Distribution of GBM heparan sulfate proteoglycan core protein and side chains in human glomerular diseases

Kidney International

Volumn 43, Issue 2, 1993, Pages 454-463

  Van Den Born, Jacob ^a   Van Den Heuvel, Lambert P W J ^b   Bakker, Marinka A H ^b   Veerkamp, Jacques H ^b   Assmann, Karel J M ^b   Weening, Jan J ^b   Berden, Jo H M ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; HEPARAN SULFATE; MONOCLONAL ANTIBODY;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST; GLOMERULOPATHY; GLOMERULUS FILTRATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY DISEASE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANTIBODIES, MONOCLONAL; BASEMENT MEMBRANE; FLUORESCENT ANTIBODY TECHNIQUE; HEPARAN SULFATE PROTEOGLYCAN; HEPARITIN SULFATE; HUMAN; KIDNEY DISEASES; KIDNEY GLOMERULUS; PROTEOGLYCANS; SUPPORT, NON-U.S. GOV'T; TISSUE DISTRIBUTION;

EID: 0027312478     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1993.67     Document Type: Article

References (81)

1. DWORKIN LD, BRENNER BM: Biophysical basis of glomerular filtration, in The Kidney; Physiology and Pathophysiology, edited by SELDIN DW, GIEBISCH G, New York, Raven Press, Ltd., 1992, p. 979
2. KANWAR YS, LIU ZZ, KASHIHARA N, WALLNER EI: Current status of the structural and functional basis of glomerular filtration and proteinuria. Semin Nephrol 11:390-413, 1991
3. FARQUHAR MG: The glomerular basement membrane. A selective macromolecular filter, in Cell Biology of Extracellular Matrix, edited by HAY ED, New York, Plenum Press, 1991, p. 365
4. ROSENZWEIG LJ, KANWAR YS: Removal of sulfated (heparan sulfate) or nonsulfated (hyaluronic acid) glycosaminoglycans results in increased permeability of the glomerular basement membrane to 125-I-bovine serum albumine. Lab Invest 47:177-184, 1982
5. KANWAR YS, LINKER A, FARQUHAR MG: Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J Cell Biol 86:680-693, 1980
6. KANWAR YS, FARQUHAR MG: Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes. Proc Natl Acad Sci USA 76:4493-4497, 1979
7. KANWAR YS, FARQUHAR MG: Presence of heparan sulfate in the glomerular basement membrane. Proc Natl Acad Sci USA 76:1303-1307, 1979
8. VEHASKARI VM, ROOT ER, GERMUTH FG, ROBSON AM: Glomerular charge and urinary protein excretion. Effects of systemic and intrarenal polycation infusion in the rat. Kidney Int 22:127-135, 1982
9. HUNSICKER LG, SHEARER TP, SHAFFER SJ: Acute reversible proteinuria induced by infusion of the polycation hexadimethrine. Kidney Int 20:7-17, 1981
10. KELLEY VE, CAVALLO T: Glomerular permeability, transfer of native ferritin in glomeruli with decreased anionic sites. Lab Invest 39:547-553, 1978
11. ASSEL E, NEUMANN K-H, SCHUREK H-J, SONNENBURG C, STOLTE H: Glomerular albumin leakage and morphology after neutralization of polyanions; I. Albumin clearance and sieving coefficient in the isolated perfused rat kidney. Renal Physiol (Basel) 7:357-364, 1984
12. SONNENBURG-HATZOPOULOS C, ASSEL E, SCHUREK HJ, STOLTE H: Glomerular albumin leakage and morphology after neutralization of polyanions; II. Discrepancy of protamine induced albuminuria and fine structure of the glomerular filtration barrier. J Submicrosc Cytol 16:741-751, 1984
