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity
33. Phencyclidine activates rat A10 dopamine neurons but reduces burst activity and causes regularization
34. The cytoarchitecture of the interfascicular nucleus and ventral tegmental area of Tasai in the rat
35. Effects of phencyclidine on the spontaneous activity of monoaminergic neurons
36. Interactions of phencyclidine receptors agonist MK-801 with dopaminergic system: regional studies in the rat
37. The effects of the phencyclidine analogs BCTP and TCP on nigrostriatal dopamine neuronal activity
38. Evidence for the presence of N-methyl-D-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study
39. Efferents and afferents of the ventral tegmental-A10 region studied after local injection of [3H]leucine and horseradish peroxidase
40. Electrophysiological effects of selective a-receptor agonists, antagonists, and the selective phencyclidine receptor agonist MK-801 on midbrain dopamine neurons
41. A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive NMDA antagonist D-CPPene with regard to dopamine turnover and locomotor-stimulatory properties in mice
42. The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat
43. The behavioural effects of MK-801: a comparison with antagonists acting non-competetively and competetively at the NMDA receptor
44. Dopaminergic neurons in the rat ventral tegmental area. I. Identification and characterization
45. The variability of central neural activity in a sensory system, and its implications for the central reflection of sensory events
46. The behavioral pharmacology of NMDA receptor antagonists
47. Sites for antagonism on the N-methyl-D-aspartate receptor channel complex
48. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist