A Reexamination of the Folding Mechanism of Dihydrofolate Reductase from Escherichia coli: Verification and Refinement of a Four-Channel Model

Biochemistry

Volumn 32, Issue 14, 1993, Pages 3783-3789

  Jennings, Patricia A ^a,b   Finn, Bryan E ^a,c   Jones, Bryan E ^a   Matthews, C Robert ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE;

ARTICLE; CHEMICAL STRUCTURE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME STRUCTURE; ESCHERICHIA COLI; ISOMERISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; THERMODYNAMICS;

BINDING SITES; ESCHERICHIA COLI; FOLIC ACID ANTAGONISTS; KINETICS; METHOTREXATE; PROTEIN FOLDING; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY; SUPPORT, U.S. GOV'T, NON-P.H.S.; TETRAHYDROFOLATE DEHYDROGENASE; UREA;

EID: 0027315969     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00065a034     Document Type: Article

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