13. VAN DEN BORN J, VAN DEN HEUVEL LPWJ, BARKER MAH, VEERKAMP JH, ASSMANN KJM, BERDEN JHM: A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats. Kidney Int 41:115-123, 1992
14. COTRAN RS, RENNKE HG: Anionic sites and the mechanisms of proteinuria. N Engl J Med 309:1050-1052, 1983
15. CAMUSSI G, TETTA C, SEGOLONI G, CODA R, VERCELLONE A: Localization of neutrophil cationic proteins and loss of anionic charges in glomeruli of patients with systemic lupus erythematosus glomerulonephritis. Clin Immunol Immunopathol 24:299-314, 1982
16. KELLEY VE, CAVALLO T: Glomerular permeability. Focal loss of anionic sites in glomeruli of proteinuric mice with lupus nephritis. Lab Invest 42:59-64, 1980
17. MELNICK GF, LADOULIS CT, CAVALLO T: Decreased anionic groups and increased permeability precedes deposition of immune complexes in the glomerular capillary wall. Am J Pathol 105:114-120, 1981
18. MAHAN JD, SISSON-ROSS S, VERNIER RL: Glomerular basement membrane anionic charge site changes in aminonucleoside nephrosis. Am J Pathol 125:393-401, 1986
19. BLAU EB, HAAS JE: Glomerular sialic acid and proteinuria in human renal disease. Lab Invest 28:477-481, 1973
20. SCHNEEBERGER EE, STRAVRAKIS G, MCCARTHY K: Alteration in glomerular anionic sites in autologous immune complex nephritis. Lab Invest 49:445-452, 1983
21. OKADA K, KAWAKAMI K, MIYAO M, OITE T: Ultrastructural alterations of glomerular anionic sites in idiopathic membranous glomerulonephritis. Clin Nephrol 26:7-14, 1986
22. SASAKI M, BATSFORD S, THAISS F, OITE T, VOGT A: Ultrastructural studies in passive in situ immune complex glomerulonephritis. A rat model for membranous glomerulonephritis. Virchows Arch B 58:173-180, 1989
23. DUAN H-J, NAKAZAWA K, ISHIGAME H, ITOH N, SHIGEMATSU H: Masking of anionic sites by deposits in lamina rara externa in immune complex nephritis in rats. Virchows Arch B 60:165-171, 1991
24. SUZUKI Y, MAESAWA A, MATSUI K, OITE T, KODA Y, ARAKAWA M: Alteration of glomerular anionic sites by the development of subepithelial deposits in experimental glomerulonephritis in the rat. Virchows Arch B 44:209-222, 1983
25. VERNIER RL, KLEIN DJ, SISSON SP, MAHAN JD, OEGEMA TR, BROWN DM: Heparan sulfate-rich anionic sites in the human glomerular basement membrane; decreased concentration in congenital nephrotic syndrome. N Engl J Med 309:1001-1009, 1983
26. OKADA K, KAWAKAMI K, YANO I, FUNAI M, KAGAMI S, KURODA Y, OITE T: Ultrastructural alterations of glomerular anionic sites in IgA nephropathy. Clin Nephrol 31:96-102, 1989
27. TOMINO Y, YAGAME M, EGUCHI K, MIYAZAKI M, NOMOTO Y, SAKAI H, SHIRATO I, ITO K: Detection of anionic sites and IgA deposits in the glomerular capillary walls from patients with IgA nephropathy. J Clin Lab Anal 3:101-107, 1989
28. ROHRBACH R: Reduced content and abnormal distribution of anionic sites (acid proteoglycans) in the diabetic glomerular basement membrane. Virchows Arch B 51:127-135, 1986
29. CHAKRABARTI S, MA N, SIMA AAF: Reduced number of anionic sites is associated with glomerular basement membrane thickening in the diabetic BB-rat. Diabelologia 32:826-328, 1989
30. VERNIER RL, STEFFES MW, SISSON-ROSS S, MAUER M: Heparan sulfate proteoglycan in the glomerular basement membrane in type I diabetes mellitus. Kidney Int 41:1070-1080, 1992
