Recursive partitioning analysis of prognostic factors in three radiation therapy oncology group malignant glioma trials

Journal of the National Cancer Institute

Volumn 85, Issue 9, 1993, Pages 704-710

  Curran, Walter J ^a   Scott, Charles B ^b   Horton, John ^c   Nelson, James S ^d   Weinstein, Alan S ^e   Fischbach, A Jennifer ^f   Chang, Chu H ^g   Rotman, Marvin ^h   Asbell, Sucha O ⁱ   Krisch, Robert E ^j   Nelson, Diane F ^k  

^a FOX CHASE CANCER CENTER   (United States)

^b RADIATION THERAPY ONCOLOGY GROUP   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^e Moorestown   (United States)

^f LDS HOSPITAL   (United States)

^g Columbia Presbyterian Hospital ^*  (United States)

^h STATE UNIVERSITY OF NEW YORK   (United States)

ⁱ Albert Einstein Medical Centre   (United States)

^j VETERANS AFFAIRS MEDICAL CENTER   (United States)

^k Highland Hospital Rochester   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; DACARBAZINE; MISONIDAZOLE; SEMUSTINE;

ADULT; AGE; AGED; ARTICLE; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CLINICAL FEATURE; FEMALE; GLIOBLASTOMA; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; PERFORMANCE; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGNOSIS; REGRESSION ANALYSIS;

ADULT; AGE FACTORS; AGED; BRAIN NEOPLASMS; FEMALE; GLIOMA; HUMAN; MALE; MIDDLE AGE; PROGNOSIS; RETROSPECTIVE STUDIES; STATISTICS; SUPPORT, U.S. GOV'T, P.H.S.; SURVIVAL ANALYSIS;

EID: 0027294649     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/85.9.704     Document Type: Article

References (27)

1. Walker MD, Green SB, Byar DP, et al: Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N Engl J Med 303:1323-1329, 1980.
2. Chano CH, Horton J, Schoenfeld D, et al: Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A Joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology study. Cancer 52:997-1007, 1983.
3. Nelson DF, Diener-West M, Weinstein AS, et al: A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: Final report of an RTOG study. Int J Radiat Oncol Biol Phys12:1793-1800, 1986.
4. Deutsch M, Green SB, Strike TA, et al: Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma. Int J Radiat Oncol Biol Phys 16:1389-1396, 1989.
5. Shapiro WR, Green SB, Burger PC, et al: Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001. J Neurosurg 71:1-9, 1989.
6. Rozental JM, Robins HI, Finlay J, et al “Eight-drugs-in-one-day” chemotherapy administered before and after radiotherapy to adult patients with malignant gliomas. Cancer 63:2475-2481, 1989.
7. Nelson DF, Curran WJ Jr., Scott CB, et al Hyperfractionated radiation therapy and bis-chloroethyl nitrosourea in the treatment of malignant glioma: Possible advantage observed at 72.0 Gy in 1.2-Gy BID fractions: Report of the RTOG protocol 8302. Int J Radiat Oncol Biol Phys 25:193-207, 1993.
8. Curran WJJr., Scott CB, Nelson JS, et al A randomized trial of accelerated hyperfractionated radiation therapy and bis-chloroethyl nitrosourea for malignant glioma: A preliminary report of Radiation Therapy Oncology Group 83-02. Cancer 70:2909-2917, 1992.
9. Gutin PH, Prados MD, Phillips TL, et al: External irradiation followed by a interstitial high activity iodine-125 implant "boost” in the initial treatment of malignant gliomas: NCOG Study 6G-82-2. Int J Radiat Oncol Biol Phys 21:601-606, 1991.
10. Loeffler JS, Alexander E III, Shea WM, et al: Radiosurgery as part of the initial management of patients with malignant gliomas. J Clin Oncol 10:1379-1385, 1992.
11. Levtn VA, Wara WM, Gutin CB, et al: Initial analysis of NCOG 6G82-1: Bromodeoxyuridine (BUdR) during irradiation followed by CCNU, procarbazine, and vincristine (PCV) chemotherapy for malignant glioma. Proc ASCO 9:91, 1990.
12. Zelen M: The randomization and stratification of patients to clinical trials. J Chronic Dis 27:365-375, 1974.
13. Ciampi A, Thiffault J: Recursive partition and amalgamation (RECPAM) for censored survival data: Criteria for tree selection. Stat Soft News 14:78-81, 1988.
14. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958.
15. Gordon L, Olshen RA: Tree-structured survival analysis. Cancer Treat Rep 69:1065-1069, 1985.
16. Peto R, Pike MC, Armftage P, et al: Design and analysis of randomised clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 35:1-39, 1977.
17. Prentice RL, Marek P: A qualified discrepancy between censored data rank tests. Biometrics 35:861-867, 1979.
18. Hommel G: A stagewise rejective multiple test procedure based on a modified Bonferroni test. Biometrika 75:383-386, 1988.
19. Hommel G: A comparison of two modified Bonferroni procedures. Biometrika 76:624-625, 1989.
20. Cox DR: Regression models and life tables. J R Stat Soc Series B34:187-229, 1972.
21. Albain KS, Crowley JJ, LeBlanc M, et al: Determinants of improved outcome in small-cell lung cancer An analysis of the 2,580-patient Southwest Oncology Group data base. J Clin Oncol 8,1563-1574, 1990.
22. Leibel SA, Scott CB, Pajak TF: The management of malignant gliomas with radiation therapy: Therapeutic results and research strategies. Semin Radiat Oncol 1:32-49, 1991.
23. Greig NH, Ries LG, Yancik R, et al: Increasing annual incidence of primary malignant brain tumors in the elderly. J Natl Cancer Inst82:1621-1624, 1990.
24. Hernandez JC, Maruyama Y, Yaes R, et al: Accelerated fractionaUon radiotherapy for hospitalized glioblastoma multiforme patients with poor prognostic factors. J Neurooncol 9:41-45, 1990.
25. Tamura M, Nakamura M, Kunimine H, el al: Large dose fraction radiotherapy in the treatment of glioblastoma. J Neurooncol 7:113-119, 1989.
26. Shapiro WR: Recent results and current protocols of the Brain Tumor Cooperative Group. J Neurooncol 12:241, 1992.
27. Phillips T, Prados MD, Bodell WJ, et al: Rationale for and experience with clinical trials of halogenated pyrimidines in malignant gliomas: The UCSF/NCOG experience. In Radiation Research-A Twentieth Century Prospective (Dewey WC, Edington M, Fry RJM, et al, eds), vol 2. New York: Academic Press, 1992, pp 601-606.