2′-Substituted Chalcone Derivatives as Inhibitors of Interleukin-1 Biosynthesis

Journal of Medicinal Chemistry

Volumn 36, Issue 10, 1993, Pages 1434-1442

  Batt, Douglas G ^a   Goodman, Robin ^a   Jones, David G ^a   Kerr, Janet S ^a   Mantegna, Lisa R ^a   McAllister, Candice ^a   Newton, Robert C ^a   Nurnberg, Sherrill ^a   Welch, Patricia K ^a   Covington, Maryanne B ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHALCONE DERIVATIVE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SEPTIC SHOCK; STRUCTURE ACTIVITY RELATION;

ANIMAL; CELL SURVIVAL; CHALCONE; FEMALE; HUMAN; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MONOCYTES; SHOCK, SEPTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0027297939     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00062a016     Document Type: Article

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