메뉴 건너뛰기




Volumn 55, Issue 1, 1993, Pages 1-8

The mechanism of hepatic cellular injury in sepsis: An in vitro study of the implications of cytokines and neutrophils in its pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0027366245     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1993.1100     Document Type: Article
Times cited : (28)

References (57)
  • 2
    • 0022551927 scopus 로고
    • Hepa-tocyte function in sepsis: Kupffer cells mediate a biphasic protein synthesis response in hepatocytes after exposure to endotoxin or killed
    • West, M. A., Keller, G. A., Hyland, B. J., and Cerra, F. B. Hepa-tocyte function in sepsis: Kupffer cells mediate a biphasic protein synthesis response in hepatocytes after exposure to endotoxin or killed Escherichia coli. Surgery 100: 416, 1986.
    • (1986) Escherichia Coli. Surgery , vol.100 , pp. 416
    • West, M.A.1    Keller, G.A.2    Hyland, B.J.3    Cerra, F.B.4
  • 3
    • 0022519383 scopus 로고
    • Acute generalized microvascu-lar injury by activated complement and hypoxia: The basis of the adult respiratory distress syndrome and multiple organ failure
    • Nuytinck, J. K. S., Goris, R. J. A., Weerts, J. G. E., Schillings, P. H. M., and Stekhoven, J. H. S. Acute generalized microvascu-lar injury by activated complement and hypoxia: The basis of the adult respiratory distress syndrome and multiple organ failure? Br. J. Exp. Pathol. 67: 537, 1986.
    • (1986) Br. J. Exp. Pathol. , vol.67 , pp. 537
    • Nuytinck, J.K.S.1    Goris, R.J.A.2    Weerts, J.G.E.3    Schillings, P.H.M.4    Stekhoven, J.H.S.5
  • 5
    • 0024599440 scopus 로고
    • Hepatic dysfunction in the adult respiratory distress syndrome
    • Schwartz, D. B., Bone, R. C., Balk, R. A., and Szidon, J. P. Hepatic dysfunction in the adult respiratory distress syndrome. Chest 95: 871, 1989.
    • (1989) Chest , vol.95 , pp. 871
    • Schwartz, D.B.1    Bone, R.C.2    Balk, R.A.3    Szidon, J.P.4
  • 6
    • 0019985443 scopus 로고
    • Hepatic cellular injury following lethal Escherichia coli bacteremia in rats
    • Sato, T., Tanaka, J., Kono, Y., Jones, R. T., Cowley, R. A., and Trump, B. F. Hepatic cellular injury following lethal Escherichia coli bacteremia in rats. Lab. Invest. 47: 304, 1982.
    • (1982) Lab. Invest. , vol.47 , pp. 304
    • Sato, T.1    Tanaka, J.2    Kono, Y.3    Jones, R.T.4    Cowley, R.A.5    Trump, B.F.6
  • 7
    • 0022620180 scopus 로고
    • Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance
    • Weiland, J. E., Davis, W. B., Holter, J. F., Mohammed, J. R., Dorinsky, P. M., and Gadek, J. E. Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance, Am. Rev. Respir. Dis. 133: 218, 1986.
    • (1986) Am. Rev. Respir. Dis. , vol.133 , pp. 218
    • Weiland, J.E.1    Davis, W.B.2    Holter, J.F.3    Mohammed, J.R.4    Dorinsky, P.M.5    Gadek, J.E.6
  • 8
    • 0024425809 scopus 로고
    • Roles of the neutrophil and other mediators in adult respiratory distress syndrome
    • Swank, D. W., and Moore, S. B. Roles of the neutrophil and other mediators in adult respiratory distress syndrome. Mayo Clin. Proc. 64: 1118, 1989.
    • (1989) Mayo Clin. Proc. , vol.64 , pp. 1118
    • Swank, D.W.1    Moore, S.B.2
  • 9
    • 0025279912 scopus 로고
    • The adult respiratory distress syndrome: Definition and prognosis, pathogenesis and treatment
    • Wiener-Kronish, J. P., Gropper, M. A., and Matthay, M. A. The adult respiratory distress syndrome: Definition and prognosis, pathogenesis and treatment. Br. J. Anaesth. 65: 107, 1990.
    • (1990) Br. J. Anaesth. , vol.65 , pp. 107
    • Wiener-Kronish, J.P.1    Gropper, M.A.2    Matthay, M.A.3
  • 10
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss, S. J. Tissue destruction by neutrophils. N. Engl. J. Med. 320: 365, 1989.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 365
    • Weiss, S.J.1
  • 14
    • 0018941793 scopus 로고
    • Effect of granulocytopenia on ex-travascular lung water content after microembolization
    • Johnson, A., and Malik, A. B. Effect of granulocytopenia on ex-travascular lung water content after microembolization. Am. Rev. Respir. Dis. 122: 561, 1980.
    • (1980) Am. Rev. Respir. Dis , vol.122 , pp. 561
    • Johnson, A.1    Malik, A.B.2
  • 15
    • 0019846903 scopus 로고
    • Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia
    • Heflin, A. C., Jr., and Brigham, K. L. Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J. Clin. Invest. 68: 1253, 1981.
    • (1981) J. Clin. Invest. , vol.68 , pp. 1253
    • Heflin, A.C.1    Brigham, K.L.2
  • 16
    • 0019482711 scopus 로고
    • Leukocytes are required for increased lung microvascular permeability after microembolization in sheep
    • Flick, M. R., Perel, A., and Staub, N. C. Leukocytes are required for increased lung microvascular permeability after microembolization in sheep. Circ. Res. 48: 344, 1981.
    • (1981) Circ. Res. , vol.48 , pp. 344
    • Flick, M.R.1    Perel, A.2    Staub, N.C.3
  • 17
    • 0019992734 scopus 로고
    • Reduction of the edema of acute hyperoxic lung injury by granulocyte depletion
    • Shasby, D. M., Fox, R. B., Harada, R. N., and Repine, J. E. Reduction of the edema of acute hyperoxic lung injury by granulocyte depletion. J. Appl. Physiol. 52: 1237, 1982.
    • (1982) J. Appl. Physiol , vol.52 , pp. 1237
    • Shasby, D.M.1    Fox, R.B.2    Harada, R.N.3    Repine, J.E.4
  • 18
    • 0024360219 scopus 로고
    • Multiple organ damage caused by tumor necrosis factor and prevented by prior neutrophil depletion
    • Mallick, A. A., Ishizaka, A., Stephens, K. E., Hatherill, J. R., Tazelaar, H. D., and Raffin, T. A. Multiple organ damage caused by tumor necrosis factor and prevented by prior neutrophil depletion. Chest 95: 1114, 1989.
    • (1989) Chest , vol.95 , pp. 1114
    • Mallick, A.A.1    Ishizaka, A.2    Stephens, K.E.3    Hatherill, J.R.4    Tazelaar, H.D.5    Raffin, T.A.6
  • 19
    • 0023695958 scopus 로고
    • Release of pancreatic secretory trypsin inhibitor from human hepatoblastoma cells on stimulation with cytokines
    • Murata, A., Ogawa, M., Uda, K., Matsuura, N., Watanabe, Y., Baba, T., and Mori, T. Release of pancreatic secretory trypsin inhibitor from human hepatoblastoma cells on stimulation with cytokines. Life Sci. 43: 1233, 1988.
    • (1988) Life Sci , vol.43 , pp. 1233
    • Murata, A.1    Ogawa, M.2    Uda, K.3    Matsuura, N.4    Watanabe, Y.5    Baba, T.6    Mori, T.7
  • 20
    • 0025175524 scopus 로고
    • Response to IL-6 stimulation of human hepatoblastoma cells: Production of pancreatic secretory trypsin inhibitor
    • Yasuda, T., Ogawa, M., Murata, A., Oka, Y., Uda, K., and Mori, T. Response to IL-6 stimulation of human hepatoblastoma cells: Production of pancreatic secretory trypsin inhibitor. Biochem. J. Hoppe-Seykr’s 371(Suppl.): 95, 1990.
    • (1990) Biochem. J. Hoppe-Seykr’s , vol.371 , pp. 95
    • Yasuda, T.1    Ogawa, M.2    Murata, A.3    Oka, Y.4    Uda, K.5    Mori, T.6
  • 21
    • 0020398242 scopus 로고
    • Human granulocyte elastase is inhibited by the urinary trypsin inhibitor
    • Jönson, B.-M., Löffler, C., and Ohlsson, K. Human granulocyte elastase is inhibited by the urinary trypsin inhibitor. Hoppe-Seyler’s Z. Physiol. Chem. 363(Suppl.): 1167, 1982.
