An overview of glucocorticoid anti-inflammatory actions

European Journal of Clinical Pharmacology

Volumn 45, Issue 1 Supplement, 1993, Pages

  Schleimer, R P ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

allergy; Anti inflammatory; cytokine; Glucocorticoid; leucocyte; neutrophil; osinophil

Indexed keywords

CYTOKINE; GLUCOCORTICOID;

ALLERGY; CONFERENCE PAPER; DRUG MECHANISM; EOSINOPHIL; HUMAN; INFLAMMATION; LEUKOCYTE; NEUTROPHIL; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, STEROIDAL; ARACHIDONIC ACID; BLOOD VESSELS; CYTOKINES; ENDOTHELIUM, VASCULAR; EPITHELIUM; GLUCOCORTICOIDS; HUMAN; INFLAMMATION; INTERLEUKINS; LEUKOCYTE COUNT; LEUKOCYTES; PLATELET ACTIVATING FACTOR;

EID: 0027377816     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/BF01844196     Document Type: Article

References (36)

1. Molecular genetics of corticosteroid action
2. The steroid and thyroid hormone receptor superfamily
3. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
4. Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction
5. Inhibition of in vitro lymphokine synthesis by glucocorticosteroids
6. Glucocorticoid-induced inhibition of T-cell growth factor production. II. The effect on the in vitro generation of cytolytic T-cells
7. Glucocorticoid effects on the production and actions of immune cytokines
8. Effects of glucocorticoids on inflammatory cells relevant to their therapeutic applications in asthma
9. Inhibition of human leucocyte mitosis by prednisolone in vitro
10. Cyclosporin A and dexamethasone suppress T-cell responses by selectively acting at distinct sites of the triggering process
11. Molecular biology of glucocorticoid hormone action
12. Inhibition of platelet-activating factor (PAF)-induced chemotaxis and PAF binding to human eosinophils and neutrophils by the specific ginkgolide-derived PAF antagonist BN 52021
13. An assessment of the effects of glucocorticoids on degranulation, chemotaxis, binding to vascular endothelial cells and formation of leukotriene B4 by purified human neutrophils
14. Modulation of human polymorphonuclear leucocyte IgG Fc receptors and Fc receptormediated functions by IFN-gamma and glucocorticoids
15. Human endothelial cells prolong eosinophil survival. Regulation by cytokines and glucocorticoids
16. Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colonystimulating factor
17. Glucocorticoids inhibit cytokinemediated eosinophil survival
18. Inhibition of basophil histamine release by anti-inflammatory steroids
19. Inhibition of basophil leukotriene release by anti-inflammatory steroids
20. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells
21. The effects of glucocorticoids on mast cells and basophils
22. Acute topical steroid administration blocks mast cell increase and the late asthmatic response of the canine peripheral airways
23. Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells
24. Role of plasma exudation in asthmatic airways
25. Glucocorticoids for asthma — early contributions
26. Dexamethasone inhibits respiratory glycoconjugate secretion from feline airways in vitro by the induction of lipocortin (lipomodulin) synthesis
27. A comparative study of the effects of an inhaled corticosteroid, budesonide, and a β2-agonist, terbutaline, on airway inflammation in newly diagnoses asthma: a randomized, double-blind, parallel-group controlled trial
28. Do cytokines play a role in leucocyte recruitment and activation in the lungs?
29. Reduction of serum interleukin-1like activity after treatment with dexamethasone
30. Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance
31. Interleukin 1 production by human lung tissue. 11. Inhibition by anti-inflammatory steroids
32. Glucocorticoids suppress the production of interleukin 4 by human lymphocytes
33. Expression of endothelial-leucocyte adhesion molecule-1 in elicited late phase allergic reactions
34. Endothelial leucocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo
35. Glucocorticoids inhibit neurogenic plasma extravasation and prevent viruspotentiated extravasation in the rat trachea
36. Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells