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Current Opinion in Immunology
Volumn 5, Issue 6, 1993, Pages 968-973
Modern concepts of immunotherapy
Author keywords

[No Author keywords available]
Indexed keywords

ALLERGEN; CD4 ANTIGEN; CYTOKINE; EPITOPE; HLA ANTIGEN CLASS 2; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY;
EID: 0027371641     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/0952-7915(93)90114-8     Document Type: Article
Times cited : (37)
References (36)
  • 2
    • 0026443197 scopus 로고
    • T Cells and Eosinophils in the Pathogenesis of Asthma
    • of special interest, A lucid exposition of the current research, much of it published before 1992, that leads to the theory that T cells are the prime orchestrators of allergic inflammation.
    • (1992) Immunol Today , vol.13 , pp. 501-512
    • Corrigan1    Kay2
  • 11
    • 0005515721 scopus 로고
    • T Lymphocytes and the Pathogenesis of Bronchial Asthma: Studies Using the Techniques of in Situ Hybridization and Polymerase Chain Reaction cDNA Amplification
    • of special interest, S.T. Holgate, K.F. Austen, L.M. Lichtenstein, A.B. Kay, Academic Press, London, A good review. It contains some as yet unpublished data showing that corticosteroid treatment restores normal inflammatory cytokine mRNA expression in cells from biopsies of bronchial mucosa.
    • (1993) Asthma, Physiology, Immunopbarmacology, and Treatment Fourth International Symposium , pp. 153-162
    • Corrigan1    Hamid2    Kay3
  • 12
    • 0026603643 scopus 로고
    • Cytokine Messenger RNA Expression for IL-3, IL-4, IL-5, and Granulocyte/Macro phase-Colony-Stimulating Factor in the Nasal Mucosa after Local Allergen Provocation: Relationship to Tissue Eosinophilia
    • (1992) J Immunol , vol.148 , pp. 2390-2394
    • Durham1    Ying2    Varney3    Jacobson4    Sudderick5    MacKay6    Kay7    Hamid8
  • 17
    • 0027069438 scopus 로고
    • Role of Basophils in Human Disease
    • of special interest, Although attention tends to be focused on eosinophils in allergic inflammation, basophils are also present, although they are often missed because they require special stains. This review provides the reasons for the belief that basophils are important, even necessary, players in allergic inflammation.
    • (1992) Int Archives Allergy Immunol , vol.99 , pp. 184-188
    • Massey1    Lichtenstein2
  • 18
    • 0027164230 scopus 로고
    • The Importance of Th2-Like Cells in the Pathogenesis of Airway Allergic Inflammation
    • of special interest, This review outlines the evidence that the T cells that respond to allergens in allergic patients have a cytokine pattern similar to that of murine Th2 cells.
    • (1993) Clin Exp Allergy , vol.23 , pp. 360-369
    • Ricci1    Rossi2    Bertoni3    Matucci4
  • 21
    • 0027222095 scopus 로고
    • Influence of Grass Pollen Immunotherapy on Cellular Infiltration and Cytokine mRNA Expression During Allergen-Induced Late Phase Cutaneous Responses
    • + T cells responding to an allergen at the site of allergic inflammation are downregulated by standard immunotherapy. Unexpectedly, expression of mRNA for Th2 cytokines was not lower in treated patients than in placebo-treated controls, rather expression of IL-2 and IFN-γ was increased in some treated patients.
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney1    Hamid2    Gaga3    Ying4    Jacobson5    Frew6    Kay7    Durham8
  • 22
    • 0026542103 scopus 로고
    • Allergic Rhinitis to Ragweed Pollen. II. Modulation of Histamine Releasing Factor Production by Specific Immunotherapy
    • of special interest, The exact role of HRFs during in vivo late phase mediator release has yet to be established. If HRF is important, its production by macrophages is inhibited after immunotherapy.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 87-94
    • Brunet1    Bédard2    Lavoie3    Jobin4    Hébert5
  • 23
    • 0026695117 scopus 로고
    • The Effect of Immunotherapy on Interleukin-1 and Tumor Necrosis Factor Production of Monocytes in Asthmatic Children
    • (1992) J Asthma , vol.29 , pp. 193-201
    • Wang1    Lei2    Hsieh3
  • 24
    • 0022995766 scopus 로고
    • Serologic Aspects of IgG4 Antibodies. II. IgG4 Antibodies Form Small, Nonprecipitating, Immune Complexes due to Functional Monovalency
    • (1986) J Immunol , vol.137 , pp. 3566-3571
    • van der Zee1    van Swieten2    Aalberse3
  • 25
    • 0025910635 scopus 로고
    • The Role of IgG Subclass Antibodies in the Clinical Response to Immunotherapy in Allergic Disease
    • (1991) Clin Exp Allergy , vol.21 , pp. 289-296
    • Nakagawa1
  • 29
  • 34
    • 0027056539 scopus 로고
    • Amelioration of Autoimmune Encephalomyelitis by Myelin Basic Protein Synthetic Peptide4nduced Anergy
    • of special interest, Although EAE is not an allergic condition but rather an artificially induced autoimmune disease, neurological lesions come about through the action of T cells. These experiments show that amelioration of disease can be induced not only by pretreatment with a tolerizing regimen, but by treatment once the lesions have begun to develop. The induction of tolerance both before and after immunization correlates with downregulation of T-cell proliferation in the presence of antigen. Effective tolerizing regimens include administration of MBP itself and of a peptide from MBP that contains the T-cell epitope.
    • (1992) Science , vol.258 , pp. 1491-1494
    • Gaur1    Wiers2    Liu3    Rothbard4    Fathman5
  • 36
    • 0027323846 scopus 로고
    • Peripheral T-Cell Tolerance Induced in Naive and Primed Mice by Subcutaneous Injection of Peptides from the Major Cat Allergen Fel d I
    • of outstanding interest, This reports an important murine model for sensitization and tolerance to an antigen that is a common cause of human allergy. The peptides used for tolerization have been proposed for treatment of human cat allergy and preliminary trials are under way.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7608-7612
    • Briner1    Kuo2    Keating3    Rogers4

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.