-
1
-
-
0021998299
-
Nicotine-derived jV-nitrosamines and tobacco related cancer: Current status and future directions
-
Hoffmann, D. and Hecht, S.S. (1985) Nicotine-derived jV-nitrosamines and tobacco related cancer: current status and future directions. Cancer Res., 45, 935-944.
-
(1985)
Cancer Res.
, vol.45
, pp. 935-944
-
-
Hoffmann, D.1
Hecht, S.S.2
-
2
-
-
0023898409
-
Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke
-
Hecht, S.S. and Hoffmann, D. (1988) Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke. Carcinogenesis, 9, 875-884.
-
(1988)
Carcinogenesis
, vol.9
, pp. 875-884
-
-
Hecht, S.S.1
Hoffmann, D.2
-
3
-
-
0024262907
-
Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines
-
Rivenson A., Hoffmann, D., Prokopczyk, B., Amin, S. and Hecht, S.S. (1988) Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines. Cancer Res., 48, 6912-6917.
-
(1988)
Cancer Res.
, vol.48
, pp. 6912-6917
-
-
Rivenson, A.1
Hoffmann, D.2
Prokopczyk, B.3
Amin, S.4
Hecht, S.S.5
-
4
-
-
0025297169
-
-
Belinsky, S.A., Foley J.F., White, C.M., Andeisoa, M.W. and Maronpot, R.R. (1990) Dose-response relationship between O-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-l-(3-pyridyI)-l-butanone. Cancer Res., 50, 3772-3780.
-
(1990)
Dose-Response Relationship between O-Methylguanine Formation in Clara Cells and Induction of Pulmonary Neoplasia in the Rat by 4-(Methylnitrosamino)-L-(3-Pyridyi)-L-Butanone. Cancer Res.
, vol.50
, pp. 3772-3780
-
-
Belinsky, S.A.1
Foley, J.F.2
White, C.M.3
Eisoa, M.W.4
Maronpot, R.R.5
-
5
-
-
84969020911
-
-
Brugge, J., Curran, T., Harlow, E. and McCormick, F. (eds), Origins cf Human Cancer: A Comprehensive Review, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hecht, S.S. and Hof6nann, D. (1991) 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone, a nicotine-derived tobacco-specific nitrosamine, and cancer of the lung and pancreas in humans. In Brugge, J., Curran, T., Harlow, E. and McCormick, F. (eds), Origins cf Human Cancer: A Comprehensive Review, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 745-755.
-
(1991)
4-(Methylnitrosamino)-L-(3-Pyridyl)-L-Butanone, a Nicotine-Derived Tobacco-Specific Nitrosamine, and Cancer of the Lung and Pancreas in Humans
, pp. 745-755
-
-
Hecht, S.S.1
Hof6nann, D.2
-
6
-
-
0027522682
-
Metabolites of the tobacco-specific nitrosamine 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone in smoker’s urine
-
Carmella, S.G., Akerkar, S. and Hecht, S.S. (1993) Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone in smoker’s urine. Cancer Res., 53, 721-724.
-
(1993)
Cancer Res.
, vol.53
, pp. 721-724
-
-
Carmella, S.G.1
Akerkar, S.2
Hecht, S.S.3
-
7
-
-
0025160968
-
Mass spectrometric analysis of tobacco-specific nitrosamine hemoglobin adducts in snuff dippers, smokers, and non-smokers
-
Carmella, S.G., Kagan, S.S., Kagan, M., Foiles, P.G., Palladino, G., Quart, A.M., Quart, E. and Hecht, S.S. (1990) Mass spectrometric analysis of tobacco-specific nitrosamine hemoglobin adducts in snuff dippers, smokers, and non-smokers. Cancer Res., 50, 5438-5445.
-
(1990)
Cancer Res.
, vol.50
, pp. 5438-5445
-
-
Carmella, S.G.1
Kagan, S.S.2
Kagan, M.3
Foiles, P.G.4
Palladino, G.5
Quart, A.M.6
Quart, E.7
Hecht, S.S.8
-
8
-
-
0025731616
-
Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers
-
Foiles, P.G., Akerkar, S.A., Carmella, S.G., Kagan, M., Stoner, G.D., Resau, J.H. and Hecht, S.S. (1991) Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers. Chem. Res. Toxicol, 4, 364-368.
