T4 endonuclease VII cleaves DNA containing a cisplatin adduct

Journal of Molecular Biology

Volumn 233, Issue 1, 1993, Pages 77-85

  Murchie, Alastair I H ^a   Lilley, David M J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cancer chemotherapy; Diamminedichloroplatinum (II); DNA junction resolution; DNA repair; DNA structure

Indexed keywords

CISPLATIN; ENDONUCLEASE;

ARTICLE; BACTERIOPHAGE T4; DNA REPAIR; DNA STRUCTURE; DRUG DNA ADDUCT; PRIORITY JOURNAL;

BASE SEQUENCE; CISPLATIN; COMPARATIVE STUDY; DNA; ENDODEOXYRIBONUCLEASES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T;

EID: 0027375958     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1993.1486     Document Type: Article

References (63)

1. Bauer, W., Gonias, S. L., Kam, S. K., Wu, K. & Lippard, S. J. (1978). Binding of the antitumor drug platinum uracil blue to closed and nicked circular duplex DNAs. Biochemistry, 17, 1000-1008.
2. Beaucage, S. L. & Caruthers, Μ. H, (1981). Deoxynucleoside phosphoramidites-a new class of key intermediates for deoxypolynucleotide synthesis. Tetrahedron Leiters, 22, 1859-1862.
3. +. Biaphys. Chem. 35, 179-188.
4. Bhattacharvya, A., Murchie, A. I. H., von Kitzing, E., Diekmann, S., Kemper, B. & Lilley, D. M. J. (1991). A model for the interaction of DNA junctions and resolving enzymes. J. Mol. Biol. 221, 1191-1207.
5. Bianehi, Μ. E., Beltrame, M. & Paonessa, G. (1989). Specific recognition of cruciform DNA by nuclear protein HMG1. Science, 243, 1056-1059.
6. Bianehi, Μ. E., Falciola, L., Ferrari, S. & Lilley, D. M. J. (1992). HMG1 protein contains a DNA binding site composed of two similar segments, which have counterparts in other eukaryotic regulatory proteins. EMBOJ. 11, 1055-1063.
7. Bruhn, S. L., Pil, P. M., Essigmann, J. M., Housman, D. E. & Lippard, S. J. (1992). Isolation and characterization of human cDXA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent eisplatin. Proc. Nat. Acad. Sei., U.S.A. 89. 2307-2311.
8. Chen, J.H., Churchill, Μ. E. A., Tullius, T. D., Kallenbach, N. R. & Seeman, N. C. (1988). Construction and analysis of monomobile DNA junctions. Biochemistry, 27, 0032-6038.
9. Churchill, Μ. E., Tullius, T. D., Kallenbach, N. R, & Seeman, N. C. (1988). A Holliday recombination intermediate is twofold symmetric. Proc. Nat. Acad. Sei., V.S.A. 85, 4053-4656.
10. Clegg, R. M., Murchie, A. L H., Zeehel, A., Carlberg, C., Diekmann, S. & Lilley, D. M. J. (1992). Fluorescence resonance energy transfer analysis of the structure of the four-wav DNA junction. Biochemistry, 31, 4846-4856.
11. Cohen, G. L., Bauer, W. R., Barton, J. K, & Lippard, S. J. (1979). Binding of cis- and irans-diammine-dichloroplatinum (IT) to DNA: evidence for shortening and unwinding of the double helix. Science, 203, 1014-1016.
12. Connolly, B., Parsons, C. A., Benson, F. E., Dunderdale, H. J., Sharpies, G. J., Lloyd, R. G. & West, S. C. (1991). Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product. Proc. Nat. Acad. Sei., U.S.A. 88, 6063-6067.
13. Cooper, J. P. & Hagerman, P. J. (1987). Gel electrophoretic analysis of the geometry of a DNA four-wav junction. J. Mol. Biol. 198, 711-719.
14. Cooper, J. P. & Hagerman, P, J. (1989). Geometry of a branched DNA structure in solution. Proc. Nat. Acad. Sei., U.S.A. 86, 7330-7340.
15. Corda, Y., Anin, M. F., Leng, M. & Job, D. (1992). RNA polymerase reacts differently at d(ApG) and d(GpG) adducts in DNA modified by cis-d i amminedieh 1 oro-platinum (II). Biochemistry, 31, 1904-1908.
16. de Massey, B., Studier, F. W., Dorgai, L., Appelbaum, F. & Weisberg, R. A. (1984), Enzymes and the sites of genetic recombination: studies with gene-3 endonuclease of phage T7 and with site-affinity mutants of phage λ. Cold Spring Harbor Symp. Quant. Biol. 49, 715-726.
17. den Hartog, J. H. J., Altona, C., van Boom, J. H., van der Marel, G. A., Haasnoot, C. A. G. & Reedijk, J. (1984). cis-Diamminedichloroplatinum (II) induced distortion in a double helical DNA fragment. J. Anter. Chem. Soc. 106, 1528-1530.
18. Dijt, F. J., Canters, G. W., den Hartog, J. H. J., Maccelius, A. T. M. & Reedijk, J. (1984). Reaction products of ciVdiaminineplatinum compounds with 5'-guanosine monophosphate characterized by high frequency proton NMR. J. Amer. Chem. Soc. 106, 3644-3647.
19. Duckett, D. R., Murchie, A. I. H., Diekmann, S., von Kitzing, F., Kemper, B. & Lilley, D. M. J. (1988). The structure of the Holliday junction and its resolution. Cell, 55, 79-89.
20. Duckett, D. R., Murchie, A. I. H. & Lilley, D. M. J. (1990). The role of metal ions in the conformation of the four-way junction. EMBOJ. 9, 583-590.
21. Duckett, D. R., Murchie, A. T. H., Bhattacharyya, A., Clegg, R. M., Diekmann, S., von Kitzing, E. & Lilley, D. M. J, (1992). The structure of DNA junctions, and their interactions with enzymes. Eur. J. Biochem. 207, 285-295.
22. Eastman, A, (1982). Separation and characterisation of products resulting from the reaction of cis-diammine-dichloroplatinum (II) with deoxyribonucleosides. Biochemistry, 21, 6732-6736.
23. Eastman, A. (1983). Characterization of the adducts produced in DNA by (uVdiamminedichloroplatinum (IT) and cis-dichloro(ethylenediamine)-platinum (IT). Biochemistry, 22, 3927-3933.
24. Elborough, K. & West, S (1988). Specific binding of cruciform DNA structures by a protein from human extracts. Nucl. Acids lies. 16, 3603-3614.
25. Evans, D. H. & Kolodner, R. (1988). Effect of DNA structure and nucleotide sequence on Holliday junction resolution by a Saccharomyces cerevisiae endonuclease. J. Mol. Biol. 201, 69-80.
26. Fichtinger-Schepman, A. M. J., van der Veer, J. L., den Hartog, J. H. H., Lohman, P. H. M. & Reedijk, J. (1985). Adducts of the antitumor drug cis-diammine-dichloroplatinum (II) with DNA: formation, identification and quantitation. Biochemistry, 24, 707-713.
27. Fichtinger-Schepman, A. M. J., van Oosterom, A. T., Lohman, P. H. M. & Berends, F. (1987). cis-diamminedichloroplatinum (Il)-induced DNA adducts in peripheral leukocytes from seven cancer patients. Cancer Res. 47, 3000-3004.
28. Gough, G. W. & Lilley, D. M. J. (1985). DNA bending induced by cruciform formation. Nature (London), 313, 154-156.
29. Harder, H. C. & Rosenberg, B. (1970). Inhibitory effects of antitumor platinum compounds on DNA, RNA, and protein synthesis in mammalian cells in vitro. Int. J. Cancer, 6, 207-216.
30. Jensch, F. & Kemper, B. (1986). Endonuclease VII resolves Y-junctions in branched DNA in vitro. EMBOJ. 5, 181-189.
31. Jeyaseelan, R. & Shanmugam, G, (1988). Human placental endonuclease cleaves Holliday junctions. Biochem. Biophys. Res. Commun. 156, 1054-1060.
32. Kemper, B. & Garabett, M. (1981). Studies on T4 head maturation. 1, Purification and characterisation of gene-49-controlled endonuclease. Eur. J. Biochem. 115, 123-131.
33. Kemper, B. & Janz, E. (1976). Function of gene 49 of bacteriophage T4. 1. Isolation and biochemical characterisation of very fast sedimenting DNA. J. Virol. 18, 992-999.
34. Kimball, A., Guo, Q., Lu, M., Cunningham, R. P., Kalenbach, N. R., Seeman, N. C. & Tullius, T. D. (1990). Construction and analysis of parallel and antiparallel Holliday junctions. J. Biol. Chem. 265, 6544-6547.
35. Kleff, S. & Kemper, B. (1988). Initiation of heteroduplex-loop repair by T4-encoded endonuclease VII in vitro. EMBOJ. 7, 1527-1535.
36. Lepre, C. A. & Lippard, S. J. (1990). Interaction of platinum antitumor compounds with DNA. In Nucleic Acids and Molecular Biology (Eckstein, F. & Lilley, D. M. J., eds), vol. 4, pp. 9-38, Springer-Verlag. Berlin, Heidelberg.
37. Lilley, D. M. J, (1992). HMG has DNA wrapped up. Nature (London), 357, 282-283.
38. Lilley, D. M. G. & Kemper, B. (1984), Cruciform-resolvase interactions in supercoiled DNA. Cell, 36, 413-422.
39. Macquet, J. P. & Butour, J. L. (1978). Modifications of DNA secondary structure upon platinum binding: a proposed model. Biochimie, 60, 601-614.
40. Marrot, L. & Leng, M. (1989). Chemical probes of the conformation of DNA modified cis-diammine-dichloroplatinum (II). Biochemistry, 28, 1454-1461.
41. Marzilli, L. G., Reily, M. D., Heyl, B. L., McMurray, C. T. & Wilson, YV. D. (1984). Evidence for similar structural changes on binding of platinum antitumor agents to DNA and nucleosomes. FEBS Letters, 176, 389-392.