    • (1982) Hoppe-Seyler’s Z. Physiol. Chem , vol.363 , pp. 1167
    • Jönson, B.-M.1    Löffler, C.2    Ohlsson, K.3
  • 23
    • 0021332228 scopus 로고
    • Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis
    • Ohnishi, H., Kosuzume, H., Ashida, Y., Kato, K., and Honjo, I. Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis. Dig. Dis. Sci. 29: 26, 1984.
    • (1984) Dig. Dis. Sci. , vol.29 , pp. 26
    • Ohnishi, H.1    Kosuzume, H.2    Ashida, Y.3    Kato, K.4    Honjo, I.5
  • 24
    • 0042864627 scopus 로고
    • The effects of Ulinastatin on cardiac and hepatic energy metabolism in rats subjected to hypovolemic shock
    • Kashimoto, S., Nakagomi, M., Nonaka, A., and Kumazawa, T. The effects of Ulinastatin on cardiac and hepatic energy metabolism in rats subjected to hypovolemic shock. J. Anesth. 4: 40, 1990.
    • (1990) J. Anesth. , vol.4 , pp. 40
    • Kashimoto, S.1    Nakagomi, M.2    Nonaka, A.3    Kumazawa, T.4
  • 25
    • 0017260918 scopus 로고
    • Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma
    • Doi, I. Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma. Gann 67: 1, 1976.
    • (1976) Gann , vol.67 , pp. 1
    • Doi, I.1
  • 26
    • 84941842238 scopus 로고
    • PMN-elastase assay: Enzyme immunoassay for human polymorphonuclear elastase in complex with a 1-proteinase inhibitor
    • Neumann, S., Gunzer, G., Hennrich, N., and Lang, H. “PMN-elastase assay”: Enzyme immunoassay for human polymorphonuclear elastase in complex with a 1-proteinase inhibitor. J. Clin. Chem. Clin. Biochem. 22: 693, 1984.
    • (1984) J. Clin. Chem. Clin. Biochem. , vol.22 , pp. 693
    • Neumann, S.1    Gunzer, G.2    Hennrich, N.3    Lang, H.4
  • 28
    • 0025765623 scopus 로고
    • Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines
    • Mackiewicz, A., Speroff, T., Ganapathi, M. K., and Kushner, I. Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines. J. Immunol. 146: 3032, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 3032
    • Mackiewicz, A.1    Speroff, T.2    Ganapathi, M.K.3    Kushner, I.4
  • 29
    • 0014978020 scopus 로고
    • Albumin standards and the measurement of serum albumin with bromcresol green
    • Doumas, B. T., Watson, W. A., and Biggs, H. G. Albumin standards and the measurement of serum albumin with bromcresol green. Clin. Chim. Acta 31: 87, 1971.
    • (1971) Clin. Chim. Acta , vol.31 , pp. 87
    • Doumas, B.T.1    Watson, W.A.2    Biggs, H.G.3
  • 30
    • 0018851290 scopus 로고
    • Radioimmunoassay for human pancreatic secretory trypsin inhibitor: Measurement of serum pancreatic secretory trypsin inhibitor in normal subjects and subjects with pancreatic diseases
    • Kitahara, T., Takatsuka, Y., Fujimoto, K., Tanaka, S., Ogawa, M., and Kosaki, G. Radioimmunoassay for human pancreatic secretory trypsin inhibitor: Measurement of serum pancreatic secretory trypsin inhibitor in normal subjects and subjects with pancreatic diseases. Clin. Chim. Acta 103: 135, 1980.
    • (1980) Clin. Chim. Acta , vol.103 , pp. 135
    • Kitahara, T.1    Takatsuka, Y.2    Fujimoto, K.3    Tanaka, S.4    Ogawa, M.5    Kosaki, G.6
  • 31
    • 0024451836 scopus 로고
    • Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans
    • Damas, P., Reuter, A., Gysen, P., Demonty, J., Lamy, M., and Franchimont, P. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit. Care Med. 17: 975, 1989.
