Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats

Psychopharmacology

Volumn 111, Issue 4, 1993, Pages 427-434

  Ouagazzal, A ^a   Nieoullon, A ^a   Amalric, M ^a  

^a CNRS   (France)

Author keywords

D1 D2 dopamine receptors; Locomotor activity; MK 801; NMDA antagonist; Rat

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DEXAMPHETAMINE; DIZOCILPINE MALEATE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; RACLOPRIDE; SALICYLAMIDE DERIVATIVE; DIZOCILPINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 2 RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL; ARTICLE; CATALEPSY; DRUG EFFECT; IATROGENIC DISEASE; MALE; MOTOR ACTIVITY; PSYCHOLOGICAL ASPECT; RAT; RAT STRAIN; ANIMAL EXPERIMENT; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; HYPERACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; CATALEPSY; DEXTROAMPHETAMINE; DIZOCILPINE MALEATE; MALE; MOTOR ACTIVITY; RACLOPRIDE; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SALICYLAMIDES; SCH-23390; SUPPORT, NON-U.S. GOV'T;

EID: 0027337246     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/BF02253532     Document Type: Article

References (38)

1. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic and in situ hybridation techniques
2. The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice
3. Central sympathomimetic activity of (+)-5-methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic and apparent anxiolytic properties
4. Stereotypy and anti-cataleptic action of amphetamine after intracerebral injection
5. Effect of chronic treatment with dizocilpine (MK-801) on the behavioral response to dopamine receptor agonist in the rat
6. Antagonism of the hypermotility response induced by excitatory amino acids in the rats nucleus accumbens
7. Autoradiographic distribution of the D1 agonist3(H) SKF 38393 in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors
8. Glutamate: a neurotransmitter in mammalian brain
9. Activation of NMDA receptor induces dephosphorylation of DARPP-32 in rats striatal slices
10. Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats
11. NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus
12. Effects of dopamine on spontaneous and evoked activity of caudate neurons
13. Dopamine agonists potentiate antiakinetic effects of competitive NMDA-antagonists in monoamine-depleted mice
14. Topography and functional role of dopaminergic projections from the ventral mesencephalic tegmentum to the ventral pallidum
15. A simple and rapid method for assessing similarities among directly observable behavioral effects of drugs: PCP-like effects of 2-amino-5-phosphonovalerate in rats
16. MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
17. Mesocorticolimbic dopaminergic network: functional and regulatory roles
18. Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice
19. The N-methyl- d-aspartate receptor antagonist MK-801 induces increases in dopamine and serotonine metabolism in several brain regions of rats
20. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
21. Do endogenous excitatory amino acids influence striatal dopamine release?
22. Cellular interactions in the striatum involving neuronal systems using “classical” neurotransmitters: possible functional implications
23. Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum
24. In vivo demonstration of the enhancement of MK-801 by l-glutamate
25. Increased spontaneous activity and food intake produced in rats by removal prefrontal poles of the brain
26. Cortical modulation of striatal function
27. Intrastriatal injection of DL-2 amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine
28. Behavioural effects of N-methyl- d-aspartate in the anterodorsal striatum of the rat
29. A direct comparison of amphetamine-induced behaviours and regional brain release in the rat using intracerebral dialysis
30. Microanalysis of d-amphetamine into the nucleus accumbens and caudate putamen
31. Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotyped behavior and ataxia in rats
32. MK-801-induced stereotypy and its antagonism by neuroleptic drugs
33. The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor
34. Electrophysiological study of the effects of D1 and D2 dopamine antagonists on the interaction of converging inputs from the sensory-motor cortex and substantia nigra neurons in the rat
35. The effects of the non-competitive NMDA receptor antagonist MK-801 on DRL performance in rats
36. Immediate and long-lasting effects of MK-801 on motor activity, spatial navigation in a swimming pool and EEG in the rat
37. (3H) MK-801 labels a site on the N-methyl- d-aspartate receptor channel complex in rats brain membranes