Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor

Cell

Volumn 75, Issue 4, 1993, Pages 681-692

  Franzén, Petra ^a   ten Dijke, Peter ^a   Ichijo, Hidenori ^a   Yamashita, Hidetoshi ^a   Schulz, Peter ^a   Heldin, Carl Henrik ^a   Miyazono, Kohei ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

SUIDAE; ANIMALIA; SUS SCROFA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SWINE;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CELLS, CULTURED; CLONING, MOLECULAR; COMPARATIVE STUDY; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMAN; IN VITRO; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; RESTRICTION MAPPING; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T; SWINE; TISSUE DISTRIBUTION; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0027332995     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(93)90489-D     Document Type: Article

References (65)

1. Transforming growth factor betas in mammalian embryogenesis
2. Transforming growth factor-β in human platelets: identification of a major storage site, purification, and characterization
3. Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
4. Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors
5. Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma
6. Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor
7. Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells
8. Isoform-specific transforming growth factor-β binding proteins with membrane attachments sensitive to phosphatidylinositol-specific phospholipase C
9. The transforming growth factor-β receptor type III is a membrane proteoglycan: domain structure of the receptor
10. 3·pituitary cells that recognizes transforming growth factor-β, activin, and inhibin
11. Distinct transforming growth factor-β (TGF-β) receptor subsets as determinants of cellular responsiveness to three TGF-β isoforms
12. Endoglin is a component of the transforming growth factor-β receptor system in human endothelial cells
13. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
14. Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
15. Characterization of a membrane receptor for transforming growth factor-β in normal rat kidney fibroblasts
16. Inhibition of growth by transforming growth factor-β following fusion of two nonresponsive human carcinoma cell lines: implication of the type II receptor in growth inhibitory responses
17. daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
18. Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line
19. Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells
20. Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function
21. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains
22. Fast and sensitive multiple sequence alignments on a microcomputer
23. Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells
24. Purification of transforming growth factor-β1 binding proteins from porcine uterus membranes
25. Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains
26. Growth inhibition by transforming growth factor β (TGF-β) type I is restored in TGF-β-resistant hepatoma cells after expression of TGF-β receptor type II cDNA
27. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
28. A simple method for displaying the hydropathic character of a protein
29. Concomitant loss of transforming growth factor (TGF)-β receptor types I and II in TGF-β-resistant cell mutants implicates both receptor types in signal transduction
30. Responsiveness to transforming growth factor-β (TGF-β) restored by genetic complementation between cells defective in TGF-β receptors I and II
31. Control of JunB and extracellular matrix protein expression by transforming growth factor-β1 is independent of SV40 T antigen-sensitive growth inhibitory events
32. Generation of cDNA probes directed by amino acid sequence: cloning of urate oxidase
33. Receptors for the TGF-β superfamily: multiple polypeptides and serine/threonine kinases
34. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
35. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system
36. Betaglycan presents ligand to the TGFβ signaling receptor
37. The DVR gene family in embryonic development
38. Receptors for the TGF-β family
39. TGF-β receptors and TGF-β binding proteoglycans recent progress in identifying their functional properties
40. Expression cloning of an activin receptor, a predicted transmembrane serine kinase
41. Cloning of a second type of activin receptor and functional characterization in Xenopus embryos
42. A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, or bone morphogenic factor
43. Cytokine receptors and signal transduction
44. Latent high molecular weight complex of transforming growth factor β1: purification from human platelets and structural characterization
45. Receptors for transforming growth factor-β
46. Molecular cloning and characterization of the human and porcine transforming growth factor-β type III receptors
47. Type-β transforming growth factor is a growth stimulator and a growth inhibitor
48. TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights
49. Subunit promiscuity among hemopoietic growth factor receptors
50. Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells
51. The transforming growth factor-βs
52. DNA sequencing with chain-terminating inhibitors
53. Binding of transforming growth factor-β to cell surface proteins varies with cell type
54. Activin receptor-like kinases: a novel subclass of cell surface receptors with predicted serine/threonine kinase activity
55. Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of human kidney cDNA
56. The inhibin/activin family of hormones and growth factors
57. A new method for predicting signal sequence cleavage sites
58. Expression cloning and characterization of the TGF-β type III receptor
59. Charge clusters and the orientation of membrane proteins
60. B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase
61. Transformation of mammalian cells with genes from procaryotes and eucaryotes
62. Novel regulators of bone formation: molecular clones and activities
63. TGFβ signals through a heteromeric protein kinase receptor complex
64. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19