Adenosine A1 Receptor Inhibition of Glutamate Exocytosis and Protein Kinase C‐Mediated Decoupling

Journal of Neurochemistry

Volumn 60, Issue 3, 1993, Pages 1081-1086

  Banie, Anne P ^a   Nicholls, David G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Adenosine; Calcium; Glutamate; Potassium; Protein kinase C; Synaptosome

Indexed keywords

4 AMINOPYRIDINE; 4BETA PHORBOL DIBUTYRATE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE DEAMINASE; ADENOSINE DERIVATIVE; CALCIUM CHANNEL; CALCIUM ION; CYCLOHEXYLADENOSINE; GLUTAMIC ACID; POTASSIUM CHANNEL; POTASSIUM CHLORIDE; POTASSIUM ION; PROTEIN KINASE C; 8 CYCLOPENTYLTHEOPHYLLINE; 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE; DRUG DERIVATIVE; FURA 2; GLUTAMIC ACID DERIVATIVE; N(6) CYCLOHEXYLADENOSINE; N(6)-CYCLOHEXYLADENOSINE; PURINE RECEPTOR; THEOPHYLLINE;

ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CALCIUM CELL LEVEL; CELL MEMBRANE POTENTIAL; EXOCYTOSIS; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BRAIN CORTEX; ENZYME ACTIVATION; METABOLISM; PHYSIOLOGY; SYNAPTOSOME;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

4-AMINOPYRIDINE; ADENOSINE; ANIMAL; CEREBRAL CORTEX; ENZYME ACTIVATION; EXOCYTOSIS; FURA-2; GLUTAMATES; GLUTAMIC ACID; GUINEA PIGS; POTASSIUM CHLORIDE; PROTEIN KINASE C; RECEPTORS, PURINERGIC; SUPPORT, NON-U.S. GOV'T; SYNAPTOSOMES; THEOPHYLLINE;

EID: 0027339856     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1993.tb03257.x     Document Type: Article

References (41)

1. 2‐Chloroadenosine‐sensitive calcium channels in synaptosomes: effects of barium
2. +‐induced calcium influx into rat brain synaptosomes: a possible mechanism for its prevention of kainate toxicity
3. 2‐Chloroadenosine attenuates kainic‐induced toxicity within the rat striaturn: relationship to release of glutamate and Ca influx
4. Synaptosomal calcium uptake unaltered by adenosine and 2‐chloroadenosine
5. An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes
6. Adenosine uptake and release by cortical synaptosomes
7. Adenosine modulation of potassium currents in preganglionic nerve terminals of avian ciliary ganglia
8. Ionic channels and their regulation by G protein subunits
9. G‐proteins and potassium currents in neurons
10. Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen
11. G protein modulation of calcium currents in neurons
12. An adenosine agonist inhibits and a cyclic AMP analog enhances the release of glutamate but not GABA from slices of rat dentate gyms
13. Pertussis toxin reverses adenosine inhibition of neuronal glutamate release
14. Adenosine modulation of sy nap tic responses in rat hippocampus: possible role of inhibition or activation of adenylate cyclase
15. Arachidonic acid metabolites do not mediate, modulation of neurotransmitter release by adenosine in rat hippocampus or striatum
16. B receptors in the hippocampus have different pharmacological properties
17. Presynaptic adenosine receptors
18. How does adenosine inhibit transmitter release?
19. A new generation of Ca indicators with greatly improved fluorescence properties
20. Protein kinase C phosphorylates the inhibitory guanine nucleotide binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase
21. 2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia
22. Cloning and expression of an Al adenosine receptor from rat brain
23. 2+
24. Studies on the ionic mechanism for the neuromodula‐tory actions of adenosine in the brain
25. The early time‐course of K‐stimulated Ca uptake in presynaptic nerve terminals isolated from rat brain
26. Calcium‐dependent and ‐independent release of glutamate from synaptosomes monitored by continuous fluorometry
27. The coupling of neurotransmitter receptors to ion channels in the brain
28. Adenosine and glutamate modulate each other's release from rat hippocampal synaptosomes
29. Adenosine antagonists increase spontaneous and evoked transmitter release from neuronal cells in culture
30. Adenosine and ATP decrease 45Ca uptake by synaptosomes stimulated by potassium
31. Role of G proteins in calcium channel modulation
32. Energy transduction in intact synaptosomes: influence of plasma‐membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ
33. Excitatory transmitter amino acid release from the isch‐emic rat cerebral cortex: effects of adenosine receptor agonists and antagonists
34. Adenosine as a neuromodulator
35. + conductance in central mammalian neurones under energy deprivation
36. Receptors for adenosine and adenine nucleo‐tides
37. Presynaptic calcium channels in rat cortical synaptosomes: fast kinetics of phasic calcium influx, channel inactiva‐tion, and relationship to nitrendipine receptors
38. 2+ and glutamate release
39. Adenosine agonists inhibit Ca uptake into synaptosomes
40. Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus
41. Ionic basis of inhibitory presynaptic modulation in rat cortical synaptosomes