    • (1989) Crit. Care Med. , vol.17 , pp. 975
    • Damas, P.1    Reuter, A.2    Gysen, P.3    Demonty, J.4    Lamy, M.5    Franchimont, P.6
  • 32
    • 0025340431 scopus 로고
    • Serum interleukin 6, C-reactiveprotein and pancreatic secretory trypsin inhibitor (PSTI) as acute phase reactants after major thor-aco-abdominal surgery
    • Murata, A., Ogawa, M., Yasuda, T., Nishijima, J., Oka, Y., Oh-machi, Y., Hiraoka, N., Niinobu, T., Uda, K., and Mori, T. Serum interleukin 6, C-reactive protein and pancreatic secretory trypsin inhibitor (PSTI) as acute phase reactants after major thor-aco-abdominal surgery. Immunol. Invest. 19: 271, 1990.
    • (1990) Immunol. Invest. , vol.19 , pp. 271
    • Murata, A.1    Ogawa, M.2    Yasuda, T.3    Nishijima, J.4    Oka, Y.5    Oh-Machi, Y.6    Hiraoka, N.7    Niinobu, T.8    Uda, K.9    Mori, T.10
  • 33
    • 0023671596 scopus 로고
    • The role of cachectin/TNF in endo-toxic shock and cachexia
    • Cerami, A., and Beutler, B. The role of cachectin/TNF in endo-toxic shock and cachexia. Immunol. Today 9: 28, 1988.
    • (1988) Immunol. Today , vol.9 , pp. 28
    • Cerami, A.1    Beutler, B.2
  • 34
    • 0023041566 scopus 로고
    • Tumor necrosis factor as an immune modulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1
    • Ramila, P., and Epstein, L. B. Tumor necrosis factor as an immune modulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1. Nature 323: 86, 1986.
    • (1986) Nature , vol.323 , pp. 86
    • Ramila, P.1    Epstein, L.B.2
  • 35
    • 0024586781 scopus 로고
    • Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells
    • Jirik, F. R., Podor, T. J., Hirano, T., Kishimoto, T., Loskutoff, D. J., Carson, D. A., and Lotz, M. Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J. Immunol. 142: 144, 1989.
    • (1989) J. Immunol. , vol.142 , pp. 144
    • Jirik, F.R.1    Podor, T.J.2    Hirano, T.3    Kishimoto, T.4    Loskutoff, D.J.5    Carson, D.A.6    Lotz, M.7
  • 36
    • 0025283377 scopus 로고
    • IL-1 and tumor necrosis factor syner-gistically stimulate fibroblast IL-6 production and stabilize IL-6 messenger RNA
    • Elias, J. A., and Lentz, V. IL-1 and tumor necrosis factor syner-gistically stimulate fibroblast IL-6 production and stabilize IL-6 messenger RNA. J. Immunol. 145: 161, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 161
    • Elias, J.A.1    Lentz, V.2
  • 38
    • 0024421453 scopus 로고
    • Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils
    • Baggiolini, M., Walz, A., and Kunkel, S. L. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J. Clin. Invest. 84: 1045, 1989.
    • (1989) J. Clin. Invest , vol.84 , pp. 1045
    • Baggiolini, M.1    Walz, A.2    Kunkel, S.L.3
  • 39
    • 0019966544 scopus 로고
    • Growth of human hepatoma cell lines with differentiated functions in chemically defined medium
    • Nakabayashi, H., Taketa, K., Miyano, K., Yamane, T., and Sato, J. Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res. 42: 3858, 1982.
    • (1982) Cancer Res , vol.42 , pp. 3858
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 40
    • 0022405364 scopus 로고
    • Hormonal control of a-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined medium
    • Nakabayashi, H., Taketa, K., Yamane, T., Oda, M., and Sato, J. Hormonal control of a-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined medium. Cancer Res. 45: 6379, 1985.
    • (1985) Cancer Res , vol.45 , pp. 6379
    • Nakabayashi, H.1    Taketa, K.2    Yamane, T.3    Oda, M.4    Sato, J.5
  • 43
    • 0023754651 scopus 로고
    • Pancreatic secretory trypsin inhibitor as an acute phase reactant
    • Ogawa, M. Pancreatic secretory trypsin inhibitor as an acute phase reactant. Clin. Biochem. 21: 19, 1988.
