A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome

Journal of Clinical Investigation

Volumn 92, Issue 5, 1993, Pages 2110-2116

  Harel, Y ^a   Silva, M ^a   Giroir, B ^a   Weinberg, A ^a   Cleary, T B ^a   Beutler, B ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

cytokine; exotoxin; hemolytic uremic syndrome; kidney; transgenic mouse

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHLORAMPHENICOL ACETYLTRANSFERASE; TUMOR NECROSIS FACTOR; VEROTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEMOLYTIC UREMIC SYNDROME; HISTOPATHOLOGY; LETHAL DOSE; MOUSE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REPORTER GENE; SENSITIZATION; TRANSGENIC MOUSE;

EID: 0027363238     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116811     Document Type: Article

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