Effect of activation on adhesion of flowing neutrophils to cultured endothelium: time course and inhibition by a calcium channel blocker (nitrendipine)

British Journal of Pharmacology

Volumn 110, Issue 4, 1993, Pages 1630-1634

  Perry, I ^a   Buttrum, S M ^a   Nash, G B ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

adhesion; calcium channel blockers; endothelium; Neutrophils; nitrendipine; rheology

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CD18 ANTIGEN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTEGRIN; MONOCLONAL ANTIBODY; NIFEDIPINE; NITRENDIPINE;

ADULT; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; UMBILICAL VEIN;

ADULT; ANTIGENS, CD; ANTIGENS, CD18; CELL ADHESION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMAN; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; NIFEDIPINE; NITRENDIPINE; SUPPORT, NON-U.S. GOV'T;

EID: 0027333268     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1993.tb14011.x     Document Type: Article

References (27)

1. Structure and function of the leukocyte adhesion molecules CD11/CD18
2. Neutrophil integrin assay for clinical studies
3. Platelet‐neutrophil interactions: possible relevance in the pathogenesis of thrombosis and inflammation
4. A simplified method for the culture of endothelial cells and analysis of adhesion of blood cells under conditions of flow
5. Activated polymorphonuclear leukocytes stimulate platelet function
6. Neutrophil endothelial interaction in critical illness
7. Nitrendipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of hypertension
8. Radial distribution of white cells in tube flow
9. Leukocyte‐endothelial interactions
10. Role of neutrophils in ischemia‐reperfusion‐induced microvascular injury
11. Microvascular haematocrit and red cell flow in resting and contracting striated muscle
12. Effect of venous shear stress on CD‐18 mediated neutrophil adhesion to cultured endothelium
13. Leukocytes roll on a selectin at physiological flow rates: distinction from and prerequisite for adhesion through integrins
14. Lectin‐like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo
15. The distribution of blood rheological parameters in the microcirculation of cat mesentery
16. Cytokine activated human neutrophil transmigration via mechanism involving both ELAM‐1 and ICAM‐1
17. Nifedipine affects neutrophil functions by a non‐calcium mediated mechanism
18. Leukocyte adhesion to endothelium in inflammation
19. fMLP induced neutrophil adhesion on endothelial cells can be inhibited by nitrendipine
20. Chemotactic factors regulate lectin adhesion molecule 1 (LECAM‐1) dependent neutrophil adhesion to cytokine stimulated endothelial cells in vitro
21. Cooperative interaction of LFA‐1 and Mac‐1 with ICAM‐1 in facilitating adherence and transendothelial migration of human neutrophils in vivo
22. Increased surface expression of CD11b/CD18 (Mac‐1) is not required for stimulated neutrophil adherence to cultured endothelium
23. A monoclonal antibody to the adherence‐promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorhrhagic shock and resuscitation in rabbits
24. Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries
25. Neutrophil adherence to human endothelium in vitro occurs by CD18 glycoprotein dependent and independent mechanisms
26. Endothelial cell interactions with granulocytes: tethering and signalling molecules
27. In vitro modulation of human neutrophil superoxide anion generation by various calcium channel antagonists used in ischaemia‐reperfusion resuscitation