    • (1988) Clin. Biochem. , vol.21 , pp. 19
    • Ogawa, M.1
  • 44
    • 0024197686 scopus 로고
    • Serum pancreatic secretory trypsin inhibitor (PSTI) in patients with inflammatory diseases
    • Ogawa, M., Shibata, T., Niinobu, T., Uda, K., Takata, N., and Mori, T. Serum pancreatic secretory trypsin inhibitor (PSTI) in patients with inflammatory diseases. Adv. Exp. Med. Biol. 240: 505, 1988.
    • (1988) Adv. Exp. Med. Biol. , vol.240 , pp. 505
    • Ogawa, M.1    Shibata, T.2    Niinobu, T.3    Uda, K.4    Takata, N.5    Mori, T.6
  • 46
    • 0024814903 scopus 로고
    • Interleukin 6: A multifunctional cytokine regulating immune reactions and the acute phase protein response
    • Le, J., and Vilcek, J. Interleukin 6: A multifunctional cytokine regulating immune reactions and the acute phase protein response. Lab. Invest. 61: 588, 1989.
    • (1989) Lab. Invest. , vol.61 , pp. 588
    • Le, J.1    Vilcek, J.2
  • 47
    • 0013789330 scopus 로고
    • The effect on the liver of sensitized rats of intravenous injection of antigen
    • Blackwell, J. B. The effect on the liver of sensitized rats of intravenous injection of antigen. J. Pathol. Bacterial. 90: 259, 1965.
    • (1965) J. Pathol. Bacterial. , vol.90 , pp. 259
    • Blackwell, J.B.1
  • 49
    • 0018412371 scopus 로고
    • Glucocorticoid and antibiotic effects on hepatic microcirculation and associated host responses in lethal gram-negative bacteremia
    • Balis, J. U., Paterson, J. F., Shelley, S. A., Larson, C. H., Fareed, J., and Gerber, L. I. Glucocorticoid and antibiotic effects on hepatic microcirculation and associated host responses in lethal gram-negative bacteremia. Lab. Invest. 40: 55, 1979.
    • (1979) Lab. Invest. , vol.40 , pp. 55
    • Balis, J.U.1    Paterson, J.F.2    Shelley, S.A.3    Larson, C.H.4    Fareed, J.5    Gerber, L.I.6
  • 50
    • 0021311432 scopus 로고
    • Physiology and pathophysiology of neutral proteinases of human granulocytes
    • Havemann, K., and Gramse, M. Physiology and pathophysiology of neutral proteinases of human granulocytes. Adv. Exp. Med. Biol. 167: 1, 1984.
    • (1984) Adv. Exp. Med. Biol. , vol.167 , pp. 1
    • Havemann, K.1    Gramse, M.2
  • 52
    • 0021941090 scopus 로고
    • Elastase in tissue injury
    • Aaron, J. Elastase in tissue injury. Ann. Rev. Med. 36: 207, 1985.
    • (1985) Ann. Rev. Med. , vol.36 , pp. 207
    • Aaron, J.1
  • 55
    • 0022658552 scopus 로고
    • Neutrophil-mediated solubilization of the subendothelial matrix: Oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes
    • Weiss, S. J., Curnutte, J. T., and Regiani, S. Neutrophil-mediated solubilization of the subendothelial matrix: Oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes. J. Immunol. 136: 636, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 636
    • Weiss, S.J.1    Curnutte, J.T.2    Regiani, S.3
  • 56
    • 0026021473 scopus 로고
    • Effects of cytokines on the liver
    • Andus, T., Bauer, J., and Gerok, W. Effects of cytokines on the liver. Hepatology 13: 364, 1991.
    • (1991) Hepatology , vol.13 , pp. 364
    • Andus, T.1    Bauer, J.2    Gerok, W.3
  • 57
    • 0023886405 scopus 로고
    • Hepatocyte injury during post-operative sepsis: Activatedneutrophils as potential mediators
    • Holman, J. M., Jr., and Saba, T. M. Hepatocyte injury during post-operative sepsis: Activated neutrophils as potential mediators. J. Leukoc. Biol. 43: 193, 1988.
    • (1988) J. Leukoc. Biol. , vol.43 , pp. 193
    • Holman, J.M.1    Saba, T.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.