Use of pharmacological agents to implicate a role for phosphoinositide hydrolysis products in malaria gamete formation

Biochemical Pharmacology

Volumn 46, Issue 9, 1993, Pages 1601-1606

  Ogwan'g, Rose ^a   Mwangi, Josephat ^a   Gachihi, George ^a   Nwachukwu, Aba ^b   Roberts, Clifford R ^a,c   Martin, Samuel K ^a,c  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; BICARBONATE; CAFFEINE; CALCIMYCIN; CALCIUM; CHLOROQUINE; DIACYLGLYCEROL; GENTAMICIN; INOSITOL TRISPHOSPHATE; MAGNESIUM; PHOSPHOLIPASE A; PHOSPHOLIPASE C; QUININE; THEOBROMINE; THEOPHYLLINE;

ANIMAL CELL; ARTICLE; GAMETOCYTE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

2,3-DIPHOSPHOGLYCERATE; ANIMAL; CAFFEINE; CALCIUM; DIGLYCERIDES; DIPHOSPHOGLYCERIC ACIDS; GENTAMICINS; MAGNESIUM; MALARIA; PHOSPHATIDYLINOSITOLS; PHOSPHORIC MONOESTER HYDROLASES; PLASMODIUM FALCIPARUM; SIGNAL TRANSDUCTION; THEOBROMINE; XANTHINES;

EID: 0027368938     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(93)90329-U     Document Type: Article

References (27)

1. Cultivation of parasites in vitro with special reference to differentiation in the life cycle
2. Factors affecting exflagellation of in vitro cultivated Plasmodium falciparum gametocytes
3. Turnover of inositol phospholipids and signal transduction
4. Inositol phospholipids and neuro-transmitter-receptor signaling mechanisms
5. Characterization of inositol trisphosphate receptor binding in brain
6. 2+ mobilization and granule secretion in platelets
7. 2+ release from permeabilized hepatocytes
8. Inositol phosphates and cell signaling
9. Diacylglycerol and phorbol ester stimulate secretion without raising cytosplasmic free calcium in human platelets
10. The role of protein kinase-C in cell surface signal transduction and tumor promotion
11. Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide-generation from human neutrophils
12. Inositol phosphates: synthesis and degradation
13. Inositol 1,4,5-trisphosphate phosphotase deficiency and malignant hyperpyrexia in swine
14. + channels
15. Solubilization, purification, and characterization of an inositol trisphosphate receptor
16. Inhibition by neomycin of poly-phosphoinositide turnover in subcellular fractions of guinea-pig cerebral cortex in vitro
17. Plasmodium berghei: production in vitro of free fatty acids
18. Human malaria parasites in continuous culture
19. Inhibition of phos-phatidylinositol phosphodiesterase activity in skeletal muscle by metal ions and drugs which block neuromuscular transmission
20. Complete in vitro maturation of falciparum gametocytes
21. The polyphosphoinositide phosphodiesterase of erythrocyte membranes
22. Plasmodium gallinaceum: induction of male gametocyte exflagellation by phosphodiesterase inhibitors
23. 2+ and cGMP as mediators of exflagellation of and Plasmodium falciparum
24. Inositol 1,4,5 trisphosphate: a possible chemical link in excitation- contraction coupling in muscle