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Volumn 23, Issue 11, 1993, Pages 2834-2840

The lack of CD8α cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes

(10) Fung‐Leung, Wai‐Ping a Louie, Marjorie C a Limmer, Andreas a Ohashi, Pamela S a Ngo, Karen a Chen, Lei a Kawai, Kazuhiro b Lacy, Elizabeth a Loh, Dennis Y c Mak, Tak W d

a UNIVERSITY OF TORONTO (Canada)

b R W Johnson Pharmaceutical Research Institute ^* (Canada)

c WASHINGTON UNIVERSITY (United States)

d Department of Obstetrics Gynecology (United States)

Author keywords

CD8; Gene targeted mice; T cell function; T cell ontogeny; Transgenic mice

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MATURATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE;

ANIMAL; ANTIGENS, CD8; BASE SEQUENCE; CELL DIFFERENTIATION; CYTOPLASM; DNA; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; SEQUENCE DELETION; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0027366168 PISSN: 00142980 EISSN: 15214141 Source Type: Journal
DOI: 10.1002/eji.1830231117 Document Type: Article

Times cited : (45)

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