Induction of heat shock hsp70 mRNA and HSP70 kDa protein in neurons in the 'penumbra' following focal cerebral ischemia in the rat

Brain Research

Volumn 619, Issue 1-2, 1993, Pages 334-338

  Kinouchi, Hiroyuki ^a   Sharp, Frank R ^a,b   Koistinaho, Jari ^a,b   Hicks, Katy ^a,b   Kamii, Hideyuki ^a   Chan, Pak H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Heat shock protein; Immunocytochemistry; In situ hybridization; Ischemia; Middle cerebral artery occlusion; mRNA

Indexed keywords

HEAT SHOCK PROTEIN; RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; AUTORADIOGRAPHY; BRAIN; CEREBRAL INFARCTION; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; ISCHEMIC ATTACK, TRANSIENT; MALE; NEURONS; ORGAN SPECIFICITY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SULFUR RADIOISOTOPES; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0027320667     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(93)91630-B     Document Type: Article

References (13)

1. Induction of HSP70 mRNA after transient ischemia in gerbil brain
2. Thresholds in cerebral ischemia: the ischemic penumbra
3. Heat shock proteins as markers of neuronal injury
4. Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat
5. Distribution of the 72-kd heat shock protein as a function of transient focal cerebral ischemia in rats
6. Expression of heat shock protein 70 and heat shock cognate 70 messenger RNAs in rat cortex and cerebellum after heat shock or amphetamine treatment
7. Localization of 70 kDa stress protein mRNA induction in gerbil brain after ischemia
8. Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction
9. Sequential metabolic changes in rat brain following middle cerebral artery occlusion: a 2-deoxyglucose study
10. N-Methyl-d-aspartate antagonist reduces stroke size and regional glucose metabolism
11. N-methyl-d-aspartate antagonist reduces stroke size and regional glucose metabolism
12. Localization of 70kD stress protein induction in gerbil brain after ischemia
13. Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain