Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases

Biochemical Pharmacology

Volumn 46, Issue 7, 1993, Pages 1285-1293

  Massolini, Gabriella ^a   Aubry, Anne Francoise ^a   Mcgann, Angela ^b   Wainer, Irving W ^a  

^a MCGILL UNIVERSITY   (Canada)

^b Shandon HPLC   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYALPRAZOLAM; ALPRAZOLAM; AMINO ACID; BENZODIAZEPINE DERIVATIVE; CLORAZEPATE; DICLOFENAC; DIFLUNISAL; FENOPROFEN; FLUFENAMIC ACID; FLURBIPROFEN; FOLINIC ACID; HUMAN SERUM ALBUMIN; IBUPROFEN; KETOPROFEN; LORMETAZEPAM; MEFENAMIC ACID; N BENZOYLPHENYLALANINE; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; OXAZEPAM; OXYPHENBUTAZONE; PHENYLBUTAZONE; PIROXICAM; SERUM ALBUMIN; SULFINPYRAZONE; SULINDAC; SUPROFEN; TEMAZEPAM; TRYPTOPHAN; UNCLASSIFIED DRUG; WARFARIN;

ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; RABBIT; RAT; SPECIES DIFFERENCE; STEREOSPECIFICITY; ULTRAFILTRATION;

ANIMAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZODIAZEPINONES; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; HUMAN; LIGANDS; OCTANOIC ACIDS; PROTEIN BINDING; RABBITS; RATS; SERUM ALBUMIN; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T; ULTRAFILTRATION; WARFARIN;

EID: 0027371531     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(93)90478-F     Document Type: Article

References (13)

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3. Stereoselective binding of the enantiomers of warfarin and tryptophan to serum albumin from some different species studied by affinity chromatography on columns of immobilized serum albumin
4. The use of human serum albumin based stationary phase for high performance liquid chromatography as a tool for the rapid determination of drug-plasma protein binding
5. Human serum albumin based chiral stationary phase for high performance liquid chromatography: A tool for the rapid study of drug-protein binding interactions
6. Synthesis and Chromatographic properties of an HPLC chiral stationary phase based upon human serum albumin
7. Immobilized serum albumin: A rapid probe of Stereoselective protein binding interactions
8. Stereochemical resolution of enantiomeric 2-aryl propionic acid non-steroidal anti-inflammatory drugs on a human albumin based high-performance liquid Chromatographic chiral stationary phase
9. Stereochemical aspects of benzodiazepine binding to human serum albumin. II. Quantitative relationships between structure and enantioselective retention in high performance liquid affinity chromatography
10. Determination of drug protein-binding by high-performance liquid chromatography using a chemically bonded bovine serum albumin stationary phase
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12. Specificity of binding sites on plasma proteins
13. Stereochemical aspects of benzodiazepine binding to human serum albumin. I. Enantioselective high performance liquid affinity Chromatographie examination of chiral and achiral binding interactions between 1,4-benzodiazepines and human serum albumin