Detection of point mutations in the p53 gene: Comparison of single‐strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques

Human Mutation

Volumn 2, Issue 1, 1993, Pages 58-66

  Condie, Alison ^a   Eeles, Rosalind ^b,c   Borresen, Anne‐Lise ^d   Coles, Christopher ^a   Cooper, Colin ^b   Prosser, Jane ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c ROYAL MARSDEN HOSPITAL   (United Kingdom)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

CDGE; Chemical mismatch; HOT; p53; Point mutation; SSCP

Indexed keywords

HYDROXYLAMINE; OSMIUM TETRAOXIDE; PROTEIN P53;

ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; DNA DETERMINATION; DNA POLYMORPHISM; EXAMINATION; GENE; GENE MUTATION; HUMAN; INTERMETHOD COMPARISON; OBSERVATION; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TECHNIQUE;

COMPARATIVE STUDY; DNA, SINGLE-STRANDED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENES, P53; GENETIC TECHNIQUES; HYDROXYLAMINE; HYDROXYLAMINES; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; OSMIUM TETROXIDE; POINT MUTATION; POLYMORPHISM (GENETICS);

EID: 0027404853     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.1380020111     Document Type: Article

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