Open-Angle Glaucoma

New England Journal of Medicine

Volumn 328, Issue 15, 1993, Pages 1097-1106

  Quigley, Harry A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; ADRENALIN; APRACLONIDINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; PILOCARPINE; PROSTAGLANDIN DERIVATIVE;

APLASTIC ANEMIA; BEHAVIOR THERAPY; BRADYCARDIA; BRONCHOSPASM; GONIOSCOPY; HUMAN; LASER SURGERY; LETHARGY; OPEN ANGLE GLAUCOMA; OPTIC DISK; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; TONOMETRY; TRABECULAR MESHWORK; VISUAL FIELD; VISUAL IMPAIRMENT;

GLAUCOMA, OPEN-ANGLE; GONIOSCOPY; HUMAN; RISK FACTORS; TONOMETRY; VISUAL FIELDS;

EID: 0027399771     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199304153281507     Document Type: Review

References (114)

1. Quigley HA, Brown AE, Morrison JD, Drance SM The size and shape of the optic disc in normal human eyes. Arch Ophthalmol 1990; 108:51-57
2. Jonas JB, Gusek GC, Naumann GOH Optic disc, cup and neuroretinal rim size, configuration and correlations in normal eyes. Invest Ophthalmol Vis Sci 1988; 23:1151-1158 [Erratum, Invest Ophthalmol Vis Sci 1991;32:1893, 1992;33:474-5.]
3. Quigley HA, Addicks EM, Green WR Optic nerve damage in human glaucoma. III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy. Arch Ophthalmol 1982; 100:135-146
4. Repka MX, Quigley HA The effect of age on normal human optic nerve fiber number and diameter. Ophthalmology 1989; 96:26-32
5. Balazsi AG, Rootman J, Drance SM, Schulzer M, Douglas GR The effect of age on the nerve fiber population of the human optic nerve. Am J Ophthalmol 1984; 97:760-766
6. Jonas JB, Muller-Bergh JA, Schlotzer-Schrehardt UM, Naumann GOH Histomorphometry of the human optic nerve. Invest Ophthalmol Vis Sci 1990; 31:736-744
7. Mikelberg FS, Drance SM, Schulzer M, Yidegiligne HM, Weis MM The normal human optic nerve: axon count and axon diameter distribution. Ophthalmology 1989; 96:1325-1328
8. Jonas JB, Gusek GC, Naumann GOH Optic disc morphometry in chronic primary open-angle glaucoma. I. Morphometric intrapapillary characteristics. Graefes Arch Clin Exp Ophthalmol 1988; 226:522-530
9. Quigley HA, Hohman RM, Addicks EM, Massof RW, Green WR Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am J Ophthalmol 1983; 95:673-691
10. Gaasterland D, Tanishima T, Kuwabara T Axoplasmic flow during chronic experimental glaucoma. I. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping. Invest Ophthalmol Vis Sci 1978; 17:838-846
11. Quigley HA, Hohman RM, Sanchez RM, Addicks EM Optic nerve head blood flow in chronic experimental glaucoma. Arch Ophthalmol 1985; 103:956-962
12. Heijl A, Drance SM, Douglas GR Automatic perimetry (COMPETER): ability to detect early glaucomatous field defects. Arch Ophthalmol 1980; 98:1560-1563
13. Flammer J, Drance SM, Augustiny L, Funkhouser A Quantification of glaucomatous visual field defects with automated perimetry. Invest Ophthalmol Vis Sci 1985; 26:176-181
14. Quigley HA, Dunkelberger GR, Green WR Chronic human glaucoma causing selectively greater loss of large optic nerve fibers. Ophthalmology 1988; 95:357-363
15. Glovinsky Y, Quigley HA, Dunkelberger GR Retinal ganglion cell loss is size dependent in experimental glaucoma. Invest Ophthalmol Vis Sci 1991; 32:484-491
16. Dandona L, Hendrickson A, Quigley HA Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus. Invest Ophthalmol Vis Sci 1991; 32:1593-1599
17. Radius RL, Anderson DR The course of axons through the retina and optic nerve head. Arch Ophthalmol 1979; 97:1154-1158
18. Enroth-Cugell C, Robson JG Functional characteristics and diversity of cat retinal ganglion cells: basic characteristics and quantitative description. Invest Ophthalmol Vis Sci 1984; 25:250-267
19. Tyler CW Specific deficits of flicker sensitivity in glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci 1981; 20:204-212
20. Silverman SE, Trick GL, Hart WM Jr Motion perception is abnormal in primary open-angle glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci 1990; 31:722-729
21. Glovinsky Y, Quigley HA, Drum B, Bissett RA, Jampel HD A whole-field scotopic retinal sensitivity test for the detection of early glaucoma damage. Arch Ophthalmol 1992; 110:486-490
22. Levin PS, Newman SA, Quigley HA, Miller NR A clinicopathologic study of optic neuropathies associated with intracranial mass lesions with quantification of remaining axons. Am J Ophthalmol 1983; 95:295-306
23. Sadun AA, Bassi CJ Optic nerve damage in Alzheimer's disease. Ophthalmology 1990; 97:9-17
24. National Center for Health Statistics, Ganley JP, Roberts J. Eye conditions and related need for medical care among persons 1-74 years of age: United States, 1971-72. Vital and health statistics. Series 11. No. 228. Washington, D.C.: Government Printing Office, 1983. (DHHS publication no. (PHS) 83-1678.)
