Correlation between thermal radiosensitization and heat-induced loss of DNA polymerase β activity in CHO cells

International Journal of Radiation Biology

Volumn 63, Issue 2, 1993, Pages 215-221

  Dikomey, E ^a   Jung, H ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERTHERMIA; PRIORITY JOURNAL; RADIOSENSITIZATION;

ANIMAL; CHO CELLS; COMPARATIVE STUDY; DNA POLYMERASE I; HAMSTERS; HEAT; RADIATION TOLERANCE; SUPPORT, NON-U.S. GOV'T;

EID: 0027398815     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553009314550281     Document Type: Article

References (35)

1. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
2. Enhanced radiation-induced killing of Chinese hamster cells by dideoxythymidine
3. Hyperthermic potentiation of the effects of a clinically significant X-ray dose on cell survival, DNA damage, and DNA repair
4. Effect of cycloheximide on heat-induced cell killing, radiosensitization, and loss of cellular DNA polymerase activities in Chinese hamster ovary cells
5. Recovery of CHO cells from hyperthermic potentiation to X-rays: repair of DNA and chromatin
6. Hyperthermic effects on DNA repair mechanisms
7. Lethal and potentially lethal lesions induced by radiation: a unified repair model
8. Effect of hyperthermia at 42 and 45°C on repair of radiation-induced DNA strand breaks in CHO cells
9. Three classes of DNA strand breaks induced by X-irradiation and internal β-rays
10. Effect of heat on induction and repair of DNA strand breaks in X-irradiated CHO cells
11. Correlation between polymerase β activity and thermal radiosensitization in CHO cells
12. Thermal radiosensitization in CHO cells by prior heating at 41–46°C
13. Effect of thermotolerance and step-down heating on thermal radiosensitization in CHO cells
14. Reduction of DNA-polymerase β activity of CHO cells by single and combined heat treatments
15. Differential heat sensitivity of mammalian DNA polymerases
16. Involvement of DNA polymerases α in Simian virus 40 DNA replication
17. Saturable repair models of radiation action in mammalian cells
18. Inhibition of repair of radiation-induced strand breaks by hyperthermia, and its relationship to cell survival after hyperthermia alone
19. The occurrence of DNA strand breaks after hyperthermic treatments of mammalian cells with and without radiation
20. Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells
21. DNA polymerase activity in heat killing and hyperthermic radiosensitization of mammalian cells as observed after fractionated heat treatments
22. Models and mechanisms of hyperthermia
23. Interaction of hyperthermia and radiation in tolerant and nontolerant HeLa S3 cells: role of DNA polymerase inactivation
24. A generalized formulation of dual radiation action
25. Hyperthermic enhancement of radiation cell killing in HeLa S3 cells and its effect on the production and repair of DNA strand breaks
26. Effects of hyperthermia on repair of radiation-induced DNA strand breaks
27. DNA polymerase α and β activities during the cell cycle and their role in heat radiosensitization in Chinese hamster ovary cells
28. Heat radiosensitization and the level of DNA polymerases α and β in human colony-forming unit-granulocyte-macrophage and myeloid leukemias sensitive and resistant to chemotherapeutic agents
29. Effect of hyperthermia on CHO DNA polymerase α and β
30. An ‘incomplete-repair’ model for survival after fractionated and continuous irradiations
31. Production and excision of 5′, 6′-dihydroxydihydrothymine type products in the DNA of preheated cells
32. Excision of X-ray-induced thymine damage in chromatin from heated cells
33. Alterations in the nuclear matrix protein mass correlate with heat-induced inhibition of DNA single-strand break repair