31. GROGGEL GC, STEVENSON J, HOVINGH P, LINKER A, BORDER WA: Changes in heparan sulfate correlate with increased glomerular permeability. Kidney Int 33:517-523, 1988
32. LELONGT B, CARONE FA, KANWAR YS: Decreased de novo synthesis of proteoglycans in drug-induced renal cystic disease. Proc Natl Acad Sci USA 85:9047-9051, 1988
33. PARTHASARATHY N, SPIRO RG: Effect of diabetes on the glycosaminoglycan component of the human glomerular basement membrane. Diabetes 31:738-741, 1982
34. SHIMOMURA H, SPIRO RG: Studies on macromolecular components of human glomerular basement membrane and alterations in diabetes; decreased levels of heparan sulfate proteoglycan and laminin. Diabetes 36:374-381, 1987
35. ROHRBACH DH, WAGNER CH, STAR VL, MARTIN GR, BROWN KS, YOON J-W: Reduced synthesis of basement membrane heparan sulfate proteoglycan in streptozotocin-induced diabetic mice. J Biol Chem 258:11672-11677, 1982
36. KANWAR YS, ROSENZWEIG LJ, LINKER A, JAKUBOWSKI ML: Decreased de novo synthesis of glomerular proteoglycans in diabetes: Biochemical and autoradiographic evidence. Proc Natl Acad Sci USA 80:2272-2275, 1983
37. 35S]-labeled glomerular basement membrane. Diabetes 33:8-12, 1984
38. GROGGEL GC, HOVINGH P, BORDER WA, LINKER A: Changes in glomerular heparan sulfate in puromycin aminonucleoside nephrosis. Am J Pathol 128:521-527, 1987
39. LELONGT B, MAKINO H, KANWAR YS: Status of glomerular proteoglycans in aminonucleoside nephrosis. Kidney Int 31:1299-1310, 1987
40. TEMPLETON DM: Retention of glomerular basement membrane-proteoglycans accompanying loss of anionic site staining in experimental diabetes. Lab Invest 61:202-211, 1989
41. VAN DEN HEUVEL LPWJ, VAN DEN BORN J, JALANKO H, SCHRÖDER CH, VEERKAMP JH, ASSMANN KJM, BERDEN JHM, HOLMBERG C, RAPOLA J, MONNENS LAH: The glycosaminoglycan content of renal basement membranes in the congenital nephrotic syndrome of the Finnish type. Pediatr Nephrol 6:10-15, 1992
42. HIRSCH HZ, AINSWORTH SK, SPICER SS, KURTZ EH, BRISSIE RM: Ultrastructural assessment of colloidal iron of the distribution and localization of anionic sites in human glomerulonephritides. Am J Pathol 102:99-107, 1981
43. FURNESS PN, TURNER DR, COTTON RE: Basement membrane charge in human glomerular disease. J Pathol 150:267-278, 1986
44. GOODE NP, SHIRES M, APARICIO SR, DAVISON AM: Cationic colloidal gold - a novel marker for the demonstration of glomerular polyanion status in routine renal biopsies. Nephrol Dial Transplant 6:923-930, 1991
45. MYNDERSE LA, HASSELL JR, KLEINMAN HK, MARTIN GR, MARTINEZ-HERNANDEZ A: Loss of heparan sulfate proteoglycan from glomerular basement membrane of nephrotic rats. Lab Invest 48:292-302, 1983
46. KEMENY E, FILLIT HM, DAMLE S, MAHABIR R, KEFALIDES NA, GREGORY JD, ANTONOVYCH T, SABNIS S, ZABRISKIE JB: Monoclonal antibodies to heparan sulfate proteoglycan: Development and application to the study of normal tissue and pathologic human kidney biopsies. Connect Tissue Res 18:9-25, 1988
47. OOMURA A, NAKAMURA T, ARAKAWA M, OOSHIMA A, ISEMURA M: Alterations in the extracellular matrix components in human glomerular diseases. Virchows Arch A 415:151-159, 1989