-
(1991)
Chem. Res. Toxicol
, vol.4
, pp. 364-368
-
-
Foiles, P.G.1
Akerkar, S.A.2
Carmella, S.G.3
Kagan, M.4
Stoner, G.D.5
Resau, J.H.6
Hecht, S.S.7
-
9
-
-
0027319674
-
Smoking-related DNA adducts: 32P-postlabeling analysis of 7-methylguanine in human bronchial and lymphocyte DNA
-
Mustonen, R., Schoket, B. and Hemminlri, K. (1993) Smoking-related DNA adducts: 32P-postlabeling analysis of 7-methylguanine in human bronchial and lymphocyte DNA. Carcinogenesis, 14, 151-154.
-
(1993)
Carcinogenesis
, vol.14
, pp. 151-154
-
-
Mustonen, R.1
Schoket, B.2
Hemminlri, K.3
-
10
-
-
0025925258
-
06-Methylguanine is a critical determinant of 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone tumorigenesis in A/J mouse lung
-
Peterson, L.A. and Hecht, S.S. (1991) 06-Methylguanine is a critical determinant of 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone tumorigenesis in A/J mouse lung. Cancer Res., 51, 5557-5564.
-
(1991)
Cancer Res.
, vol.51
, pp. 5557-5564
-
-
Peterson, L.A.1
Hecht, S.S.2
-
11
-
-
0024437222
-
The relationship between the formation of promutagenic adducts and the activation of the K-ras proto-oncogene in lung tumors from A/J mice treated with nitrosamines
-
Belinksy, S.A., Devereux, T.R., Maronpot, R.R., Stoner, G.D. and Anderson, M.W. (1989) The relationship between the formation of promutagenic adducts and the activation of the K-ras proto-oncogene in lung tumors from A/J mice treated with nitrosamines. Cancer Res., 49, 5305-5311.
-
(1989)
Cancer Res.
, vol.49
, pp. 5305-5311
-
-
Belinksy, S.A.1
Devereux, T.R.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
12
-
-
0026495439
-
Mutational analysis of a dominant oncogene (C-Ki-rar-2) and a tumor suppressor gene (p53) in hamster lung tumorigenesis. Mol
-
Oreffo, V.I.C., Lin, H.-W., Gumerlock, P.H., Kraegel, S.A. and Witschi, H. (1992) Mutational analysis of a dominant oncogene (c-Ki-rar-2) and a tumor suppressor gene (p53) in hamster lung tumorigenesis. Mol. Carcinogenesis, 6, 199-202.
-
(1992)
Carcinogenesis
, vol.6
, pp. 199-202
-
-
Oreffo, V.I.C.1
Lin, H.-W.2
Gumerlock, P.H.3
Kraegel, S.A.4
Witschi, H.5
-
13
-
-
0020954912
-
Effects of a-deuterium substitution on the mutagenicity of 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone (NNK)
-
Hecht, S.S., Lin, D. and Castonguay, A. (1983) Effects of a-deuterium substitution on the mutagenicity of 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone (NNK). Carcinogenesis, 4, 305-310.
-
(1983)
Carcinogenesis
, vol.4
, pp. 305-310
-
-
Hecht, S.S.1
Lin, D.2
Castonguay, A.3
-
14
-
-
0025050762
-
Solvolysis of model compounds for a-hydroxylation of N'-nitrosonornicotine and 4-(Methyhritrosamino)-l-(3-pyridyI)-l-butanone: Evidence for a cyclic oxonium ion intermediate in the alkylation of nucleophiles
-
Spratt, T.E., Peterson, L.A., Confer, W.L. and Hecht, S.S. (1990) Solvolysis of model compounds for a-hydroxylation of N'-nitrosonornicotine and 4-(methyhritrosamino)-l-(3-pyridyI)-l-butanone: evidence for a cyclic oxonium ion intermediate in the alkylation of nucleophiles. Chem. Res. Toxicol, 3, 350-356.
-
(1990)
Chem. Res. Toxicol
, vol.3
, pp. 350-356
-
-
Spratt, T.E.1
Peterson, L.A.2
Confer, W.L.3
Hecht, S.S.4
-
15
-
-
0020663028
-
Comparative carcinogenicity in A/J mice and metabolism by cultured mouse peripheral lung of N'-nitrosonor-nicotine, 4-(Methylmtrosamino)-l-(3-pyridyl)-l-butanone and their analogues
-
Castonguay, A., Lin, D., Stoner, G.D., Radok, P., Furuya, K., Hecht, S.S., Schut, H.A.J. and Klaunig J.E. (1983) Comparative carcinogenicity in A/J mice and metabolism by cultured mouse peripheral lung of N'-nitrosonor-nicotine, 4-(methylmtrosamino)-l-(3-pyridyl)-l-butanone and their analogues. Cancer Res., 43, 1223-1229.
-
(1983)
Cancer Res.
