Cytochromes P-450 in human hepatocyte plasma membrane: Recognition by several autoantibodies

Gastroenterology

Volumn 104, Issue 1, 1993, Pages 203-216

  Loeper, Jacqueline ^a,b,c,d,e,f   Descatoire, Veronique ^a,b,c,d,e,f   Maurice, Michele ^a,b,c,d,e,f   Beaune, Philippe ^a,b,c,d,e,f   Belghiti, Jacques ^a,b,c,d,e,f   Houssin, Didier ^a,b,c,d,e,f   Ballet, Francois ^a,b,c,d,e,f   Feldmann, Gerard ^a,b,c,d,e,f   Guengerich, F Peter ^a,b,c,d,e,f   Pessayre, Dominique ^a,b,c,d,e,f  

^a la Recherche Médicale: Unit 24 ^*  (France)

^b Institut National de l a Santé et de la Recherche Médicale   (France)

^c HÔPITAL SAINT ANTOINE   (France)

^d BEAUJON HOSPITAL   (France)

^e Hôpital Saint Antoine ^*  (France)

^f VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CYTOCHROME P450; GLUCOSE 6 PHOSPHATASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNSPECIFIC MONOOXYGENASE;

ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNE HEPATITIS; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOPEROXIDASE STAINING; LIVER CELL MEMBRANE; LIVER MICROSOME; OUTER MEMBRANE; PRIORITY JOURNAL;

AUTOANTIBODIES; CELL MEMBRANE; CYTOCHROME P-450 ENZYME SYSTEM; EPITOPES; FLUORESCENT ANTIBODY TECHNIQUE; HEPATECTOMY; HUMAN; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; KIDNEY; LIVER; MICROSOMES; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXYGENASES; PERFUSION; SUPPORT, NON-U.S. GOV'T;

EID: 0027388999     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0016-5085(93)90853-5     Document Type: Article

References (57)

1. Liver disease associated with anti-liver-kidney microsome antibody in children
2. Chronic active hepatitis associated with anti-liver/kidney microsome antibody type 1: a second type of “autoimmune” hepatitis
3. Antibodies against human cytochrome P-450 db 1 in autoimmune hepatitis type II
4. Anti-liver-kidney microsome antibody recognizes a cytochrome P-450 from IID subfamily
5. A human cytochrome P-450 is recognized by anti-liver/kidney microsome antibodies in autoimmune hepatitis
6. Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is P-450db1
7. Hépatites chroniques: intérêt d'une classification fondée sur la présence ou l'absence de l'antigène HBs, de l'anticorps antimuscle lisse et de l'anticorps anti-reticulum endoplasmique
8. A new anti-liver-kidney microsome antibody (anti-LKM2) in tienilic acid-induced hepatitis
9. Human antimicrosome antibodies appearing in a drug induced hepatitis are directed against a cytochrome P-450 hydroxylating the drug
10. Genetic polymorphism of human cytochrome P-450 (S)-mephenytoin hydroxylase: studies with human autoantibodies suggest a functionally altered cytochrome P-450 isoenzyme as cause of the genetic deficiency
11. Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450 IA2
12. Chronic active hepatitis associated with vitiligo, nail dystrophy, alopecia and a new variant of LKM antibodies
13. Identification of cytochrome P-450 IA2 as a human autoantigen
14. B-type cytochromes in plasma membranes isolated from rat liver, in comparison with those of endomembranes
15. Distribution of enzymes involved in metabolism of polycyclic aromatic hydrocarbons among rat liver endomembranes and plasma membranes
16. Presence of functional cytochrome P-450 on isolated rat hepatocyte plasma membrane
17. Presence of functionally active cytochrome P-450 IIE 1 in the plasma membrane of rat hepatocytes
18. The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: an ultrastructural immunocytochemical characterization
19. An analysis of the components of U.W. solution using the isolated perfused rabbit liver
20. Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots
21. The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature
22. Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism
23. Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae
24. Separation of human liver tolbutamide hydroxylase and (S)-mephenytoin 4′-hydroxylase cytochrome P-450 enzymes
25. Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
26. Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P-450 isoenzyme with high activity for bufuralol hydroxylation
27. Characterization of a human liver cytochrome P-450 involved in the oxidation of debrisoquin and other drugs by using antibodies raised to the analogous rat enzyme
28. Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj
29. Role of human cytochrome P-450 IIE1 in the oxidation of several low molecular weight cancer suspects
30. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation: a prototype for genetic polymorphism in oxidative drug metabolism
31. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
32. Purification and characterization of human liver cytochrome P-450-ALC
33. Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase
34. Characterization of mRNA species related to human liver cytochrome P-450 nifedipine oxidase and the regulation of catalytic activity
35. Isolation, culture and characterization of adult human hepatocytes from surgical liver biopsies
36. Demonstration and partial characterization of glutathione disulfide-stimulated ATPase activity in the plasma membrane fraction from rat hepatocytes
37. Improved method for isolation of plasma membrane on cationic beads: membranes from dictyostelium discoideum
38. Membrane isolation on polylysine-coated beads: plasma membrane from Hela cells
39. Presence of covalently bound metabolites on rat hepatocyte plasma membrane proteins after administration of isaxonine, a drug leading to immunoallergic hepatitis in man
40. Isolation of rat liver plasma membrane fragments in isotonic sucrose
41. Application of a one-step procedure for measuring inorganic phosphate in the presence of proteins: the actomyosin ATPase system
42. Pyridine induction of cytochrome P-450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation
43. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
44. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose: procedure and some applications
45. Color modification of diaminobenzidine (DAB). Precipitation by metallic ions and its application for double immuno-histochemistry
46. Formation of plasma membrane domains in rat hepatocytes and hepatoma cell lines in culture
47. The early stages of absorption of injected horse radish peroxidase in the proximal tubules of mouse kidney. Ultrastructural cytochemistry by a new technique
48. Halothane hepatitis. Detection of a constitutional susceptibility factor
49. Antibodies against the hepatic asialoglycoprotein receptor perfused in situ preferentially attach to periportal liver cells in the rat
50. Induction of aryl hydrocarbon hydroxylase activity in cultured human lymphocytes
51. Fc receptors of liver sinusoidal endothelium in normal rats and humans: a histologic study with soluble immune complexes
52. Isolation of chromaffin cell plasma membranes on polycationic beads
53. An immunochemical approach to investigating the mechanism of halothane-induced hepatotoxicity
54. The intralobular distribution of ethanol-inducible P-450IIE1 in rat and human liver
55. Immunocytochemical evidence for the maintenance of cytochrome P-450 isozymes, NADPH cytochrome c reductase and epoxide hydrolase in pure and mixed primary cultures of adult human hepatocytes
56. Class I and class II major histocompatibility complex antigen expression on hepatocytes: a study in children with liver disease
57. Characterization of anti-liver-kidney microsomal antibody in childhood autoimmune chronic active hepatitis: evidence for IgG subclass restriction, polyclonality and nonreactivity with hepatocyte surface antigens