Pilot evaluation of influenza virus vaccine (IVV) combined with adjuvant

Vaccine

Volumn 11, Issue 9, 1993, Pages 909-913

  Keitel, W ^a   Couch, R ^a   Bond, N ^a   Adair, S ^b   Van Nest, G ^b   Dekker, C ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

adjuvant; Influenza virus vaccine; muramyl tripeptide phosphatidylethanolamine; safety

Indexed keywords

IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; MURAMYL TRIPEPTIDE; PHOSPHATIDYLETHANOLAMINE;

ADULT; ARTICLE; CHILL; CONTROLLED STUDY; DRUG SAFETY; ERYTHEMA; HUMAN; HUMAN EXPERIMENT; IMMUNIZATION; INFLUENZA; INJECTION PAIN; INTRAMUSCULAR DRUG ADMINISTRATION; LYMPHADENOPATHY; NORMAL HUMAN; VERTIGO;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; ADULT; ANIMAL; ANTIBODIES, VIRAL; DIZZINESS; EMULSIONS; ENDOTOXINS; ERYTHEMA; FATIGUE; FEVER; HUMAN; INFLUENZA A VIRUS, HUMAN; INFLUENZA B VIRUS; INFLUENZA VACCINE; INJECTIONS, INTRAMUSCULAR; MALE; NAUSEA; NEUTRALIZATION TESTS; PAIN; PHOSPHATIDYLETHANOLAMINES; PILOT PROJECTS; RABBITS; SAFETY; SUPPORT, U.S. GOV'T, P.H.S.; VACCINES, INACTIVATED;

EID: 0027326731     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0264-410X(93)90376-9     Document Type: Article

References (19)

1. Prevention and control of influenza
2. Influenza vaccination of elderly persons; reduction in pneumonia and influenza hospitalization and deaths
3. Response of elderly subjects to monovalent A/USSR/77 (H1N1) and trivalent A/USSR/77 (H1N1) and trivalent A/USSR/77 (H1N1) A/Texas/77 (H3N2)-B/HongKong/72 vaccines
4. Present and future of inactivated virus vaccines
5. The clinical application of adjuvant 65
6. Studies on vaccination of infants against influenza with influenza haemagglutinin (38069)
7. Biological activities of muramyl dipeptide, a synthetic glycopeptide analogous to bacterial immunoregulating agents
8. Influenza viruses
9. Microneutralization test for influenza A and B and parainfluenza 1 and 2 viruses that uses continuous cell lines and fresh serum enhancement
10. Safety and immunogenicity of a genetically engineered human immunodeficiency virus vaccine
11. Phase I trial of liposomal muramyl tripeptide phosphatidylethanolamine in cancer patients
12. Initial clinical trial of the macrophage activator muramyl tripeptide-phosphatidylethanolamine encapsulated in liposomes in patients with advanced cancer
13. A note on the failure of CGP 19835 A (MTP-PE) to influence the course of influenza A2 infection in human volunteers
14. Interleukin-6 induction by a muramyltripeptide derivative in cancer patients
15. Enhancement of endotoxic shock by N-acetylmuramyl-l-alanyl-(l-seryl)-d-isoglutamine (muramyl dipeptide)
16. Priming effect of orally administered muramyl dipeptide on induction of endogenous tumor necrosis factor
17. Phase I study of recombinant tumor necrosis factor in cancer patients
18. Clinical pharmacology of recombinant human tumor necrosis factor patients with advanced cancer