Benzodiazepine peptidomimetics: Potent inhibitors of Ras farnesylation in animal cells

Science

Volumn 260, Issue 5116, 1993, Pages 1937-1942

  James, Guy L ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a   Rawson, Thomas E ^b   Somers, Todd C ^b   McDowell, Robert S ^b   Crowley, Craig W ^b   Lucas, Brian K ^b   Levinson, Arthur D ^b   Marsters Jr , James C ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZODIAZEPINE DERIVATIVE; RAS PROTEIN;

ARTICLE; COLON; FARNESYL TRANSFERASE; LUNG; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN MODIFICATION; TUMOR GROWTH;

AMINO ACID SEQUENCE; ANIMAL; ANTINEOPLASTIC AGENTS; BENZODIAZEPINONES; CELL DIVISION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CHO CELLS; DRUG DESIGN; HAMSTERS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; ONCOGENE PROTEINS; PROTEIN ISOPRENYLATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFERASES;

ANIMALIA;

EID: 0027323459     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.8316834     Document Type: Article

References (0)