25. Leibowitz HM, Krueger DE, Maunder LR, The Framingham Eye Study monograph: an ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. Surv Ophthalmol 1980; 24: Suppl: 335-610
26. Sommer A, Tielsch JM, Katz J, Racial differences in the cause-specific prevalence of blindness in East Baltimore. N Engl J Med 1991; 325:1412-1417
27. Tielsch JM, Sommer A, Katz J, Royall RM, Quigley HA, Javitt J Racial variations in the prevalence of primary open-angle glaucoma: the Baltimore Eye Survey. JAMA 1991; 266:369-374
28. Armaly MF Ocular pressure and visual fields: a ten-year follow-up study. Arch Ophthalmol 1969; 81:25-40
29. Graham PA The definition of pre-glaucoma: a prospective study. Trans Ophthalmol Soc U K 1969; 88:153-165
30. Perkins ES The Bedford glaucoma survey. I. Long-term follow-up of borderline cases. Br J Ophthalmol 1973; 57:179-185
31. Sommer A, Katz J, Quigley HA, Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Arch Ophthalmol 1991; 109:77-83
32. Armaly MF, Krueger DE, Maunder L, Biostatistical analysis of the collaborative glaucoma study. I. Summary report of the risk factors for glaucomatous visual-field defects. Arch Ophthalmol 1980; 98:2163-2171
33. Sommer A Intraocular pressure and glaucoma. Am J Ophthalmol 1989; 107:186-188
34. Hart WM Jr, Yablonski M, Kass MA, Becker B Multivariate analysis of the risk of glaucomatous visual field loss. Arch Ophthalmol 1979; 97:1455-1458
35. Drance SM, Schulzer M, Thomas B, Douglas GR Multivariate analysis in glaucoma: use of discriminant analysis in predicting glaucomatous visual field damage. Arch Ophthalmol 1981; 99:1019-1022
36. Fazio P, Krupin T, Feitl ME, Werner EB, Carre DA Optic disc topography in patients with low-tension and primary open angle glaucoma. Arch Ophthalmol 1990; 108:705-708
37. Miller KM, Quigley HA Comparison of optic disc features in low-tension and typical open-angle glaucoma. Ophthalmic Surg 1987; 18:882-889
38. King D, Drance SM, Douglas G, Schulzer M, Wijsman K Comparison of visual field defects in normal-tension glaucoma and high-tension glaucoma. Am J Ophthalmol 1986; 101:204-207
39. Caprioli J, Spaeth GL Comparison of the optic nerve head in high- and low-tension glaucoma. Arch Ophthalmol 1985; 103:1145-1149
40. Caprioli J, Spaeth GL Comparison of visual field defects in the low-tension glaucomas with those in the high-tension glaucomas. Am J Ophthalmol 1984; 97:730-737
41. Hollows FC, Graham PA Intra-ocular pressure, glaucoma, and glaucoma suspects in a defined population. Br J Ophthalmol 1966; 50:570-586
42. Bengtsson B The prevalence of glaucoma. Br J Ophthalmol 1981; 65:46-49
43. Mason RP, Kosoko O, Wilson MR, National survey of the prevalence and risk factors of glaucoma in St. Lucia, West Indies. Part I: Prevalence findings. Ophthalmology 1989; 96:1363-1368
