A Novel Stereoselective Route to (S)-(+)-α-(Fluoromethyl)histidine: α-Halomethylation of (2R,4S)-3-Benzoyl-2-(1,1-dimethylethyl)-1-methyl-4-[(N-tritylimidazol-4′-yl)methyl]-1,3-imidazolidin-5-one. Synthesis and 1H NMR Spectroscopy

Journal of Organic Chemistry

Volumn 58, Issue 3, 1993, Pages 709-713

  Grozinger, Karl G ^a   Kriwacki, Richard W ^a,b   Leonard, Scott F ^a   Pitner, T Phil ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FLUOROMETHYLHISTIDINE; AMINO ACID DERIVATIVE;

ARTICLE; ENANTIOMER; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 0027399573     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo00055a027     Document Type: Article

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