Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists

European Journal of Pharmacology: Molecular Pharmacology

Volumn 245, Issue 2, 1993, Pages 179-182

  Kuoppamäki, Mikko ^a   Syvälahti, Erkka ^a   Hietala, Jarmo ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

5 HT1C receptors; Choroid plexus; Clozapine; Clozapine N oxide; N Desmethylclozapine

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CLOZAPINE; CLOZAPINE N OXIDE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DRUG METABOLITE; INOSITOL PHOSPHATE; KETANSERIN; MESULERGINE; METHYSERGIDE; NORCLOZAPINE; PARGYLINE; RADIOLIGAND; SEROTONIN 1C RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN ANTAGONIST; SPIPERONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHOROID PLEXUS; CONTROLLED STUDY; DRUG CONCENTRATION; HYDROLYSIS; LIGAND BINDING; MALE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RAT;

ANIMAL; CHOROID PLEXUS; CLOZAPINE; IN VITRO; MALE; METHYSERGIDE; PHOSPHATIDYLINOSITOLS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SEROTONIN ANTAGONISTS; SUPPORT, NON-U.S. GOV'T;

EID: 0027405998     PISSN: 09224106     EISSN: None     Source Type: Journal    
DOI: 10.1016/0922-4106(93)90126-T     Document Type: Article

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