44. Tielsch JM, Sommer A, Katz J, Quigley HA, Ezrine S Socioeconomic status and visual impairment among urban Americans. Arch Ophthalmol 1991; 109:637-641
45. Javitt JC, McBean AM, Nicholson GA, Babish JD, Warren JL, Krakauer H Undertreatment of glaucoma among black Americans. N Engl J Med 1991; 325:1418-1422
46. Becker B, Kolker AE, Roth FD Glaucoma family study. Am J Ophthalmol 1960; 50:557-567
47. Leske MC, Podgor MJ Intraocular pressure, cardiovascular risk variables, and visual field defects. Am J Epidemiol 1983; 118:280-287
48. Morgan RW, Drance SM Chronic open-angle glaucoma and ocular hypertension: an epidemiological study. Br J Ophthalmol 1975; 59:211-215
49. Katz J, Sommer A Risk factors for primary open angle glaucoma. Am J Prev Med 1988; 4:110-114
50. Wilson MR, Hertzmark E, Walker AM, Childs-Shaw K, Epstein DL A case-control study of risk factors in open angle glaucoma. Arch Ophthalmol 1987; 105:1066-1071
51. Armaly MF On the distribution of applanation pressure. I. Statistical features and the effect of age, sex, and family history of glaucoma. Arch Ophthalmol 1965; 73:11-18
52. Shiose Y The aging effect on intraocular pressure in an apparently normal population. Arch Ophthalmol 1984; 102:883-887
53. McLeod SM, West SK, Quigley HA, Fozard JL A longitudinal study of the relationship between intraocular and blood pressures. Invest Ophthalmol Vis Sci 1990; 31:2361-2366
54. Tielsch JM The epidemiology of primary open-angle glaucoma. Ophthalmol Clin North Am 1991; 4:649-657
55. Schulzer M, Drance SM, Carter CJ, Brooks DE, Douglas GR, Lau W Biostatistical evidence for two distinct chronic open angle glaucoma populations. Br J Ophthalmol 1990; 74:196-200
56. Daubs JG, Crick RP Effect of refractive error on the risk of ocular hypertension and open angle glaucoma. Trans Ophthalmol Soc U K 1981; 101:121-126
57. Drance SM, Fairclough M, Butler DM, Kottler MS The importance of disc hemorrhage in the prognosis of chronic open angle glaucoma. Arch Ophthalmol 1977; 95:226-228
58. Diehl DLC, Quigley HA, Miller NR, Sommer A, Burney EN Prevalence and significance of optic disc hemorrhage in a longitudinal study of glaucoma. Arch Ophthalmol 1990; 108:545-550
59. Sommer A, Katz J, Quigley HA, Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Arch Ophthalmol 1991; 109:77-83
60. Quigley HA, Addicks EM, Green WR, Maumenee AE Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol 1981; 99:635-649
61. Aguayo AJ, Vidal-Sanz M, Villegas-Perez MP, Keirstead SA, Rasminsky M, Bray GM. Axonal regrowth and connectivity from neurons in the adult rat retina. In: Agardh E, Ehinger B, eds. Retinal signal systems, degenerations, and transplants. Amsterdam: Elsevier, 1986:257-70.
