NMR studies of a complex of RNAse from Penicillium brevicompactum with dinucleoside phosphonate and the implications for the mechanism of enzyme action

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular

Volumn 1202, Issue 1, 1993, Pages 143-148

  Yakovlev, Gennady I ^a   Moiseyev, Gennady P ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Dinucleoside phosphonate; Guanylic RNase Pb1; Guanylic RNase T1; NMR, 31P

Indexed keywords

DINUCLEOSIDE PHOSPHONATE; RIBONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; ENZYME MECHANISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PENICILLIUM BREVICOMPACTUM; PRIORITY JOURNAL;

ASPERGILLUS; BINDING SITES; COMPARATIVE STUDY; DINUCLEOSIDE PHOSPHATES; GLUTAMATES; GLUTAMIC ACID; HISTIDINE; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; PENICILLIUM; RIBONUCLEASES;

PENICILLIUM BREVICOMPACTUM;

EID: 0027305576     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4838(93)90075-3     Document Type: Article

References (27)

1. Two histidine residues are essential for ribonuclease T1 activity as is the case for ribonuclease A
2. Use of 5-deoxy-ribo-hexofuranose derivatives for the preparation of 5'-nucleotide phosphonates and homoribonucleosides
3. Nucleoside, XXXVII. Synthese und Eigenschaften von 2′-O- und 3′-O-(tert-Butyldi-methylsilyl)-5′-O-(4-methoxytrityl)- sowie 2′,3′-Bis-O-(tert-butyl-dimethylsilyl)ribonucleosiden — Ausgangssubstanzen für Oligoribonucleotid-Synthesen