48. CARONE FA, MAKINO H, KANWAR YS: Basement membrane antigens in renal polycystic disease. Am J Pathol 130:466-471, 1988
49. DIXEY J, MOSS J, WOODROW DF, SHORE I, MAINI RN: SLE nephritis: An ultrastructural immunogold study to evaluate the relationship between immune complexes and the basement membrane components type IV collagen, fibronectin and heparan sulphate proteoglycans. Clin Nephrol 34:95-102, 1990
50. MOSS J, WOODROW DF, SHORE I, GOWER P, PHILLIPS M, SPIRO RG: Ultrastructural immunogold studies of heparan sulphate proteoglycans in normal human glomeruli and glomerulonephritis. J Pathol 161:137-143, 1990
51. NERLICH A, SCHLEICHER E: Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions. Am J Pathol 139:889-899, 1991
52. VAN DEN BORN J, VAN DEN HEUVEL LPWJ, BARKER MAH, VEERKAMP JH, ASSMANN KJM, BERDEN JHM: Monoclonal antibodies against human glomerular and GBM heparan sulfate proteoglycan. Characterization and distribution studies in normal tissues and glomerulopathies. (abstract) Kidney Int 37:445, 1990
53. VAN DEN HEUVEL LPWJ, VAN DEN BORN J, VAN DE VELDEN TJAM, VEERKAMP JH, MONNENS LAH, SCHRÖDER CH, BERDEN JHM: Isolation and partial characterization of heparan sulfate proteoglycan from the human glomerular basement membrane. Biochem J 264:457-465, 1989
54. SCHMIEDEKE TMJ, STÖCKL FW, WEBER R, SUGISAKI Y, BATSFORD SR, VOGT A: Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis. J Exp Med 169:1879-1894, 1989
55. STÖCKL F, SCHMIEDEKE T, MULLER S, ATANASSOV C, WALDHERR R, RODRIGUEZ-ITURBE B, SUSIZAKI Y, NAKABAYASHI K, NAGASAWA T, BATSFORD S, ANDRASSY K, VOGT A: Glomerular histone and ubiquitin deposits in biopsies of SLE patients. (abstract) J Am Soc Nephrol 1:541, 1990
56. CAMUSSI G, TETTA C, MAZZUCCO G, MONGA G, ROFFINELLO C, ALBERTON M, DELLABONA P, MALAVASI F, VERCELLONE A: Platelet cationic proteins are present in glomeruli of lupus nephritis patients. Kidney Int 30:555-565, 1986
57. TETTA C, CAVALLO-PERIN P, ROGGERO S, MALAVASI F, ESTIVI P, TRIOLO G, CAMUSSI G, PAGANO G: Exercise-induced microalbuminuria in diabetes is associated with the urinary excretion of cationic proteins. Clin Nephrol 30:270-275, 1988
58. LEVIN M, GASCOINE P, TURNER MW, BARRATT TM: A highly cationic protein in plasma and urine of children with steroid-responsive nephrotic syndrome. Kidney Int 36:867-877, 1989
59. 2-halide system in immune complex nephritis. Kidney Int 32:342-349, 1987
60. CAMUSSI G, TETTA C, MERONI M, TORRI-TARELLI L, ROFFINELLO C, ALBERTON A, DEREGIBUS C, SESSA A: Localization of cationic proteins derived from platelets and polymorphonuclear neutrophils and focal loss of anionic sites in glomeruli of rabbits with experimentally-induced acute serum sickness. Lab Invest 55:56-62, 1986
61. JOHNSON RJ, COUSER WG, ALPERS CE, VISSERS M, SCHULZE M, KLEBANOFF SJ: The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo. J Exp Med 168:1169-1174, 1988
62. BARNES JL, LEVINE SP, VENKATACHALAM MA: Binding of platelet factor four (PF 4) to glomerular anion. Kidney Int 25:759-765, 1984
63. WU V-Y, COHEN MP: Platelet factor 4 binding to glomerular microvascular matrix. Biochim Biophys Acta 797:76-82, 1984
64. CARRIE BJ, SALYER WR, MYERS BD: Minimal change nephropathy: An electrochemical disorder of the glomerular membrane. Am J Med 70:262-268, 1981