, vol.43
, pp. 1223-1229
-
-
Castonguay, A.1
Lin, D.2
Stoner, G.D.3
Radok, P.4
Furuya, K.5
Hecht, S.S.6
Schut, H.A.J.7
Klaunig, J.E.8
-
16
-
-
0025854453
-
Dietary N-3 fatty acids do not affect induction of Ha-raj mutations in mammary glands of NMU treated rats
-
Ronai, Z., Lau, Y. and Cohen, L.A. (1991) Dietary N-3 fatty acids do not affect induction of Ha-raj mutations in mammary glands of NMU treated rats. Mol Carcinogenesis, 4, 120-128.
-
(1991)
Mol Carcinogenesis
, vol.4
, pp. 120-128
-
-
Ronai, Z.1
Lau, Y.2
Cohen, L.A.3
-
17
-
-
0024312892
-
Rapid detection of ras oncogenes in human tumors. Applications to colon, esophageal and gastric cancer
-
Jiang, W., Kahn, S.M., Guillem J.G., Lu, S. and Weinstein, I.B. (1989) Rapid detection of ras oncogenes in human tumors. Applications to colon, esophageal and gastric cancer. Oncogene, 4, 923-928.
-
(1989)
Oncogene
, vol.4
, pp. 923-928
-
-
Jiang, W.1
Kahn, S.M.2
Guillem, J.G.3
Lu, S.4
Weinstein, I.B.5
-
18
-
-
0007142725
-
Activation of the Ki-rar protooncogene in spontaneously occurring and chemically induced lung tumors in the strain A mouse
-
You, M., Candrian, U., Maronpot, R.R., Stoner, G.D. and Anderson, M.W. (1989) Activation of the Ki-rar protooncogene in spontaneously occurring and chemically induced lung tumors in the strain A mouse. Proc. Natl Acad. Sd. USA, 86, 3070-3074.
-
(1989)
Proc. Natl Acad. Sd. USA
, vol.86
, pp. 3070-3074
-
-
You, M.1
Candrian, U.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
19
-
-
0021505055
-
In vivo mutagenesis by 06-methylguanine built into a unique site in a viral genome
-
Loediler, E.L., Green, C.L. and Essigmann, J.M. (1984) In vivo mutagenesis by 06-methylguanine built into a unique site in a viral genome. Proc. Natl. Acad. Sci. USA, 81, 6271-6275.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 6271-6275
-
-
Loediler, E.L.1
Green, C.L.2
Essigmann, J.M.3
-
20
-
-
0025831694
-
Site-specific mutagenesis: Restrospective and prospective
-
Singer, B. and Fssigmann, J.M. (1991) Site-specific mutagenesis: restrospective and prospective. Carcinogenesis, 12, 949-955.
-
(1991)
Carcinogenesis
, vol.12
, pp. 949-955
-
-
Singer, B.1
Fssigmann, J.M.2
-
21
-
-
0025307212
-
Effects of deuterium substitution on the tumorigenicity of 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone and 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanol in A/J mice
-
Hecht, S.S., Jordan, K.G., Choi, C.-I. and Trushin, N. (1990) Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone and 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanol in A/J mice. Carcinogenesis, 11, 1017-1020.
-
(1990)
Carcinogenesis
, vol.11
, pp. 1017-1020
-
-
Hecht, S.S.1
Jordan, K.G.2
Choi, C.-I.3
Trushin, N.4
-
22
-
-
0027324849
-
Pyridyloxobutyl DNA adducts inhibit the repair of 06-methylguanine
-
Peterson, L.A., Liu, X.-K. and Hecht, S.S. (1993) Pyridyloxobutyl DNA adducts inhibit the repair of 06-methylguanine. Cancer Res., 53, 2780-2785.
-
(1993)
Cancer Res.
, vol.53
, pp. 2780-2785
-
-
Peterson, L.A.1
Liu, X.-K.2
Hecht, S.S.3
-
23
-
-
0026009488
-
In vivo and in vitro persistence of pyridyloxobutyl DNA adducts from 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone
-
Peterson, L.A., Mathew, R., Murphy, S.E., Trushin, N. and Hecht, S.S. (1991) In vivo and in vitro persistence of pyridyloxobutyl DNA adducts from 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone. Carcinogenesis, 12, 2069-2072.
