Vasoactive intestinal peptide downregulates the expression of IL-2 but not of IFNγ from stimulated murine T lymphocytes

Journal of Neuroimmunology

Volumn 47, Issue 2, 1993, Pages 147-158

  Ganea, Doina ^a   Lei, Sun ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Immunosuppression; Interferon gamma; Interleukin 2; Vasoactive intestinal peptide

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; GLUCAGON; PHORBOL ESTER; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 4; SECRETIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMAL; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CONCANAVALIN A; CYCLIC AMP; FEMALE; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; SPLEEN; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0027361023     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-5728(93)90025-T     Document Type: Article

References (64)

1. Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2Ra gene expression at multiple levels
2. Demonstration of a functional receptor for vasoactive intestinal polypeptide on Molt 4b T lymphoblasts
3. Murine mucosal T cells have VIP receptors functionally distinct from those on intestinal epithelial cells
4. Dual effects of vasoactive intestinal peptide (VIP) on leucocyte migration
5. Inhibition of mouse T cell proliferation by CGRP and VIP: effects of these neuropeptides on IL-2 production and cAMP synthesis
6. Interaction of vasoactive intestinal peptide (VIP with rat lymphoid cells
7. Single step method of isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
8. Specific binding sites for vasoactive intestinal peptide on nonadherent peripheral blood lymphocytes
9. Inhibition of cytokine production by cyclosporin A and transforming growth factor β
10. The biochemistry, biology and role of IL-2 in the induction of cytotoxic T cells and antibody-forming B cell response
11. Noradrenergic and peptidergic innervation of lymphoid tissue
12. High-affinity receptors for VIP on human myeloma cells
13. Multiple neuropeptides in nerves supplying mammalian lymph nodes: messenger candidates for sensory and autonomic neurotransmission
14. Peptides and histamine release
15. Unique pattern of cleavage of vasoactive intestinal peptide by human lymphocytes
16. Demonstration of immunoreactive vasoactive intestinal peptide (IR-VIP) and somatostatin (IR-SOM) in rat thymus
17. Occurrence of vasoactive intestinal peptide (VIP) in lymphoid organs from rat and mouse
18. VIP: molecular biology and neurobiological function
19. Lymphokine and nonlymphokine mRNA levels in stimulated human T cells
20. Interaction of vasoactive intestinal peptide with human blood mononuclear cells
21. Human T cell activation. Monocyte-independent activation and proliferation induced by a T3 monoclonal antibody in the presence of tumor promoter 12-o-tetradecanoyl phorbol-13-acetate
22. Molecular events involved in regulating human interferon-gamma gene expression during T cell activation
23. Physiological and pathophysiological roles of VIP, somatostatin, opioids, galanin, GRP, and secretin
24. Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol triphosphate and cytoplasmic free calcium
25. Release of histamine from mast cells by vasoactive peptides
26. Phorbol ester replacement of helper cell and interleukin-2 requirements in γ-interferon production
27. Vasoactive intestinal peptide stimulates T lymphocytes to release IL-5 in murine schistosomiasis mansoni infection
28. Gastroenteropancreatic regulatory peptide structures
29. Modification of lymphocyte traffic by vasoactive neurotransmitter substances
30. Depression of lymphocyte traffic in sheep by vasoactive intestinal peptide (VIP)
31. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
32. Two types of murine helper T cell clone. Definition according to profiles of lymphokine activities and secreted proteins
33. The neuroimmune link in the bronchus-associated lymphoid tissue (BALT) of cat and rat: peptides and neural markers
34. cAMP inhibits induction of interleukin 2 but not interleukin 4 in T cells
35. Biochemical characterization of receptors for VIP in nervous, endocrine, and immune systems
36. Vasoactive intestinal polypeptide stimulation of adenylate cyclase in purified human leukocuytes
37. Cyclic AMP-dependent protein kinase in MOLT 4B lymphoblasts: identification by photoaffinity labeling and activation in intact cells by vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI)
38. Identification of high affinity receptors for vasoactive intestinal peptide on human lymphocytes of B cell lineage
39. In vitro alterations of receptors for vasoactive intestinal peptide changes the in vivo localization of mouse T cells
40. Evidence for local neuromodulation of T cell migration in vivo
41. Selective effects of vasoactive intestinal peptide on the mitogenic response to murine T cells
42. Interaction of vasoactive intestinal peptide with mouse lymphoccytes: specific binding and the modulation of mitogen response
43. Specific binding of vasoactive intestinal peptide to human circulating mononuclear cells
44. Vasoactive intestinal peptide-containing nerves in Peyer's patches
45. Control of IL-2 receptor a expression by IL-1, tumor necrosis factor and IL-2
46. Immunoregulatory effects of neuropeptides. Stimulation of interleukin-2 production by substance P
47. Variable stimulation of adenylate cyclase activity by vasoactive intestinal-like peptide and β-adrenergic agonist in murine T-cell lymphomas of immature, helper, and cytotoxic types
48. Human intraepithelial lymphocytes. Immunomodulation and receptor binding of vasoactive intestinal peptide
49. The effects of VIP on NK cell function
50. CD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis. Relationship to vasoactive intestinal peptide
51. Vasoactive intestinal peptide: current status
52. Vasoactive intestinal peptide
53. Vasoactive intestinal peptide and related peptides
54. Immune (Gamma) interferon production by a murine T cell lymphoma: requirements for macromolecular synthesis and lack of relationship with cell cycle
55. Characterization of functional receptors for vasoactive intestinal peptide (VIP) in rat peritoneal macrophages
56. Stimulatory effect of vasoactive intestinal peptide (VIP) on cyclic AMP production in rat peritoneal macrophages
57. Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferation by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen
58. Interferon inducibility in mice treated with Corynebacterium parvum
59. An improved colorimetric assay for interleukin 2
60. Vasoactive intestinal peptide Messenger in a neuroimmune axis
61. Vasoactive intestinal peptide inhibits the respiratory burst in human monocytes by a cyclic AMP-mediated mechanism
62. Binding of vasoactive intestinal peptide (VIP) by human blood monocytes: demonstration of specific binding sites
63. Covalent cross-linking of vasoactive intestinal polypeptide to its receptors on intact human lymphoblasts
64. Interferon-γ: producer cells, activation stimuli, and molecular genetic regulation