62. Morrison JC, Dorman-Pease ME, Dunkelberger GR, Quigley HA Optic nerve head extracellular matrix in primary optic atrophy and experimental glaucoma. Arch Ophthalmol 1990; 108:1020-1024
63. Tengroth B, Rehnberg M, Amitzboll T A comparative analysis of the collagen type and distribution in the trabecular meshwork, sclera, lamina cribrosa and the optic nerve in the human eye. Acta Ophthalmol Suppl (Copenh) 1985; 173:91-93
64. Hernandez MR, Luo XX, Igoe F, Neufeld AH Extracellular matrix of the human lamina cribrosa. Am J Ophthalmol 1987; 104:567-576
65. Quigley HA, Addicks EM Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage. Arch Ophthalmol 1981; 99:137-143
66. Dandona L, Quigley HA, Brown AE, Enger C Quantitative regional structure of the normal human lamina cribrosa: a racial comparison. Arch Ophthalmol 1990; 108:393-398
67. Hernandez MR, Andrzejewska WM, Neufeld AH Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma. Am J Ophthalmol 1990; 109:180-188
68. Quigley HA, Brown AE, Dorman-Pease ME Alterations in elastin of the optic nerve head in human and experimental glaucoma. Br J Ophthalmol 1991; 75:552-557
69. Quigley HA, Hohman RM, Addicks EM, Green WR Blood vessels of the glaucomatous optic disk in experimental primate and human eyes. Invest Ophthalmol Vis Sci 1984; 25:918-931
70. Quigley HA, Hohman RM, Sanchez RM, Addicks EM Optic nerve head blood flow in chronic experimental glaucoma. Arch Ophthalmol 1985; 103:956-962
71. Sperber GO, Bill A Blood flow and glucose consumption in the optic nerve, retina and brain: effects of high intraocular pressure. Exp Eye Res 1985; 41:639-653
72. Weinstein JM, Duckrow RB, Beard D, Brennan RW Regional optic nerve blood flow and its autoregulation. Invest Ophthalmol Vis Sci 1983; 24:1559-1565
73. Grunwald JE, Riva CE, Stone RA, Keates EU, Petrig BL Retinal autoregulation in open-angle glaucoma. Ophthalmology 1984; 91:1690-1694
74. Alvarado J, Murphy C, Polansky J, Juster R Age-related changes in trabecular meshwork cellularity. Invest Ophthalmol Vis Sci 1981; 21:714-727
75. Lutjen-Drecoll E, Shimizu T, Rohrbach M, Rohen JW Quantitative analysis of ‘plaque material’ in the inner- and outer wall of Schlemm's canal in normal- and glaucomatous eyes. Exp Eye Res 1986; 42:443-455
76. Rohen JW Why is intraocular pressure elevated in chronic simple glaucoma? Anatomical considerations. Ophthalmology 1983; 90:758-765
77. Acott TS, Kingsley PD, Samples JR, Van Buskirk EM Human trabecular meshwork organ culture: morphology and glycosaminoglycan synthesis. Invest Ophthalmol Vis Sci 1988; 29:90-100
78. Johnson DH, Tschumper RC Human trabecular meshwork organ culture: a new method. Invest Ophthalmol Vis Sci 1987; 28:945-953
79. Polansky J, Palmberg P, Matulich D, Cellular sensitivity to glucocorticoids in patients with POAG: steroid receptors and responses in cultured skin fibroblasts. Invest Ophthalmol Vis Sci 1985; 26:805-809
80. Weinstein BI, Munnangi P, Gordon GG, Southern AL Defects in cortisol-metabolizing enzymes in primary open-angle glaucoma. Invest Ophthalmol Vis Sci 1985; 26:890-893
81. Tielsch JM, Katz J, Singh K, A population-based evaluation of glaucoma screening: the Baltimore Eye Survey. Am J Epidemiol 1991; 134:1102-1110
82. Takamoto T, Schwartz B Photogrammetric measurement of nerve fiber layer thickness. Ophthalmology 1989; 96:1315-1319
83. Mikelberg FS, Airaksinen PJ, Douglas GR, Schulzer M, Wijsman K The correlation between optic disk topography measured by the video-ophthalmograph (Rodenstock analyzer) and clinical measurement. Am J Ophthalmol 1985; 100:417-419
84. Dreher AW, Tso PC, Weinreb RN Reproducibility of topographic measurements of the normal and glaucomatous optic nerve head with the laser tomographic scanner. Am J Ophthalmol 1991; 111:221-229
85. Varma R, Spaeth GL, Steinmann WC, Katz LJ Agreement between clinicians and an image analyzer in estimating cup-to-disc ratios. Arch Ophthalmol 1989; 107:526-529
86. Caprioli J, Ortiz-Colberg R, Miller JM, Tressler C Measurements of peripapillary nerve fiber layer contour in glaucoma. Am J Ophthalmol 1989; 108:404-413
87. Heijl A, Lindgren G, Olsson J, Asman P Visual field interpretation with empiric probability maps. Arch Ophthalmol 1989; 107:204-208
