Cultured human liver fat-storing cells produce monocyte chemotactic protein-1 regulation by proinflammatory cytokines

Journal of Clinical Investigation

Volumn 92, Issue 4, 1993, Pages 1674-1680

  Marra, Fabio ^a   Valante, Anthony J ^a   Pinzani, Massimo ^b   Abboud, Hanna E ^a  

^a UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Interferon ; Interleukin 1 ; Platelet derived growth factor; Protein kinase C; Tumor necrosis factor

Indexed keywords

CHEMOTACTIC FACTOR; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1ALPHA; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHEMOTAXIS; CHRONIC ACTIVE HEPATITIS; HUMAN; HUMAN TISSUE; INFLAMMATORY INFILTRATE; LIVER CELL; MONOCYTE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SECRETION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADIPOCYTES; BLOTTING, NORTHERN; CELLS, CULTURED; CHEMOTACTIC FACTORS; CYTOKINES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; HUMAN; INFLAMMATION; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-1; ISOQUINOLINES; LIVER; MOLECULAR WEIGHT; MONOCYTE CHEMOATTRACTANT PROTEIN-1; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; RADIOIMMUNOASSAY; RECOMBINANT PROTEINS; RNA, MESSENGER; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE CULTURE; TUMOR NECROSIS FACTOR;

EID: 0027360267     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116753     Document Type: Article

References (21)

1. Perrillo, R. P. 1992. Chronic hepatitis. In Diseases of the Liver and the Biliary Tract, G. Gitnick, D. R. LaBrecque, and F. G. Moody. editors. Mosby-Year Book, Inc., St. Louis, 249-310.
2. Oppenheim, J. J., C. O. C. Zachariae, N. Mukaida, and K. Matsushima. 1991. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu Rev. Immunol. 9:617-648.
3. Yoshimura, T., and E. J. Leonard. 1990. Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. J. Immunol. 145:292-297.
4. Valente, A. J., D. T. Graves, C. E. Vialle-Valentin, R. Delgado, and C. J. Schwartz. 1988. Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture. Biochemistry. 27:4162-4168.
5. Graves, D. T., Y. L. Jiang, M. J. Williamson, and A. J. Valente. 1989. Identification of monocyte chemotactic activity produced by malignant cells. Science (Wash. DC). 245:1490-1493.
6. Navab, M., S. S. Imes, S. J. Hama, G. P. Hough, L. A. Ross, R. W. Bork, A. J. Valente, J. A. Berliner, D. C. Drinkwater, H. Laks, and A. M. Fogelman. 1991. Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotaetic protein-1 synthesis and is abolished by high density lipoprotein. J. Clin. Invest. 88:2039-2046.
7. Yoshimura, T., and F. J. Leonard. 1990. Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE. J. Immunol. 144:2377-2383.
8. Yoshimura, T., N. Yuhki, S. K. Moore, E. Appella, M. I. Lerman, and E. J. Leonard. 1989. Human monocyte chemoattractant protein-1 (MCP-1): full length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. FEBS (Fed. Eur. Biochem. Soc.) Lett. 244:487-493.
9. Wake, K. 1980. Perisinusoidal stellate cells (fat storing cells, interstitial cells, lipocytes): their related structure in and around the liver sinusoids and vitamin A storage cells in extrahepatic organs. Int. Rev. Cytol. 66:.303-353.
10. Blomhoff, R., and K. Wake. 1991. Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB (Fed. Amer. Soc. Exp. Biol.) J. 5:271-277.
11. Maher, J. J., and R. F. McGuire. 1990. Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J. Clin. Invest. 86:1641-1648.
12. Bissel, D. M. 1992. Lipocyte activation and hepatic fibrosis. Gastroenterology. 102:1803-1805.
13. De Leeuw, A. M., S. P. McCarty, A. Geerts, and D. L. Knook. 1984. Purified rat liver fat-storing cells in culture divide and contain collagen. Hepatology. 4:392-403.
14. Ramadori, G., H. Rieder, T. Knittel, H. P. Dienes, and K.-H. Meyer Zum Buschenfelde. 1987. Fat storing cells (ESC) of rat liver synthesize and secrete fibronectin. Comparison with hepatocytes. J. Hepatol. (Amst.) 4:190-197.
15. Friedman, S. L., F. J. Roll, J. Boyles, and D. M. Bissel. 1985. Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc. Natl. Acad. Sci. USA. 82:8681-8685.
16. Schafer, S., O. Zerbe, and A.M. Gressner. 1987. The synthesis of proteoglycans in fat storing cells of rat liver. Hepatology. 7:680-687.
17. Davis, B. H., B. M. Pratt, and J. A. Madri. 1987. Retinol and extracellular collagen matrices modulate hepatic Ito-cell collagen phenotype and cellular retinol binding levels. J. Biol. Chem. 262:10280-10286.
18. Geerts, A., R. Vrijsen, J. Rauterberg, A. Burt, P. Schellink, and E. Wisse. 1989. In vitro differentiation of fat storing cells parallels marked increase of collagen synthesis and secretion. J. Hepatol. (Amst.). 9:59-68.
19. Valente, A., M. M. Rozek, C. J. Schwartz, and D.T. Graves. 1991. Characterization of monocyte chemotactic protein-1 binding to human monocytes. Biochem. Biophys. Res Commun. 176:309-314.
20. Valente, A. J., S. R. Fowler, E. A. Sprague, J. L. Kelley, A. C. Suenram, and C. J. Schwartz. 1984. Initial characterization of a peripheral blood mononuclear cell chemoattractant derived from cultured arterial smooth muscle cells. Am. J. Pathol. 117:479-485.
21. Chomezynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.