Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure—Activity Studies. 2. The Amide Bond “B-Region”

Journal of Medicinal Chemistry

Volumn 36, Issue 16, 1993, Pages 2373-2380

  Walpole, Christopher S J ^a   Wrigglesworth, Roger ^a   Bevan, Stuart ^a   Campbell, Elizabeth A ^a   Dray, Andy ^a   James, Iain F ^a   Masdin, Kay J ^a   Perkins, Martin N ^a   Winter, Janet ^a  

^a Sandoz Institute for Medical Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CALCIUM 45; CAPSAICIN; CAPSAICIN DERIVATIVE; THIOUREA DERIVATIVE; N (4 HYDROXY 3 METHOXYBENZYL) N' OCTYLTHIOUREA; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; HYDROPHOBICITY; MOUSE; NEWBORN; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION; DRUG RECEPTOR BINDING; HYDROGEN BOND; MOLECULAR DYNAMICS;

ANALGESICS; ANIMAL; CALCIUM; CALCIUM CHANNEL AGONISTS; CAPSAICIN; GANGLIA, SPINAL; GUINEA PIGS; ILEUM; MICE; MUSCLE CONTRACTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0027296078     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00068a015     Document Type: Article

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