88. Katz J, Sommer A, Gaasterland DE, Anderson DR Comparison of analytic algorithms for detecting glaucomatous visual field loss. Arch Ophthalmol 1991; 109:1684-1689
89. Epstein DL, Krug JH Jr, Hertzmark E, Remis LL, Edelstein DJ A long-term clinical trial of timolol therapy versus no treatment in the management of glaucoma suspects. Ophthalmology 1989; 96:1460-1467
90. Kass MA, Gordon MO, Hoff MR, Topical timolol administration reduced the incidence of glaucomatous damage in ocular hypertensive individuals: a randomized, double-masked, long-term clinical trial. Arch Ophthalmol 1989; 107:1590-1598
91. Schulzer M, Drance SM, Douglas GR A comparison of treated and untreated glaucoma suspects. Ophthalmology 1991; 98:301-307
92. Werner EB, Drance SM, Schulzer M Trabeculectomy and the progression of glaucomatous visual field loss. Arch Ophthalmol 1977; 95:1374-1377
93. Zeimer RC, Wilensky JT, Gieser DK, Viana MAG Association between intraocular pressure peaks and progression of visual field loss. Ophthalmology 1991; 98:64-69
94. Cinotti A, Cinotti D, Grant W, Levobunolol vs timolol for open-angle glaucoma and ocular hypertension. Am J Ophthalmol 1985; 99:11-17
95. Allen RC, Hertzmark E, Walker AM, Epstein DL A double-masked comparison of C. xolol vs timolol in the treatment of open-angle glaucoma. Am J Ophthalmol 1986; 101:535-541
96. McMahon CD, Shaffer RN, Hoskins HD Jr, Hetherington J Jr Adverse effects experienced by patients taking timolol. Am J Ophthalmol 1979; 88:736-738
97. Coleman AL, Diehl DLC, Jampel HD, Bachorik PS, Quigley HA Topical timolol decreases plasma high-density lipoprotein cholesterol level. Arch Ophthalmol 1990; 108:1260-1263
98. Johnson DH, Epstein DL, Allen RC, A one-year multicenter clinical trial of pilocarpine gel. Am J Ophthalmol 1984; 97:723-729
99. Kass MA, Meltzer DW, Gordon M, Cooper D, Goldberg J Compliance with topical pilocarpine treatment. Am J Ophthalmol 1986; 101:515-523
100. Robin AL, Pollack IP, House B, Enger C Effects of ALO 2145 on intraocular pressure following argon laser trabeculoplasty. Arch Ophthalmol 1987; 105:646-650
101. Kass MA Topical carbonic anhydrase inhibitors. Am J Ophthalmol 1989; 107:280-282
102. The Glaucoma Laser Trial Research Group. The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. Ophthalmology 1990; 97:1403-1413
103. Bylsma SS, Samples JR, Acott TS, Van Buskirk EM Trabecular cell division after argon laser trabeculoplasty. Arch Ophthalmol 1988; 106:544-547
104. Hoskins HD Jr, Migliazzo C Management of failing filtering blebs with the argon laser. Ophthalmic Surg 1984; 15:731-733
105. Wilson RP. Technical advances in filtration surgery. In: McAllister JA, Wilson RP, eds. Glaucoma. London: Butterworths, 1986:229-54.
106. The Fluorouracil Filtering Surgery Study Group. Fluorouracil Filtering Surgery Study one-year follow-up. Am J Ophthalmol 1989; 108:625-635
107. Skuta GL, Beeson CC, Higginbotham EJ, Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. Ophthalmology 1992; 99:438-444
108. Molteno ACB, Van Rooyen MMB, Bartholomew RS Implants for draining neovascular glaucoma. Br J Ophthalmol 1977; 61:120-125
109. Schocket SS, Nirankari VS, Lakhanpal V, Richards RD, Lerner BC Anterior chamber tube shunt to an encircling band in the treatment of neovascular glaucoma and other refractory glaucomas: a long-term study. Ophthalmology 1985; 92:553-562
110. Beckman H, Kinoshita A, Rota AN, Sugar HS Transscleral ruby laser irradiation of the ciliary body in the treatment of intractable glaucoma. Trans Am Acad Ophthalmol Otolaryngol 1972; 76:423-436
111. Schwartz LW, Moster MR Neodymium:YAG laser transscleral cyclodiathermy. Ophthalmic Laser Ther 1986; 1:135-141
112. Patel A, Thompson JT, Michels RG, Quigley HA Endolaser treatment of the ciliary body for uncontrolled glaucoma. Ophthalmology 1986; 93:825-830
113. Passo MS, Goldberg L, Elliot DL, Van Buskirk EM Exercise conditioning and intraocular pressure. Am J Ophthalmol 1987; 103:754-757
114. Katz LJ, Spaeth GL, Cantor LB, Poryzees EM, Steinmann WC Reversible optic disc cupping and visual field improvement in adults with glaucoma. Am J Ophthalmol 1989; 107:485-492