-
(1991)
Carcinogenesis
, vol.12
, pp. 2069-2072
-
-
Peterson, L.A.1
Mathew, R.2
Murphy, S.E.3
Trushin, N.4
Hecht, S.S.5
-
24
-
-
0024470902
-
Analysis of N2-(Pyridyloxobutyl)deoxyguanosine adducts in DNA of tissues exposed to tritium-labeled 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone and N'-nitrosonomicodne
-
Spratt, T.E., Trushin, N., Lin, D. and Hecht, S.S. (1989) Analysis of N2-(pyridyloxobutyl)deoxyguanosine adducts in DNA of tissues exposed to tritium-labeled 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone and N'-nitrosonomicodne. Chem. Res. Toxicol, 2, 169-173.
-
(1989)
Chem. Res. Toxicol
, vol.2
, pp. 169-173
-
-
Spratt, T.E.1
Trushin, N.2
Lin, D.3
Hecht, S.S.4
-
25
-
-
0025965491
-
Role of Clara cells and type n cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine. Exp
-
Belinksy, S.A., Devereux, T.R., White, C.M., Foley, J.F., Maronpot, R.R. and Anderson, M.W. (1991) Role of Clara cells and type n cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine. Exp. Lung Res., 17, 263-278.
-
(1991)
Lung Res.
, vol.17
, pp. 263-278
-
-
Belinksy, S.A.1
Devereux, T.R.2
White, C.M.3
Foley, J.F.4
Maronpot, R.R.5
Anderson, M.W.6
-
26
-
-
0023292873
-
Effects of a-deuterium substitution on the tumorigenicity of 4-(Methylnitrosamino)-l-(3-pyridyl)-l-butanone in F344 rats
-
Hecht, S.S., Lin, D., Castonguay, A. and Rivenson, A. (1987) Effects of a-deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone in F344 rats. Carcinogenesis, 8, 291-294.
-
(1987)
Carcinogenesis
, vol.8
, pp. 291-294
-
-
Hecht, S.S.1
Lin, D.2
Castonguay, A.3
Rivenson, A.4
-
28
-
-
0024469980
-
Alkyl and aryl carcinogen adducts detected in human peripheral lung
-
Wilson, V.L., Weston, A., Manchester, D.K., Trivers, G.E., Roberts, D.W., Kadlubar, F.F., Wild, C.P., Montesano, R., Wiley, J.C. and Mann, D.L. and Harris, C.C. (1989) Alkyl and aryl carcinogen adducts detected in human peripheral lung. Carcinogenesis, 10, 2149-2153.
-
(1989)
Carcinogenesis
, vol.10
, pp. 2149-2153
-
-
Wilson, V.L.1
Weston, A.2
Manchester, D.K.3
Trivers, G.E.4
Roberts, D.W.5
Kadlubar, F.F.6
Wild, C.P.7
Montesano, R.8
Wiley, J.C.9
Mann, D.L.10
Harris, C.C.11
-
29
-
-
0026794922
-
Mutagenesis by (+)-o«!-B[a]P-N2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods
-
Mackay, W., Benasutti, M., Drouin, E. and Loechler, E.L. (1992) Mutagenesis by (+)-o«!-B[a]P-N2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods. Carcinogenesis, 13, 1415-1425.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1415-1425
-
-
Mackay, W.1
Benasutti, M.2
Drouin, E.3
Loechler, E.L.4
-
30
-
-
0026502120
-
-
Bigger, C.A.H., St John, J., Yagi, H., Jerina, D.M. and Dipple, A. (1992) Mutagenic specificities of four stereoisomeric benzo[c]phenanthrene dihydrodiol epoxides. Proc. Natl Acad. Sci. USA, 89, 368-372.
-
(1992)
Mutagenic Specificities of Four Stereoisomeric Benzo[C]Phenanthrene Dihydrodiol Epoxides. Proc. Natl Acad. Sci. USA
, vol.89
, pp. 368-372
-
-
Bigger, C.A.H.1
St John, J.2
Yagi, H.3
Jerina, D.M.4
Dipple, A.5
-
31
-
-
10244233809
-
Molecular mechanisms of chemical mutagenesis
-
Grollman A.P. (1989) Molecular mechanisms of chemical mutagenesis. Proc. Am. Assoc. Cancer Res., 30, 682.
-
(1989)
Proc. Am. Assoc. Cancer Res.
, vol.30
, pp. 682
-
-
Grollman, A.P.1
-
32
-
-
0024455022
-
Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the bepatocarrinogen 2-nitropropane
-
Fiala, E.S., Conaway, C.C. and Mathis, J.E. (1989) Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the bepatocarrinogen 2-nitropropane. Cancer Res., 49, 5518-5522.
-
(1989)
Cancer Res.
, vol.49
, pp. 5518-5522
-
-
Fiala, E.S.1
Conaway, C.C.2
Mathis, J.E.3
|