Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

Cell

Volumn 75, Issue 4, 1993, Pages 631-639

  Dietrich, William F ^a   Lander, Eric S ^a   Smith, Jennifer S ^a   Moser, Amy R ^c   Gould, Karen A ^b,c   Luongo, Cindy ^b,c   Borenstein, Natalie ^c   Dove, William ^b,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER GENETICS; COLON CANCER; COLON TUMOR; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENE MUTATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ANIMAL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; COLONIC NEOPLASMS; COMPARATIVE STUDY; GENES, DOMINANT; GENES, TUMOR SUPPRESSOR; HUMAN; MICE; MICE, MUTANT STRAINS; NEOPLASMS, EXPERIMENTAL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027363063     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(93)90484-8     Document Type: Article

References (48)

1. Mapping the gene for hereditary cutaneous malignant melanoma-dysplastic nevus to chromosome 1p
2. Genetic epidemiology of cancer in Utah geneologies a prelude to the molecular genetics of common cancers
3. A general method for isolation of high molecular weight DNA from eukaryotes
4. A gene with major effect on susceptibility to induced lung tumors in mice
5. Localization of the gene for familial adenomatous polyposis on chromosome 5
6. Familial polyposis coli
7. Gastrointestinal cancer
8. Report of the committee on methods of linkage analysis and reporting
9. Development and applications of a molecular genetic linkage map of the mouse genome
10. A genetic map of the mouse suitable for typing intraspecific crosses
11. SSLP genetic map of the mouse (Mus musculus) 2N = 40, July, 1992
12. Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a highly related sequence to chromosome 15
13. Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development
14. Identification and characterization of the familial adenomatous polyposis coli gene
15. Histopathologic considerations in the adenoma-carcinoma sequence
16. Genetics of cancer predisposition
17. Tumor development in susceptible strain A and resistant strain L lung transplants in LA F1 hosts
18. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat
19. Promotion of murine hepatocarcinogenesis by testosterone is androgen receptor-dependent but not cell autonomous
20. Identification of FAP locus genes from chromosome 5q21
21. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
22. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
23. Human colorectal cancer: high frequency of deletions at chromosome 1p35
24. The gene for familial polyposis coli maps to the long arm of chromosome 5
25. Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps
26. Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse
27. Colon cancer genetics
28. Hereditary flat adenoma syndrome: a variant of familial adenomatous polyposis?
29. Localization of a lymphocyte-specific protein tyrosine kinase gene (LCK) at a site of frequent chromosomal abnormalities in human lymphomas
30. Deletion of genes on chromosome 1 in endocrine neoplasia
31. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
32. The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system
33. Min, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
34. Comparative map for mice and humans
35. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
36. Resolution of quantitative traits into Mendelian factors by using a complete RFLP linkage map
37. Mendelian factors underlying quantitative traits in tomato: comparison across species, generations, and environments
38. Intrinsic tissue response to induction of pulmonary tumors
39. Mouse models of human phenylketonuria
40. Animal models of human genetic diseases
41. PCR amplification of specific alleles (PASA) is a general method for rapidly detecting known single-base changes
42. Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus
43. A germline mutation of the murine homolog of the APC gene causes multiple intestinal neoplasia
44. The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and mouse chromosome 4