42. Maxam, A. M. & Gilbert, W. (1980). Sequencing end-labelled DNA with base-specific chemical cleavages. Methods Enzymol. 65, 499-560.
43. Millar, D. P., Ho, K. M. & Aroney, M. J. (1988). Modification of DNA dynamics by platinum drug binding: a time-dependent fluorescence depolarization study of the interaction of cis- and Irans-diamminedichloroplatinum (II) with DNA. Biochemistry, 27, 8599-9606.
44. Mizuuchi, K., Kemper, B., Hays, J. & Weisberg, R. A. (1982). T4 endonuclease VII cleaves Holliday structures. Cell, 29, 357-365.
45. Murchie, A. I. H., Clegg, R. M., von Kitzing, E., Duckett, D. R., Diekmann, S. & Lilley, D. M. J. (1989). Fluorescence energy transfer shows that the four-way DNA junction is a right-handed cross of antiparallel molecules. Nature (London), 341, 763-766.
46. Murchie, A. I. H., Carter, W. A., Portugal, J. & Lilley, D. M. J, (1990). The tertiary structure of the fourway DNA junction affords protection against DNasel cleavage. Nucl. Acids Res. 18, 2599-2606.
47. Murchie, A. I. H., Portugal, J. & Lilley, D. M. J. (1991). Cleavage of a four-way DNA junction by a restriction enzyme spanning the point of strand exchange. EMBOJ. 10, 713-718.
48. Parsons, C. A., Tsaneva, I., Lloyd, R. G. & West, S. C. (1992), Interaction of Escherichia coli RuvA and RuvB proteins with synthetic Holliday junctions. Proc. Nat. Acad. Sei., Ü.S.A. 89, 5452-5456.
49. Pil, P. M. & Lippard, S. J. (1992). Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science, 256, 234-237.
50. Pinto, A. L., Naser, L. J., Essigmann, J. M. & Lippard, S. J. (1986). Site-specifically platinated DNA, a new' probe of the biological activity of platinum anticancer drugs. J. Amer. Chem. Soc. 108, 7405-7407.
51. Reed, E., Ozols, R. F., Tarone, R., Yuspa, S. H, & Poirier, M. C. (1987). Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy. Proc. Nat. Acad. Sei., U.S.A. 84, 5024-5028.
52. 2 forms an N7, N7 bis adduct. J. Amer. Chem. Soc. 107, 4916-4924.
53. Rice, J. A., Crothers, D. E., Pinto, A. L. & Lippard, S. J. (1988). The major adduct of the antitumor drug ci, s-diarmninedichloroplatinum (IT) with DNA bends the duplex by ~40° towards the major groove. Proc. Nat. Acad. Sei., U.S.A. 85, 4158-4161.
54. Rosenberg, B., van Camp, L., Trosko, J. E. & Mansour, V. H. (1969). Platinum complexes: a new class of potent antitumor agents. Nature (London), 222, 385-386.
55. Schwartz, A., Sip, M. & Leng, M. (1990). Sodium cyanide: a chemical probe of the conformation of DNA modified by the antitumor drug cis-diammine-dichloroplatinum (II)., J. Amer. Chem. Soc. 112, 3673-3674.
56. Scovell, W. M. & Capponi, V. D. (1982). cijs-Diarmnine-dichloroplatinum (TT) modified DNA stimulates far greater levels of SI nuclease sensitive regions than does the modification produced by the trans isomer. Biochem. Biophys. Res. Commun. 107, 1138-1143.
57. 2-(d(GpG))], the principle adduct formed by os-diamminedichloroplatinum (TI) with DNA. J. Amer. Chem. Soc. 110, 7368-7381.
58. Sinha, N. D., Biernat, d., McManus, d. & Koster, H. (1984). Polymer support oligonucleotide synthesis XVIII: use of j3-cyanoethyl-N, N-dialkylamino/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product. Nucl. Acids Res. 12, 4539-1557.
59. Tomaschewski, D. (1988). Endonuklease VII des bakteriophagen T4: Sequenzierung und Überexpression. Ph.D. thesis, Universität Bochum, ERG.
60. Visse, R., de Ruijter, M., Brower, d., Brandsma, J. A. & van de Putte, P. (1991). Uvr excision repair protein complex of Escherichia coli binds to the convex side of a cisplatin-induced kink in the DNA. J. Biol. Chem. 266, 7609-7617.
61. von Kitzing, E., Lilley, D. M. d. & Diekmann, S. (1990). The stereochemistry of a four-way DNA junction: a theoretical study. Nucl. Acids Res. 18, 2671-2683.
62. Waldman, A. S. & Liskay, R. M. (1988). Resolution of synthetic Holliday structures by an extract of human cells. Nucl. Acids Res. 16, 10244-10266.
63. West, S. C., Parsons, C. A. & Picksley, S. M. (1987). Purification and properties of a nuclease from Saccharomyces cerevisiae that cleaves DNA at cruciform junctions. J. Biol. Chem. 262, 12752-12758.