Specific Targeting and Killing Activities of Anti-P-Glycoprotein Monoclonal Antibody MRK16 Directed against Intrinsically Multidrug-resistant Human Colorectal Carcinoma Cell Lines in the Nude Mouse Model

Cancer Research

Volumn 53, Issue 22, 1993, Pages 5475-5482

  Tsuruo, Takashi ^b   Okochi, Etsuko ^a   Ariyoshi, Keiko ^a   Watabe, Hirotsugu ^a   Amann, Egon ^a   Ono, Kenichi ^a  

^a Hoechst Japan LTD ^*  (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; IMMUNOGLOBULIN F(AB')2 FRAGMENT; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; COLORECTAL CARCINOMA; CYTOTOXICITY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

ANIMAL; ANTIBODIES, MONOCLONAL; CARRIER PROTEINS; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; FEMALE; HALF-LIFE; IMMUNOGLOBULINS, FAB; IMMUNOTHERAPY, ADOPTIVE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; P-GLYCOPROTEIN; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0027380596     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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