Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid

European Journal of Pharmacology

Volumn 230, Issue 2, 1993, Pages 215-221

  Hu, Shiling ^a   Kim, Helen S ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Arachidonic acid; Cytochrome P450 epoxygenase; Epoxyeicosatrienoic acid; K+ channel openers; K+ channels (Ca2+ activated); Patch clamp method

Indexed keywords

11,12 EPOXY 5,8,14 ICOSATRIENOIC ACID; 14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; 5,6 EPOXY 8,11,14 ICOSATRIENOIC ACID; 8,9 EPOXYICOSATRIENOIC ACID; CYTOCHROME P450; GLIBENCLAMIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA; ARACHIDONIC ACID METABOLISM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; ELECTROPHYSIOLOGY; GUINEA PIG; NONHUMAN; PATCH CLAMP; PORTAL VEIN; PRIORITY JOURNAL; RABBIT; RAT; SMOOTH MUSCLE FIBER; SWINE; TAIL ARTERY; VASCULAR SMOOTH MUSCLE;

ANIMAL; ARACHIDONIC ACIDS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG SYNERGISM; ELECTROPHYSIOLOGY; GUINEA PIGS; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNELS; RABBITS; RATS; SPECIES SPECIFICITY; SWINE;

EID: 0027389456     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(93)90805-R     Document Type: Article

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