Sa gene and blood pressure cosegregation using dahl salt-sensitive rats

American Journal of Hypertension

Volumn 6, Issue 4, 1993, Pages 330-334

  Harris, Eugenie L ^a   Dene, Howard ^a   Rapp, John P ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Alternate mRNA splicing; Dahl salt sensitive rat; Genetic hypertension; Restriction fragment length polymorphism

Indexed keywords

COMPLEMENTARY DNA; DNA; SODIUM CHLORIDE;

ALTERNATIVE RNA SPLICING; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEREDITARY HYPERTENSION; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; BLOOD PRESSURE; DRUG RESISTANCE; GENE; GENETICS; GENOME; MALE; MOLECULAR GENETICS; MOLECULAR PROBE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RAT STRAIN; SOUTHERN BLOTTING;

ANIMAL; BASE SEQUENCE; BLOOD PRESSURE; BLOTTING, SOUTHERN; DNA; DRUG RESISTANCE; GENES; GENOME; MALE; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RATS; RATS, MUTANT STRAINS; SODIUM CHLORIDE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027336532     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1093/ajh/6.4.330     Document Type: Article

References (15)

1. Iwai N, Inagami T: Isolation of preferentially expressed genes in the kidneys of hypertensive rats. Hypertension 1991;17:161-169.
2. Rapp J. P, Dene H: Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension 1985;7:340-349.
3. Heslop B. F, Phelan E. L: The GH and AS hypertensive rat strains. Lab Anim 1973;7:41-46.
4. Bunag R. D, Butterfield J: Tail-cuff blood pressure measurement without external preheating in awake rats. Hypertension 1982;4:498-903.
5. Deng Y, Rapp J. P: Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor genes using Dahl salt-sensitive rats. Nature Genetics 1992;1:267-272.
6. Blin N, Stafford DW: Isolation of high molecular weight DNA. Nucleic Acids Res 1976;3:2303-2308.
7. Southern E: Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975;98:503-517.
8. Martin C, Bresnick L, Juo R. R, Voyta JC, Bronstein I: Improved chemiluminescent DNA sequencing. BioTechniques 1991;11:110-113.
9. Liu Z. G, Schwartz L. M: An efficient method for blunt-end ligation of PCR products. Bio Techniques 1992,12:2830.
10. Iwai N, Inagami T: Identification of a candidate gene responsible for the high blood pressure of spontaneously hypertensive rats. J Hypertens 1992;10:1155-1157.
11. Iwai N, Kurtz T. W, Inagami T: Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat. Biochem Biophys Res Commun 1992;188:64-69.
12. Rapp J. P, Wang S-M, Dene H: Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats. Am J Hypertens 1990;3:391-396.
13. Cicila G. T, Rapp J. P, Block K. D, et al: Cosegregation of endothelin-3 and ll β -hydroxylase loci with blood pressure is dependent upon genetic background in inbred Dahl rats (abst). Hypertension 1992;20:444.
14. Cicila G. T, Rapp J. P, Wang J-M, et al: Linkage of 11β- hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nature Genetics (in press).
15. Seidel H. M, Pompliano D. L, Knowles J. R: Exons as microgenes? Science 1992;257:1489-1490.