Rational design of potent sialidase-based inhibitors of influenza virus replication

Nature

Volumn 363, Issue 6428, 1993, Pages 418-423

  Von Itzstein, Mark ^a   Wu, Wen Yang ^a   Kok, Gaik B ^a   Pegg, Michael S ^a   Dyason, Jeffrey C ^a   Jin, Betty ^a   Phan, Tho Van ^a   Smythe, Mark L ^a   White, Hume F ^a,d   Oliver, Stuart W ^a   Colman, Peter M ^b   Varghese, Joseph N ^b   Ryan, D Michael ^c   Woods, Jacqueline M ^c   Bethell, Richard C ^c   Hotham, Vanessa J ^c   Cameron, Janet M ^c   Penn, Charles R ^c  

^a MONASH UNIVERSITY   (Australia)

^b CSIRO MOLECULAR AND HEALTH TECHNOLOGIES   (Australia)

^c GLAXOSMITHKLINE   (United Kingdom)

^d CSIRO TEXTILE AND FIBRE TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; ENZYME INHIBITOR; SIALIDASE INHIBITOR;

ARTICLE; DRUG DESIGN; INFLUENZA; INFLUENZA VIRUS; PRIORITY JOURNAL; VIRUS REPLICATION;

ANIMAL; ANTIVIRAL AGENTS; CELL LINE; COMPUTER-AIDED DESIGN; DISEASE MODELS, ANIMAL; DRUG DESIGN; FEMALE; FERRETS; HUMAN; INFLUENZA; INFLUENZA A VIRUS, HUMAN; MICE; MODELS, MOLECULAR; NEURAMINIDASE; PLAQUE ASSAY; SHEEP; SIALIC ACIDS; SUPPORT, NON-U.S. GOV'T; VIRUS REPLICATION;

ANIMALIA; INFLUENZA VIRUS;

EID: 0027287506     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/363418a0     Document Type: Article

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