Tissue inhibitor of metalloproteinases‐2 inhibits bFGF‐induced human microvascular endothelial cell proliferation

Journal of Cellular Physiology

Volumn 157, Issue 2, 1993, Pages 351-358

  Murphy, Anne N ^a,b   Unsworth, Edward J ^a,c   Stetler‐Stevenson, William G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^c NIH ^*

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; COLLAGENASE; GELATINASE; METALLOPROTEINASE; PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENDOTHELIUM CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

CELL ADHESION; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; COLLAGENASES; DNA; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GLYCOPROTEINS; HUMAN; METALLOENDOPEPTIDASES; MICROCIRCULATION; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; RETINAL VESSELS; THYMIDINE; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASES; TISSUE INHIBITOR-OF METALLOPROTEINASE-2; TRITIUM;

EID: 0027383944     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.1041570219     Document Type: Article

References (44)

1. Tumor cell invasion inhibited by TIMP‐2
2. K562 cells produce and respond to human erythroid‐potentiating activity
3. Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases
4. Collagen‐induced activation of the Mr 72,000 type IV collagenase in normal and malignant fibroblastold cells
5. Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases
6. cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinase
7. Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines
8. Cellular activation of the 72 kDa type IV collagenase/TIMP‐2 complex
9. Primary structure and cDNA cloning of human fibroblast collagenase inhibitor
10. Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor
11. Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases
12. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid potentiating activity
13. Angiogenic factors
14. Expression and modulation of specific, high affinity binding sites for erythropoietin on the human erythroleukemia cell line K562
15. Domain structure of human 72‐kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase‐2 (TIMP‐2) binding regions
16. Molecular characterization and expression of the gene encoding human erythroid‐potentiating activity
17. Human 72‐kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP‐2
18. Interaction of 92‐kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase and activation of the proenzyme with stromelysin
19. Tissue inhibitor of metalloproteinases from human bone marrow stromal cell line KM 102 has erythroid‐potentiating activity, suggesting its possibly bifunctional role in the hematopoietic microenvironment
20. Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin is regulated by endogenous inhibitors
21. Preferential inhibition of 72 kDa and 92 kDa gelatinases by TIMP‐2
22. Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin
23. Antisense RNA‐induced reduction in metalloproteinase inhibitor causes mouse 3T3 cells to become tumorigenic
24. Isolation of a cartilage factor that inhibits tumor neovascularization
25. Control of tumor growth in animals by infusion of an angiogenesis inhibitor
26. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
27. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment
28. Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade
29. In vitro angiogenesis on the human amniotic membrane: Requirement for basic fibroblast growth factor‐induced proteinases
30. A metalloproteinase inhibitor as an inhibitor of neovascularization
31. Identification of an inhibitor of neovascularization from cartilage
32. Purification and partial amino acid sequence of a bovine cartilage‐derived collagenase inhibitor
33. Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity
34. Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells
35. Type IV collagenases and TIMPs modulate endothelial cell morphogenesis in vitro
36. Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16‐F10 melanoma cells
37. Tissue inhibitor of metalloproteinase (TIMP‐2): A new member of the metalloproteinase inhibitor family
38. Tissue inhibitor of metalloproteinases‐2 (TIMP‐2) has erythroid‐potentiating activity
39. Induction of angiogenesis in chick yolk‐sacmembrane by polyamines and its inhibition by tissue inhibitors of metalloproteinases (TIMP and TIMP‐2)
40. Tumour invasion: Effects of cell adhesion and motility
41. Tissue inhibitor of metalloproteinases‐2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes
42. Human skin fibroblast collagenase inhibitor: Comparative studies in human connective tissue, serum, and amniotic fluid
43. Human skin fibroblast collagenase: Interaction with collagen and collagenase inhibitor
44. SV40‐transformed human lung fibroblasts secrete a 92‐kDa type‐IV collagenase which is identical to that secreted by normal human macrophages