65. TERMAAT R-M, BRINKMAN K, VAN GOMPEL F, VAN DEN HEUVEL LPWJ, VEERKAMP JH, SMEENK RJT, BERDEN JHM: Cross-reactivity of monoclonal anti-DNA antibodies with heparan sulfate is mediated via bound DNA/histone complexes. J Autoimmunity 3:531-545, 1990
66. BRINKMAN K, TERMAAT R-M, BERDEN JHM, SMEENK RJT: Anti-DNA antibodies and lupus nephritis: The complexity of crossreactivity. Immunol Today 11:232-234, 1990
67. KANWAR YS, ROSENZWEIG LJ, JAKUBOWSKI ML: Distribution of de novo synthesized sulfated glycosaminoglycans in the glomerular basement membrane and mesangial matrix. Lab Invest 49:216-225, 1983
68. STRIKER GE, KILLEN PD, FARIN FM: Human glomerular cells in vitro: Isolation and characterization. Transplant Proc 12:88-99, 1980
69. YAOITA E, OGURI K, OKAYAMA E, KAWASAKI K, KOBAYASHI S, KIHARA I, OKAYAMA M: Isolation and characterization of proteoglycans synthesized by cultured mesangial cells. J Biol Chem 265:522-531, 1990
70. KLEIN DJ, BROWN DM, KIM Y, OEGEMA TR: Proteoglycans synthesized by human glomerular mesangial cells in culture. J Biol Chem 265:9533-9543, 1990
71. DOI T, STRIKER LJ, KIMATA K, PETEN EP, YAMADA Y, STRIKER GE: Glomerulosclerosis in mice transgenic for growth hormone. Increased mesangial extracellular matrix is correlated with kidney mRNA levels. J Exp Med 173:1287-1290, 1991
72. NAKAMURA T, EBIHARA I, SHIRATO I, TOMINO Y, KOIDE H: Modulation of basement membrane component gene expression in glomeruli of aminonucleoside nephrosis. Lab Invest 64:640-647, 1991
73. FUNABIKI K, HORIKOSHI S, TOMINO Y, NAGAI Y, KOIDE H: Immunohistochemical analysis of extracellular components in the glomerular sclerosis of patients with glomerulonephritis. Clin Nephrol 34:239-246, 1990
74. OKUDA S, LANGUINO LR, RUOSLAHTI E, BORDER WA: Elevated expression of transforming growth factor-B and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix. J Clin Invest 86:453-462, 1990
75. ABRASS CK, PETERSON CV, RAUGI GJ: Phenotypic expression of collagen types in mesangial matrix of diabetic and nondiabetic rats. Diabetes 37:1695-1702, 1988
76. KISILEVSKY R: Heparan sulfate proteoglycans in amyloidogenesis: An epiphenomenon, a unique factor, or the tip of a more fundamental process? Lab Invest 63:589-591, 1990
77. SNOW AD, MAR H, NOCHLIN D, SEKIGUCHI RT, KIMATA K, KOIKE Y, WIGHT TN: Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome. Am J Pathol 137:1253-1270, 1990
78. SNOW AD, WIGHT TN, NOCHLIN D, KOIKE Y, KIMATA K, DEARMOND SJ, PRUSINER SB: Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeld-Jakob disease and scrapie. Lab Invest 63:601-611, 1990
79. SNOW AD, MAR H, NOCHLIN D, KIMATA K, KATO M, SUZUKI S, HASSELL J, WIGHT TN: The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am J Pathol 133:456-463, 1988
80. NIEWOLD TA, FLORES LANDEIRA JM, VAN DEN HEUVEL LPWJ, ULTEE A, TOOTEN PCJ, VEERKAMP JH: Characterization of proteoglycans and glycosaminoglycans in bovine renal AA-type amyloidosis. Virchows Arch B 60:321-328, 1991
81. NORLING B, WESTERMARK GT, WESTERMARK P: Immunohistochemical identification of heparan sulphate proteoglycan in secondary systemic amyloidosis. Clin Exp Immunol 73:333-337, 1988